메뉴 건너뛰기




Volumn 20, Issue 12, 2002, Pages 508-515

Lactobacilli as live vaccine delivery vectors: Progress and prospects

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; CLONING; IMMUNOLOGY; VACCINES;

EID: 0036890247     PISSN: 01677799     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-7799(02)02075-9     Document Type: Review
Times cited : (209)

References (64)
  • 1
    • 0035989641 scopus 로고    scopus 로고
    • In situ delivery of passive immunity by lactobacilli producing single-chain antibodies
    • Kruger C., et al. In situ delivery of passive immunity by lactobacilli producing single-chain antibodies. Nat. Biotechnol. 20:2002;702-706.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 702-706
    • Kruger, C.1
  • 2
    • 0034771290 scopus 로고    scopus 로고
    • Recombinant Lactobacillus plantarum inhibits house dust mite-specific T-cell responses
    • Kruisselbrink A., et al. Recombinant Lactobacillus plantarum inhibits house dust mite-specific T-cell responses. Clin. Exp. Immunol. 126:2001;2-8.
    • (2001) Clin. Exp. Immunol. , vol.126 , pp. 2-8
    • Kruisselbrink, A.1
  • 3
    • 0025440041 scopus 로고
    • In defense of mucosal surfaces. Development of novel vaccines for IgA responses protective at the portals of entry of microbial pathogens
    • McGhee J.R., Mestecky J. In defense of mucosal surfaces. Development of novel vaccines for IgA responses protective at the portals of entry of microbial pathogens. Infect. Dis. Clin. North Am. 4:1990;315-341.
    • (1990) Infect. Dis. Clin. North Am. , vol.4 , pp. 315-341
    • McGhee, J.R.1    Mestecky, J.2
  • 4
    • 0035426510 scopus 로고    scopus 로고
    • Immunomodulators and delivery systems for vaccination by mucosal routes
    • Ryan E.J., et al. Immunomodulators and delivery systems for vaccination by mucosal routes. Trends Biotechnol. 19:2001;293-304.
    • (2001) Trends Biotechnol. , vol.19 , pp. 293-304
    • Ryan, E.J.1
  • 5
    • 0035825602 scopus 로고    scopus 로고
    • Use of live bacterial vaccine vectors for antigen delivery: Potential and limitations
    • Medina E., Guzman C.A. Use of live bacterial vaccine vectors for antigen delivery: Potential and limitations. Vaccine. 19:2001;1573-1580.
    • (2001) Vaccine , vol.19 , pp. 1573-1580
    • Medina, E.1    Guzman, C.A.2
  • 6
    • 0031081490 scopus 로고    scopus 로고
    • Oral delivery of foreign antigens by attenuated Salmonella: Consequences of prior exposure to the vector strain
    • Attridge S.R., et al. Oral delivery of foreign antigens by attenuated Salmonella: Consequences of prior exposure to the vector strain. Vaccine. 15:1997;155-162.
    • (1997) Vaccine , vol.15 , pp. 155-162
    • Attridge, S.R.1
  • 7
    • 0036151762 scopus 로고    scopus 로고
    • Production and targeting of the Brucella abortus antigen L7/L12 in Lactococcus lactis: A first step towards food-grade live vaccines against brucellosis
    • Ribeiro L.A., et al. Production and targeting of the Brucella abortus antigen L7/L12 in Lactococcus lactis: A first step towards food-grade live vaccines against brucellosis. Appl. Environ. Microbiol. 68:2002;910-916.
    • (2002) Appl. Environ. Microbiol. , vol.68 , pp. 910-916
    • Ribeiro, L.A.1
  • 8
    • 0035898938 scopus 로고    scopus 로고
    • Expression of Helicobacter pylori urease subunit B gene in Lactococcus lactis MG1363 and its use as a vaccine delivery system against H. pylori infection in mice
    • Lee M.H., et al. Expression of Helicobacter pylori urease subunit B gene in Lactococcus lactis MG1363 and its use as a vaccine delivery system against H. pylori infection in mice. Vaccine. 19:2001;3927-3935.
    • (2001) Vaccine , vol.19 , pp. 3927-3935
    • Lee, M.H.1
  • 9
    • 0033586435 scopus 로고    scopus 로고
    • Antigenicity and immunogenicity of the V3 domain of HIV type 1 glycoprotein 120 expressed on the surface of Streptococcus gordonii
    • Oggioni M.R., et al. Antigenicity and immunogenicity of the V3 domain of HIV type 1 glycoprotein 120 expressed on the surface of Streptococcus gordonii. AIDS Res. Hum. Retroviruses. 15:1999;451-459.
    • (1999) AIDS Res. Hum. Retroviruses , vol.15 , pp. 451-459
    • Oggioni, M.R.1
  • 10
    • 0034168257 scopus 로고    scopus 로고
    • Expression of measles virus antigens in Streptococcus gordonii
    • Maggi T., et al. Expression of measles virus antigens in Streptococcus gordonii. New Microbiol. 23:2000;119-128.
    • (2000) New Microbiol. , vol.23 , pp. 119-128
    • Maggi, T.1
  • 11
    • 0032820970 scopus 로고    scopus 로고
    • Expression of the protective antigen of Bacillus anthracis by Lactobacillus casei: Towards the development of an oral vaccine against anthrax
    • Zegers N.D., et al. Expression of the protective antigen of Bacillus anthracis by Lactobacillus casei: Towards the development of an oral vaccine against anthrax. J. Appl. Microbiol. 87:1999;309-314.
    • (1999) J. Appl. Microbiol. , vol.87 , pp. 309-314
    • Zegers, N.D.1
  • 12
    • 0035316823 scopus 로고    scopus 로고
    • Bovine rotavirus nonstructural protein 4 produced by Lactococcus lactis is antigenic and immunogenic
    • Enouf V., et al. Bovine rotavirus nonstructural protein 4 produced by Lactococcus lactis is antigenic and immunogenic. Appl. Environ. Microbiol. 67:2001;1423-1428.
    • (2001) Appl. Environ. Microbiol. , vol.67 , pp. 1423-1428
    • Enouf, V.1
  • 13
    • 0033858446 scopus 로고    scopus 로고
    • Engineering the microflora to vaccinate the mucosa: Serum immunoglobulin G responses and activated draining cervical lymph nodes following mucosal application of tetanus toxin fragment C-expressing lactobacilli
    • Shaw D.M., et al. Engineering the microflora to vaccinate the mucosa: Serum immunoglobulin G responses and activated draining cervical lymph nodes following mucosal application of tetanus toxin fragment C-expressing lactobacilli. Immunology. 100:2000;510-518.
    • (2000) Immunology , vol.100 , pp. 510-518
    • Shaw, D.M.1
  • 14
    • 0035118294 scopus 로고    scopus 로고
    • Mucosal immune responses and protection against tetanus toxin after intranasal immunization with recombinant Lactobacillus plantarum
    • Grangette C., et al. Mucosal immune responses and protection against tetanus toxin after intranasal immunization with recombinant Lactobacillus plantarum. Infect. Immun. 69:2001;1547-1553.
    • (2001) Infect. Immun. , vol.69 , pp. 1547-1553
    • Grangette, C.1
  • 15
    • 0035999456 scopus 로고    scopus 로고
    • Probiotics in clinical conditions
    • Marteau P.R. Probiotics in clinical conditions. Clin. Rev. Allergy. 22:2002;255-273.
    • (2002) Clin. Rev. Allergy. , vol.22 , pp. 255-273
    • Marteau, P.R.1
  • 16
    • 0032824799 scopus 로고    scopus 로고
    • Probiotics: From myth to reality. Demonstration of functionality in animal models of disease and in human clinical trials
    • Dunne C., et al. Probiotics: from myth to reality. Demonstration of functionality in animal models of disease and in human clinical trials. Antonie Van Leeuwenhoek. 76:1999;279-292.
    • (1999) Antonie Van Leeuwenhoek , vol.76 , pp. 279-292
    • Dunne, C.1
  • 17
    • 0035820307 scopus 로고    scopus 로고
    • Probiotics in primary prevention of atopic disease: A randomised placebo-controlled trial
    • Kalliomaki M., et al. Probiotics in primary prevention of atopic disease: A randomised placebo-controlled trial. Lancet. 357:2001;1076-1079.
    • (2001) Lancet , vol.357 , pp. 1076-1079
    • Kalliomaki, M.1
  • 18
    • 0033597103 scopus 로고    scopus 로고
    • Instruments for oral disease-intervention strategies: Recombinant Lactobacillus casei expressing tetanus toxin fragment C for vaccination or myelin proteins for oral tolerance induction in multiple sclerosis
    • Maassen C.B., et al. Instruments for oral disease-intervention strategies: Recombinant Lactobacillus casei expressing tetanus toxin fragment C for vaccination or myelin proteins for oral tolerance induction in multiple sclerosis. Vaccine. 17:1999;2117-2128.
    • (1999) Vaccine , vol.17 , pp. 2117-2128
    • Maassen, C.B.1
  • 19
    • 0034069779 scopus 로고    scopus 로고
    • Immunologic effects of yogurt
    • Meydani S.N., Ha W.K. Immunologic effects of yogurt. Am. J. Clin. Nutr. 71:2000;861-872.
    • (2000) Am. J. Clin. Nutr. , vol.71 , pp. 861-872
    • Meydani, S.N.1    Ha, W.K.2
  • 20
    • 0033769341 scopus 로고    scopus 로고
    • Importance of intestinal colonisation in the maturation of humoral immunity in early infancy: A prospective follow up study of healthy infants aged 0-6 months
    • Gronlund M.M., et al. Importance of intestinal colonisation in the maturation of humoral immunity in early infancy: A prospective follow up study of healthy infants aged 0-6 months. Arch. Dis. Child. Fetal Neonatal Ed. 83:2000;F186-F192.
    • (2000) Arch. Dis. Child. Fetal Neonatal Ed. , vol.83
    • Gronlund, M.M.1
  • 21
    • 0026724964 scopus 로고
    • Enhancement of the circulating antibody secreting cell response in human diarrhea by a human Lactobacillus strain
    • Kaila M., et al. Enhancement of the circulating antibody secreting cell response in human diarrhea by a human Lactobacillus strain. Pediatr. Res. 32:1992;141-144.
    • (1992) Pediatr. Res. , vol.32 , pp. 141-144
    • Kaila, M.1
  • 22
    • 0036100577 scopus 로고    scopus 로고
    • Activation of human NK cells by staphylococci and lactobacilli requires cell contact-dependent costimulation by autologous monocytes
    • Haller D., et al. Activation of human NK cells by staphylococci and lactobacilli requires cell contact-dependent costimulation by autologous monocytes. Clin. Diagn. Lab. Immunol. 9:2002;649-657.
    • (2002) Clin. Diagn. Lab. Immunol. , vol.9 , pp. 649-657
    • Haller, D.1
  • 23
    • 0036582429 scopus 로고    scopus 로고
    • Dietry intake of Lactobacillus rhamnosus HNOO1 enhances production of both Th1 and Th2 cytokines in antigen-primed mice
    • Cross M.L., et al. Dietry intake of Lactobacillus rhamnosus HNOO1 enhances production of both Th1 and Th2 cytokines in antigen-primed mice. Med. Microbiol. Immunol. 191:2002;49-53.
    • (2002) Med. Microbiol. Immunol. , vol.191 , pp. 49-53
    • Cross, M.L.1
  • 24
    • 0034701834 scopus 로고    scopus 로고
    • Strain-dependent induction of cytokine profiles in the gut by orally administered Lactobacillus strains
    • Maassen C.B., et al. Strain-dependent induction of cytokine profiles in the gut by orally administered Lactobacillus strains. Vaccine. 18:2000;2613-2623.
    • (2000) Vaccine , vol.18 , pp. 2613-2623
    • Maassen, C.B.1
  • 25
    • 0030040761 scopus 로고    scopus 로고
    • The potential of Lactobacillus as a carrier for oral immunization: Development and preliminary characterization of vector systems for targeted delivery of antigens
    • Pouwels P.H., et al. The potential of Lactobacillus as a carrier for oral immunization: development and preliminary characterization of vector systems for targeted delivery of antigens. J. Biotechnol. 44:1996;183-192.
    • (1996) J. Biotechnol. , vol.44 , pp. 183-192
    • Pouwels, P.H.1
  • 26
    • 0036136282 scopus 로고    scopus 로고
    • Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells
    • Christensen H.R., et al. Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells. J. Immunol. 168:2002;171-178.
    • (2002) J. Immunol. , vol.168 , pp. 171-178
    • Christensen, H.R.1
  • 27
    • 0032167625 scopus 로고    scopus 로고
    • Studying M cells and their role in infection
    • Jepson M.A., Clark M.A. Studying M cells and their role in infection. Trends Microbiol. 6:1998;359-365.
    • (1998) Trends Microbiol. , vol.6 , pp. 359-365
    • Jepson, M.A.1    Clark, M.A.2
  • 28
    • 0035321325 scopus 로고    scopus 로고
    • Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria
    • Rescigno M., et al. Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat. Immunol. 2:2001;361-367.
    • (2001) Nat. Immunol. , vol.2 , pp. 361-367
    • Rescigno, M.1
  • 29
    • 0030666222 scopus 로고    scopus 로고
    • Innate immunity: The virtues of a nonclonal system of recognition
    • Medzhitov R., Janeway C.A.J. Innate immunity: the virtues of a nonclonal system of recognition. Cell. 91:1997;295-298.
    • (1997) Cell , vol.91 , pp. 295-298
    • Medzhitov, R.1    Janeway, C.A.J.2
  • 31
    • 0032807417 scopus 로고    scopus 로고
    • The role of B7 costimulation in T-cell immunity
    • Harris N.L., Ronchese F. The role of B7 costimulation in T-cell immunity. Immunol. Cell. Biol. 77:1999;304-311.
    • (1999) Immunol. Cell. Biol. , vol.77 , pp. 304-311
    • Harris, N.L.1    Ronchese, F.2
  • 32
    • 0034284803 scopus 로고    scopus 로고
    • Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination
    • Neish A.S., et al. Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination. Science. 289:2000;1560-1563.
    • (2000) Science , vol.289 , pp. 1560-1563
    • Neish, A.S.1
  • 33
    • 0031815046 scopus 로고    scopus 로고
    • Mucosal delivery of murine interleukin-2 (IL-2) and IL-6 by recombinant strains of Lactococcus lactis coexpressing antigen and cytokine
    • Steidler L., et al. Mucosal delivery of murine interleukin-2 (IL-2) and IL-6 by recombinant strains of Lactococcus lactis coexpressing antigen and cytokine. Infect. Immun. 66:1998;3183-3189.
    • (1998) Infect. Immun. , vol.66 , pp. 3183-3189
    • Steidler, L.1
  • 34
    • 0030721749 scopus 로고    scopus 로고
    • Controlled gene expression systems for lactic acid bacteria: Transferable nisin-inducible expression cassettes for Lactococcus, Leuconostoc, and Lactobacillus spp
    • Kleerebezem M., et al. Controlled gene expression systems for lactic acid bacteria: Transferable nisin-inducible expression cassettes for Lactococcus, Leuconostoc, and Lactobacillus spp. Appl. Environ. Microbiol. 63:1997;4581-4584.
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 4581-4584
    • Kleerebezem, M.1
  • 35
    • 0033781867 scopus 로고    scopus 로고
    • Adaptation of the nisin-controlled expression system in Lactobacillus plantarum: A tool to study in vivo biological effects
    • Pavan S., et al. Adaptation of the nisin-controlled expression system in Lactobacillus plantarum: A tool to study in vivo biological effects. Appl. Environ. Microbiol. 66:2000;4427-4432.
    • (2000) Appl. Environ. Microbiol. , vol.66 , pp. 4427-4432
    • Pavan, S.1
  • 36
    • 0030931978 scopus 로고    scopus 로고
    • Regulation of expression of the Lactobacillus pentosus xylAB operon
    • Lokman B.C., et al. Regulation of expression of the Lactobacillus pentosus xylAB operon. J. Bacteriol. 179:1997;5391-5397.
    • (1997) J. Bacteriol. , vol.179 , pp. 5391-5397
    • Lokman, B.C.1
  • 37
    • 0037086567 scopus 로고    scopus 로고
    • Comparison of the immune responses induced by local immunizations with recombinant Lactobacillus plantarum producing tetanus toxin fragment C in different cellular locations
    • Reveneau N., et al. Comparison of the immune responses induced by local immunizations with recombinant Lactobacillus plantarum producing tetanus toxin fragment C in different cellular locations. Vaccine. 20:2002;1769-1777.
    • (2002) Vaccine , vol.20 , pp. 1769-1777
    • Reveneau, N.1
  • 38
    • 0034990590 scopus 로고    scopus 로고
    • Lactobacilli as vehicles for targeting antigens to mucosal tissues by surface exposition of foreign antigens
    • Pouwels P.H., et al. Lactobacilli as vehicles for targeting antigens to mucosal tissues by surface exposition of foreign antigens. Methods Enzymol. 336:2001;369-389.
    • (2001) Methods Enzymol. , vol.336 , pp. 369-389
    • Pouwels, P.H.1
  • 39
    • 0032743093 scopus 로고    scopus 로고
    • Efficiency of transcription from promoter sequence variants in Lactobacillus is both strain and context dependent
    • McCracken A., Timms P. Efficiency of transcription from promoter sequence variants in Lactobacillus is both strain and context dependent. J. Bacteriol. 181:1999;6569-6572.
    • (1999) J. Bacteriol. , vol.181 , pp. 6569-6572
    • McCracken, A.1    Timms, P.2
  • 40
    • 0028804911 scopus 로고
    • Effects of rare codon clusters on high-level expression of heterologous proteins in Escherichia coli
    • Kane J.F. Effects of rare codon clusters on high-level expression of heterologous proteins in Escherichia coli. Curr. Opin. Biotechnol. 6:1995;494-500.
    • (1995) Curr. Opin. Biotechnol. , vol.6 , pp. 494-500
    • Kane, J.F.1
  • 41
    • 0028272132 scopus 로고
    • Divergence in codon usage of Lactobacillus species
    • Pouwels P.H., Leunissen J.A. Divergence in codon usage of Lactobacillus species. Nucleic Acids Res. 22:1994;929-936.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 929-936
    • Pouwels, P.H.1    Leunissen, J.A.2
  • 42
    • 0027309534 scopus 로고
    • Lactococcus lactis: High-level expression of tetanus toxin fragment C and protection against lethal challenge
    • Wells J.M., et al. Lactococcus lactis: high-level expression of tetanus toxin fragment C and protection against lethal challenge. Mol. Microbiol. 8:1993;1155-1162.
    • (1993) Mol. Microbiol. , vol.8 , pp. 1155-1162
    • Wells, J.M.1
  • 43
    • 0023272674 scopus 로고
    • Immunization of mice against tetanus with fragments of tetanus toxin synthesized in Escherichia coli
    • Fairweather N.F., et al. Immunization of mice against tetanus with fragments of tetanus toxin synthesized in Escherichia coli. Infect. Immun. 55:1987;2541-2545.
    • (1987) Infect. Immun. , vol.55 , pp. 2541-2545
    • Fairweather, N.F.1
  • 44
    • 0030959610 scopus 로고    scopus 로고
    • A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigens
    • Galen J.E., et al. A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigens. Vaccine. 15:1997;700-708.
    • (1997) Vaccine , vol.15 , pp. 700-708
    • Galen, J.E.1
  • 45
    • 0035140008 scopus 로고    scopus 로고
    • Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin
    • Miyaji E.N., et al. Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin. Infect. Immun. 69:2001;869-874.
    • (2001) Infect. Immun. , vol.69 , pp. 869-874
    • Miyaji, E.N.1
  • 46
    • 0037157269 scopus 로고    scopus 로고
    • Use of a rationally attenuated Bordetella bronchiseptica as a live mucosal vaccine and vector for heterologous antigens
    • Stevenson A., Roberts M. Use of a rationally attenuated Bordetella bronchiseptica as a live mucosal vaccine and vector for heterologous antigens. Vaccine. 20:2002;2325-2335.
    • (2002) Vaccine , vol.20 , pp. 2325-2335
    • Stevenson, A.1    Roberts, M.2
  • 47
    • 0035852323 scopus 로고    scopus 로고
    • Tetanus toxin fragment C-specific priming by intranasal infection with recombinant Bordetella pertussis
    • Reveneau N., et al. Tetanus toxin fragment C-specific priming by intranasal infection with recombinant Bordetella pertussis. Vaccine. 20:2001;926-933.
    • (2001) Vaccine , vol.20 , pp. 926-933
    • Reveneau, N.1
  • 48
    • 0035961456 scopus 로고    scopus 로고
    • Immunization with recombinant Streptococcus gordonii expressing tetanus toxin fragment C confers protection from lethal challenge in mice
    • Medaglini D., et al. Immunization with recombinant Streptococcus gordonii expressing tetanus toxin fragment C confers protection from lethal challenge in mice. Vaccine. 19:2001;1931-1939.
    • (2001) Vaccine , vol.19 , pp. 1931-1939
    • Medaglini, D.1
  • 49
    • 0035685619 scopus 로고    scopus 로고
    • Surface display of recombinant proteins on Bacillus subtilis spores
    • Isticato R., et al. Surface display of recombinant proteins on Bacillus subtilis spores. J. Bacteriol. 183:2001;6294-6301.
    • (2001) J. Bacteriol. , vol.183 , pp. 6294-6301
    • Isticato, R.1
  • 50
    • 0030822890 scopus 로고    scopus 로고
    • Oral vaccination of mice against tetanus with recombinant Lactococcus lactis
    • Robinson K., et al. Oral vaccination of mice against tetanus with recombinant Lactococcus lactis. Nat. Biotechnol. 15:1997;653-657.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 653-657
    • Robinson, K.1
  • 51
    • 0024540908 scopus 로고
    • Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets
    • Heinzel F.P., et al. Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. J. Exp. Med. 169:1989;59-72.
    • (1989) J. Exp. Med. , vol.169 , pp. 59-72
    • Heinzel, F.P.1
  • 52
    • 0027155188 scopus 로고
    • TH1 and TH2 T-cell subsets are differentially activated by macrophages and B cells in murine leishmaniasis
    • Rossi-Bergmann B., et al. TH1 and TH2 T-cell subsets are differentially activated by macrophages and B cells in murine leishmaniasis. Infect. Immun. 61:1993;2266-2269.
    • (1993) Infect. Immun. , vol.61 , pp. 2266-2269
    • Rossi-Bergmann, B.1
  • 53
    • 0037178302 scopus 로고    scopus 로고
    • Recombinant Lactobacillus johnsonii as a mucosal vaccine delivery vehicle
    • Scheppler L., et al. Recombinant Lactobacillus johnsonii as a mucosal vaccine delivery vehicle. Vaccine. 20:2002;2913-2920.
    • (2002) Vaccine , vol.20 , pp. 2913-2920
    • Scheppler, L.1
  • 54
    • 0034826521 scopus 로고    scopus 로고
    • Recent developments in adjuvants for vaccines against infectious diseases
    • O'Hagan D.T., et al. Recent developments in adjuvants for vaccines against infectious diseases. Biomol. Eng. 18:2001;69-85.
    • (2001) Biomol. Eng. , vol.18 , pp. 69-85
    • O'Hagan, D.T.1
  • 55
    • 0032809376 scopus 로고    scopus 로고
    • A surface-displayed cholera toxin B peptide improves antibody responses using food-grade staphylococci for mucosal subunit vaccine delivery
    • Cano F., et al. A surface-displayed cholera toxin B peptide improves antibody responses using food-grade staphylococci for mucosal subunit vaccine delivery. FEMS Immunol. Med. Microbiol. 25:1999;289-298.
    • (1999) FEMS Immunol. Med. Microbiol. , vol.25 , pp. 289-298
    • Cano, F.1
  • 56
    • 0033568009 scopus 로고    scopus 로고
    • Human dendritic cells very efficiently present a heterologous antigen expressed on the surface of recombinant gram-positive bacteria to CD4+ T lymphocytes
    • Corinti S., et al. Human dendritic cells very efficiently present a heterologous antigen expressed on the surface of recombinant gram-positive bacteria to CD4+ T lymphocytes. J. Immunol. 163:1999;3029-3036.
    • (1999) J. Immunol. , vol.163 , pp. 3029-3036
    • Corinti, S.1
  • 57
    • 0034018609 scopus 로고    scopus 로고
    • Human dendritic cells are superior to B cells at presenting a major histocompatibility complex class II-restricted heterologous antigen expressed on recombinant Streptococcus gordonii
    • Corinti S., et al. Human dendritic cells are superior to B cells at presenting a major histocompatibility complex class II-restricted heterologous antigen expressed on recombinant Streptococcus gordonii. Infect. Immun. 68:2000;1879-1883.
    • (2000) Infect. Immun. , vol.68 , pp. 1879-1883
    • Corinti, S.1
  • 58
    • 0034714188 scopus 로고    scopus 로고
    • Treatment of murine colitis by Lactococcus lactis secreting interleukin-10
    • Steidler L., et al. Treatment of murine colitis by Lactococcus lactis secreting interleukin-10. Science. 289:2000;1352-1355.
    • (2000) Science , vol.289 , pp. 1352-1355
    • Steidler, L.1
  • 59
    • 0033142704 scopus 로고    scopus 로고
    • Study of the possible mechanisms involved in the mucosal immune system activation by lactic acid bacteria
    • Perdigon G., et al. Study of the possible mechanisms involved in the mucosal immune system activation by lactic acid bacteria. J. Dairy. Sci. 82:1999;1108-1114.
    • (1999) J. Dairy. Sci. , vol.82 , pp. 1108-1114
    • Perdigon, G.1
  • 60
    • 0033987529 scopus 로고    scopus 로고
    • Use of green fluorescent protein to tag lactic acid bacterium strains under development as live vaccine vectors
    • Geoffroy M.C., et al. Use of green fluorescent protein to tag lactic acid bacterium strains under development as live vaccine vectors. Appl. Environ. Microbiol. 66:2000;383-391.
    • (2000) Appl. Environ. Microbiol. , vol.66 , pp. 383-391
    • Geoffroy, M.C.1
  • 61
    • 0032400869 scopus 로고    scopus 로고
    • Mucosal immunity of the gastrointestinal tract and oral tolerance
    • Simecka J.W. Mucosal immunity of the gastrointestinal tract and oral tolerance. Adv. Drug Deliv. Rev. 34:1998;235-259.
    • (1998) Adv. Drug Deliv. Rev. , vol.34 , pp. 235-259
    • Simecka, J.W.1
  • 62
    • 0025080271 scopus 로고
    • Oral immunization with recombinant Streptococcus lactis carrying the Streptococcus mutans surface protein antigen gene
    • Iwaki M., et al. Oral immunization with recombinant Streptococcus lactis carrying the Streptococcus mutans surface protein antigen gene. Infect. Immun. 58:1990;2929-2934.
    • (1990) Infect. Immun. , vol.58 , pp. 2929-2934
    • Iwaki, M.1
  • 63
    • 0034971985 scopus 로고    scopus 로고
    • Design of a protein-targeting system for lactic acid bacteria
    • Dieye Y., et al. Design of a protein-targeting system for lactic acid bacteria. J. Bacteriol. 183:2001;4157-4166.
    • (2001) J. Bacteriol. , vol.183 , pp. 4157-4166
    • Dieye, Y.1
  • 64
    • 0035847002 scopus 로고    scopus 로고
    • The S-layer protein of Lactobacillus acidophilus ATCC 4356: Identification and characterisation of domains responsible for S-protein assembly and cell wall binding
    • Smit E., et al. The S-layer protein of Lactobacillus acidophilus ATCC 4356: identification and characterisation of domains responsible for S-protein assembly and cell wall binding. J. Mol. Biol. 305:2001;245-257.
    • (2001) J. Mol. Biol. , vol.305 , pp. 245-257
    • Smit, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.