Importance of intestinal colonisation in the maturation of humoral immunity in early infancy: A prospective follow up study of healthy infants aged 0-6 months

Archives of Disease in Childhood: Fetal and Neonatal Edition

Volumn 83, Issue 3, 2000, Pages

  Gronlund, M M ^a   Arvilommi, H ^b   Kero, P ^a   Lehtonen, O P ^a   Isolauri, E ^a  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

Delivery method; ELISPOT; Humoral immunity; Immune system; Immunoglobulin secreting cell; Intestinal colonisation

Indexed keywords

FOOD ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ALLERGIC DISEASE; ARTICLE; ARTIFICIAL MILK; BACTEROIDES FRAGILIS; BIFIDOBACTERIUM; BOTTLE FEEDING; BREAST FEEDING; BREAST MILK; CLOSTRIDIUM PERFRINGENS; CONTROLLED STUDY; FECES CULTURE; FECES MICROFLORA; FOLLOW UP; HUMAN; HUMORAL IMMUNITY; IMMUNOGLOBULIN PRODUCTION; IMMUNOMODULATION; INFANT; INTESTINE FLORA; LACTOBACILLUS; MONONUCLEAR CELL; NEWBORN; NORMAL HUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY;

EID: 0033769341     PISSN: 13592998     EISSN: 14682052     Source Type: Journal    
DOI: 10.1136/fn.83.3.f186     Document Type: Article

References (49)

1. Immunological aspects of host/microbiota interactions at the intestinal epithelium
2. The common mucosal immune system and current strategies for induction of immune responses in external secretions
3. Development of mucosal immune function in man: Potential for GI disease states
4. Immunoglobulin-containing cells in the intestinal mucosa and immunoglobulins in the intestinal juice in children
5. Ontogeny of secretory immunity: Levels of secretory IgA and natural antibodies in saliva
6. Lymphocyte subsets in jejunal and ileal Peyer's patches of normal and gnotobiotic minipigs
7. Immunohistochemical observations on lymphoid tissues from conventional and germ-free mice
8. The influence of exogenous antigenic stimulation on the specificity repertoire of background immunoglobulin-secreting cells of different isotypes
9. The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction
10. Appearance of secretory IgM and IgA antibodies to Escherichia coli in saliva during early infancy and childhood
11. Secretory IgA antibody response against Escherichia coli antigens in infants in relation to exposure
12. The antibody response in breast-fed and non-breast-fed infants after artificial colonization of the intestine with Escherichia coli O83
13. Development of anaerobic fecal flora in healthy newborn infants
14. Development of the faecal anaerobic microflora after caesarean section and treatment with antibiotics in newborn infants
15. Trends in the frequency of cesarean delivery. A 21-year experience, 1970-1990
16. At last, maternity statistics for England
17. Give us this day our daily germs
18. Colic for developmentalists
19. Faecal microflora in healthy infants born by different methods of delivery: Permanent changes in intestinal flora after caesarean delivery
20. A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells
21. A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells
22. Local immune response measured in blood lymphocytes reflects the clinical reactivity of children with cow's milk allergy
23. Immune response to prolonged intestinal exposure to antigen
24. Efficacy and safety of hydrolyzed cow milk and amino acid-derived formulas in infants with cow milk allergy
25. Infant feeding causes all cases of asthma, eczema, and hay fever. Or does it?
26. Age-related antibody response to food antigens
27. Immunoprophylaxis of atopy: Light at the end of the tunnel?
28. Intestinal flora in health and disease
29. Influence of two infant formulas and human milk on the development of the faecal flora in newborn infants
30. Development and differences of intestinal flora in the neonatal period in breast-fed and bottle-fed infants
31. Ecological control of the gastrointestinal tract. The role of probiotic flora
32. A serogrouping scheme for the study of the epidemiology of Bacteroides fragilis
33. Increase in the population of duodenal immunoglobulin A plasmocytes in axenic mice associated with different living or dead bacterial strains of intestinal origin
34. Digestive tract microflora liberates low molecular weight peptides with immunotriggering activity
35. Expression of a dietary protein in E. coli renders it strongly antigenic to gut lymphoid tissue
36. Early appearance of 'natural' mucosal IgA responses and germinal centers in suckling mice developing in the absence of maternal antibodies
37. Circulating immunoglobulin-secreting cells are heterogeneous in their expression of maturation markers and homing receptors
38. Identification of an intestinal immune response using peripheral blood lymphocytes
39. Immune response to acute diarrhea seen as circulating antibody-secreting cells
40. Production of predominantly polymeric IgA by human peripheral blood lymphocytes stimulated in vitro with mitogens
41. Contribution of immunoglobulin-secreting cells in the murine small intestine to the total 'background' immunoglobulin production
42. Background (spontaneous) immunoglobulin production in the murine small intestine as a function of age
43. Bacterial colonization of the large intestine in newborns delivered by cesarean section
44. Measles and atopy in Guinea-Bissau
45. Cross sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis A virus
46. The inverse association between tuberculin responses and atopic disorder
47. Asthma: An epidemic in the absence of infection?
48. T-helper polarization in atopic disease: How early does it occur?
49. Molecular and cellular aspects of the secretory immunoglobulin system