Antigenicity and immunogenicity of the V3 domain of HIV type 1 glycoprotein 120 expressed on the surface of Streptococcus gordonii

AIDS Research and Human Retroviruses

Volumn 15, Issue 5, 1999, Pages 451-459

  Oggioni, Marco R ^a   Medaglini, Donata ^a   Romano, Laura ^a   Peruzzi, Francesca ^a   Maggi, Tiziana ^a   Lozzi, Luisa ^a   Bracci, Luisa ^a   Zazzi, Maurizio ^a   Manca, Fabrizio ^b   Valensin, Pier E ^a   Pozzi, Gianni ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 120; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; VIRUS VECTOR;

ANTIBODY SPECIFICITY; ANTIGEN EXPRESSION; ANTIGENICITY; ARTICLE; CHEMICAL REACTION; GENE EXPRESSION; GRAM POSITIVE BACTERIUM; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOGENICITY; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; STREPTOCOCCUS GORDONII;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BLOTTING, WESTERN; CARRIER PROTEINS; DNA, VIRAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC VECTORS; HIV ANTIBODIES; HIV ANTIGENS; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HIV-1; HUMANS; IMMUNIZATION; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; STREPTOCOCCUS;

EID: 0033586435     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/088922299311204     Document Type: Article

References (31)

1. Lehner T, Wang J, Crange M, Mitchell E, Tao L, Hall G, Dennis N, Cook, Brookes R, Klavinskis LS, Jones I, Doyle L, and Ward R: Mucosal immunity elicited by target iliac lymphnode immunization with a subunit SIV envelope and core vaccine in macaques. Nature Med 1995;2:767-772.
2. Lehner T and Miller CJ: Rectal and genital immunization with SIV/HIV. In: Mucosal Vaccines (Kiyono H, Ogra PL, and McGhee JR, eds.), Vol. 27. Academic Press, San Diego, CA, 1996, pp. 357-371.
3. McGhee JR, Mestecky J, Dertzbaugh MT, Eldridge JH, Hirasawa M, and Kiyono H: The mucosal immune system: From fundamental concepts to vaccine development. Vaccine 1992;10:75-88.
4. Oggioni MR and Pozzi G: A host-vector system for heterologous gene expression in Streptococcus gordonii. Gene 1996;169:85-90.
5. Pozzi G, Oggioni MR, and Medaglini D: Recombinant Streptococcus gordonii as live vehicle for vaccine antigens. In: Gram-Positive Bacteria: Vaccine Vehicles for Mucosal Immunization (Pozzi G and Wells JM, eds.), Vol. 3. Springer-Verlag (Berlin) and Landes Bioscience (Georgetown, TX), 1997, pp. 35-60.
6. Rush CM, Mercenier A, and Pozzi G: Expression of vaccine antigens in Lactobacillus. In: Gram-Positive Bacteria: Vaccine Vehicles for Mucosal Immunization (Pozzi G and Wells JM, eds.), Vol. 6. Springer-Verlag (Berlin) and Landes Bioscience (Georgetown, TX), 1997, pp. 107-144.
7. Oggioni MR, Manganelli R, Contorni M, Tommasino M, and Pozzi G: Immunization of mice by oral colonization with live recombinant commensal streptococci. Vaccine 1995;13:775-779.
8. Medaglini D, Pozzi G, King TP, and Fischetti VA: Mucosal and systemic immune responses to a recombinant protein expressed on the surface of the oral commensal bacterium Streptococcus gordonii after oral colonization. Proc Natl Acad Sci USA 1995;92; 6868-6872.
9. Medaglini D, Rush CM, Sestini P, and Pozzi G: Commensal bacteria as vehicles for mucosal vaccines against sexually transmitted diseases: Vaginal colonisation with recombinant streptococci includes local and systemic antibodies in mice. Vaccine 1997;15: 1330-1337.
10. Medaglini D, Oggioni MR, and Pozzi G: Vaginal immunization with recombinant gram positive bacteria. Am J Reproduct Immunol 1998;39:199-208.
11. Di Fabio S, Medaglini D, Rush CM, Corrias G, Panzini GL, Pace M, Verani P, Pozzi G, and Titti F: Vaginal immunization of cynomolgus monkeys with Streptococcus gordonii expressing HIV-1 and HPV 16 antigens. Vaccine 1998;16:485-492.
12. Rescigno M, Citterio S, Thery C, Rittig M, Medaglini D, Pozzi G, Amigorena S, and Ricciardi-Castagnoli P: Bacterial-induced neobiosynthesis, stabilization and surface expression of functional class II molecules in mouse dendritic cells. Proc Natl Acad Sci USA 1998;95:5229-5234.
13. Pozzi G, Oggioni MR, Manganelli R, Medaglini D, Fischetti VA, Fenoglio D, Valle MT, Kunkl A, and Manca F: Human T-helper cell recognition of an immunodominant epitope of HIV-1 gp120 expressed on the surface of Streptococcus gordonii. Vaccine 1994;12:1071-1077.
14. 13a. Myers G, Hahn BH, Mellors JW, et al.: Human Retroviruses and AIDS 1995: A Compilation and Analysis of Nucleic Acid and Amino Acid Sequences. Theoretical Biology and Biophysics Group T-10, Los Alamos National Laboratory, Los Alamos, New Mexico, 1995.
15. Zazzi M, Romano L, Brasini A, and Valensin PE: Nested polymerase chain reaction for detection of human immunodeficiency virus type 1 DNA in clinical specimens. J Med Virol 1992;38:172-174.
16. Zazzi M, Romano L, Peruzzi F, Toneatto S, De Milito A, Botta G, and Valensin PE: Optimal conditions for detection of human immunodeficiency virus type 1 DNA by polymerase chain reaction with nested primers. Mol Cell Probes 1993;7:101-107.
17. Oggioni MR, Medaglini D, Contorni M, Cavalieri F, and Pozzi G: Expression of fusion proteins in the naturally transformable Streptococcus gordonii (Streptococcus sanguis) Challis. In: DNA Transfer and Gene Expression in Microorganisms (Balla E, Berencsi G, and Szentirmai A, eds.), Intercept, Andover, 1993, pp. 235-240.
18. Pozzi G, Contorni M, Oggioni MR, Manganelli R, Tommasino M, Cavalieri F, and Fischetti VA: Delivery and expression of a heterologous antigen on the surface of streptococci. Infect Immun 1992;60:1902-1907.
19. Pozzi G, Oggioni MR, Manganelli R, and Fischetti VA: Expression of M6 protein gene of Streptococcus pyogenes in Streptococcus gordonii after chromosomal integration and transcriptional fusion. Res Microbiol 1992;143:449-459.
20. Gorny MK, Xu J-Y, Gianakakos V, Karwowska S, Williams C, Sheppard HW, Hanson CV, and Zolla-Pazner S: Production of site-selected neutralizing human monoclonal antibodies against the third variable domain of the human immunodeficiency virus type 1 envelope glycoprotein. Proc Natl Acad Sci USA 1991;88: 3238-3242.
21. Fields GB and Noble RL: Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids. Int J Pept Protein Res 1990;35:161-214.
22. Rowland-Jones S, Tan R, and McMichael A: The role of cellular immunity in protection against HIV infection. Adv Immunol 1997;65:448-455.
23. Burton DN and Moore JP: Why do we not have an HIV vaccine and how can we make one? Nature Med 1998;4:495-498.
24. Aldovini A and Young R: Humoral and cell-mediated immune responses to live recombinant BCG-HIV vaccines. Nature (London) 1991;351:479-482.
25. Charbit A, Molla A, Ronco J, Clement JM, Favier V, Bahraoui EM, Montagnier L, Leguern A, and Hofnung M: Immunogenicity and antigenicity of conserved peptides from the envelope of HIV-1 expressed at the surface of recombinant bacteria. AIDS 1990;4:545-551.
26. Evans DJ, McKeating J, Meredith JM, Burke KL, Katrak K, John A, Ferguson M, Minor PD, Weiss RA, and Almond JW: An engineered poliovirus chimaera elicits broadly reactive HIV-1 neutralizing antibodies. Nature (London) 1989;339:385-388.
27. Frankel FR, Hedge S, Lieberman J, and Paterson Y: Induction of cell-mediated immune responses to human immunodeficiency virus type 1 Gag protein by using Listeria monocytogenes as a live vaccine vector. J Immunol 1995;155:4775-4782.
28. Jin Y, Giri C, Klutch MJ, Shepp D, and Wright SE: Improved immunogenicity of recombinant vaccinia virus-anchored gp120 lacking gp41. Vaccine 1993;11:1280-1282.
29. Wu S, Pascual DW, Lewis GK, and Hone DM: Induction of mucosal and systemic responses against human immunodeficiency virus type 1 glycoprotein 120 in mice after oral immunization with a single dose of a Salmonella-HIV vector. AIDS Res Hum Retroviruses 1997;13:1187-1194.
30. Dunstan SJ, Simmons CP, and Strugnell RA: Comparison of the abilities of different attenuated Salmonella typhimurium to elicit humoral immune responses against a heterologous antigen. Infect Immun 1998;66:732-740.
31. Guzman CA, Saverino D, Medina E, Fenoglio D, Gerstel B, Merlo A, Li Pira G, Buffa F, Chakraborty T, and Manca F: Attenuated Listeria monocytogenes carrier strains can deliver an HIV-1 gp120 T helper epitope to MHC class II-restricted CD4+ cells. Eur J Immunol 1998;28:1807-1814.