Making sense of the diverse ligand recognition by NKG2D

Journal of Immunology

Volumn 169, Issue 11, 2002, Pages 6279-6285

  Radaev, Sergei ^a   Kattah, Michael ^a   Zou, Zhongcheng ^a   Colonna, Marco ^b   Sun, Peter D ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NKG2D LIGAND; PROTEIN; RETINOIC ACID; UL16 BINDING PROTEIN; ULBP3 PROTEIN; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; IMMUNOGLOBULIN RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR; NATURAL KILLER CELL ACTIVATING RECEPTORS; RECOMBINANT PROTEIN;

ALGORITHM; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENERGY; GENE INDUCTION; GENE MUTATION; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; IN VITRO STUDY; METABOLISM; NUCLEOTIDE SEQUENCE; POINT MUTATION; PROTEIN CONFORMATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; CONSERVED SEQUENCE; DNA, COMPLEMENTARY; HYDROGEN BONDING; HYDROPHOBICITY; LIGANDS; MICE; MODELS, MOLECULAR; POINT MUTATION; PROTEIN CONFORMATION; RECEPTORS, IMMUNOLOGIC; RECOMBINANT PROTEINS;

EID: 0036883972     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.11.6279     Document Type: Article

References (40)

1. Cerwenka, A., and L. L. Lanier. 2001. Ligands for natural killer cell receptors: redundancy or specificity. Immunol. Rev. 181:158.
2. Ravetch, J. V., and L. L. Lanier. 2000. Immune inhibitory receptors. Science 290:84.
3. Long, E. O. 1999. Regulation of immune responses through inhibitory receptors. Annu. Rev. Immunol. 17:875.
4. Smith, H. R., A. H. Idris, and W. M. Yokoyama. 2001. Murine natural killer cell activation receptors. Immunol. Rev. 181:115.
5. Diefenbach, A., and D. H. Raulet. 2001. Strategies for target cell recognition by natural killer cells. Immunol. Rev. 181:170.
6. Boyington, J. C., S. A. Motyka, P. Schuck, A. G. Brooks, and P. D. Sun. 2000. Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand. Nature 405:537.
7. Fan, Q. R., E. O. Long, and D. C. Wiley. 2001. Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex. Nat. Immunol. 2:452.
8. Tormo, J., K. Natarajan, D. H. Margulies, and R. A. Mariuzza. 1999. Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand. Nature 402:623.
9. Bauer, S., V. Groh, J. Wu, A. Steinle, J. H. Phillips, L. L. Lanier, and T. Spies. 1999. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285:727.
10. Cosman, D., J. Mullberg, C. L. Sutherland, W. Chin, R. Armitage, W. Fanslow, M. Kubin. and N. J. Chalupny. 2001. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity 14:123.
11. Cerwenka, A., A. B. Bakker, T. McClanahan. J. Wagner, J. Wu, J. H. Phillips, and L. L. Lanier. 2000. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity 12:721.
12. Diefenbach, A., A. M. Jamieson, S. D. Liu, N. Shastri, and D. H. Raulet. 2000. Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nat. Immunol. 1:119.
13. Winter, C. C., and E. O. Long. 1997. A single amino acid in the p58 killer cell inhibitory receptor controls the ability of natural killer cells to discriminate between the two groups of HLA-C allotypes. J. Immunol. 158:4026.
14. Colonna, M., G. Borsellino, M. Falco, G. B. Ferrara, and J. L. Strominger. 1993. HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells. Proc. Natl. Acad. Sci. USA 90:12000.
15. Wolan, D. W., L. Teyton, M. G. Rudolph, B. Villmow, S. Bauer, D. H. Busch, and I. A. Wilson. 2001. Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A. Nat. Immunol. 2:248.
16. Li, P., G. McDermott, and R. K. Strong. 2002. Crystal structures of RAE-1β and its complex with the activating immunoreceptor NKG2D. Immunity 16:77.
17. Li, P., D. L. Morris, B. E. Willcox, A. Steinle, T. Spies, and R. K. Strong. 2001. Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA. Nat. Immunol. 2:443.
18. Radaev, S., B. Rostro, A. G. Brooks, M. Colonna, and P. D. Sun. 2001. Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3. Immunity 15:1.
19. Kleywegt, G. J., and T. A. Jones. 1995. Where freedom is given, liberties are taken. Structure. 3:535.
20. Snyder, G. A., A. G. Brooks, and P. D. Sun. 1999. Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2. Proc. Natl. Acad. Sci. USA 96:3864.
21. Lawrence, M. C., and P. M. Colman. 1993. Shape complementarity at protein/protein interfaces. J. Mol. Biol. 234:946.
22. Ysern, X., H. Li, and R. A. Mariuzza. 1998. Imperfect interfaces. Nat. Struct. Biol. 5:412.
23. Wang, J. H., A. Smolyar, K. Tan, J. H. Liu, M. Kim, Z. Y. Sun, G. Wagner, and E. L. Reinherz. 1999. Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors. Cell 97:791.
24. Wagtmann, N., S. Rajagopalan, C. C. Winter, M. Peruzzi, and E. O. Long. 1995. Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer. Immunity 3:801.
25. Gumperz, J. E., L. D. Barber, N. M. Valiante, L. Percival, J. H. Phillips, L. L. Lanier. and P. Parham. 1997. Conserved and variable residues within the Bw4 motif of HLA-B make separable contributions to recognition by the NKB1 killer cell-inhibitory receptor. J. Immunol. 158:5237.
26. + IL-2-activated natural killer cells. Nature 358:66.
27. Yokoyama, W. M. 1998. Natural killer cell receptors. Curr. Opin. Immunol. 10:298.
28. Braud, V. M., D. S. Allan, C. A. O'Callaghan, K. Soderstrom, A. D'Andrea, G. S. Ogg, S. Lazetic, N. T. Young, J. I. Bell, J. H. Phillips, et al. 1998. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 391:795.
29. Brooks, A. G., F. Borrego, P. E. Posch. A. Patamawenu, C. J. Scorzelli, M. Ulbrecht, E. H. Weiss, and J. E. Coligan. 1999. Specific recognition of HLA-E, but not classical, HLA class I molecules by soluble CD94/NKG2A and NK cells. J. Immunol. 162:305.
30. Vance, R. E., J. R. Kraft, J. D. Altman, P. E. Jensen, and D. H. Raulet. 1998. Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b). J. Exp. Med. 188:1841.
31. Colonna, M., F., Navarro, T. Bellon, M. Llano, P. Garcia, J. Samaridis, L. Angman, M. Cella, and M. Lopez-Botet. 1997. A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J. Exp. Med. 186:1809.
32. Anderson, S. K., J. R. Ortaldo, and D. W. McVicar. 2001. The ever-expanding Ly49 gene family: repertoire and signaling. Immunol. Rev. 181:79.
33. Hanke, T., H. Takizawa, C. W. McMahon, D. H. Busch, E. G. Pamer, J. D. Miller, J. D. Altman, Y. Liu, D. Cado, F. A. Lemonnier, et al. 1999. Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity 11:67.
34. Maenaka, K., T. Juji, T. Nakayama, J. R. Wyer, G. F. Gao, T. Maenaka, N. R. Zaccai, A. Kikuchi, T. Yabe, K. Tokunaga, et al. 1999. Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties. J. Biol. Chem. 274:28329.
35. Chung, D. H., K. Natarajan, L. F. Boyd, J. Tormo, R. A. Mariuzza, W. M. Yokoyama, and D. H. Margulies. 2000. Mapping the ligand of the NK inhibitory receptor Ly49A on living cells. J. Immunol. 165:6922.
36. Vales-Gomez, M., H. T. Reyburn, R. A. Erskine, M. Lopez-Botet, and J. L. Strominger. 1999. Kinetics and peptide dependency of the binding of the inhibitory NK receptor CD94/NKG2-A and the activating receptor CD94/ NKG2-C to HLA-E. EMBO J. 18:4250.
37. Chapman, T. L., A. P. Heikeman, and P. J. Bjorkman. 1999. The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18. Immunity 11:603.
38. O'Callaghan, C. A., A. Cerwenka, B. E. Willcox, L. L. Lanier, and P. J. Bjorkman. 2001. Molecular competition for NKG2D: H60 and RAE1 compete unequally for NKG2D with dominance of H60. Immunity 15:201.
39. Carayannopoulos, L., O. Naidenko, J. Kinder, E. Ho, D. Fremont, and W. Yokoyama. 2002. Ligands for murine NKG2D display heterogeneous binding behavior. Eur. J. Immunol. 32:597.
40. Barber, L. D., L. Percival, N. M. Valiante, L. Chen, C. Lee, J. E. Gumperz, J. H. Phillips, L. L. Lanier, J. C. Bigge, R. B. Parekh, et al. 1996. The inter-locus recombinant HLA-B*4601 has high selectivity in peptide binding and functions characteristic of HLA-C. J. Exp. Med. 184:735.