Conserved and variable residues within the Bw4 motif of HLA-B make separable contributions to recognition by the NKB1 killer cell-inhibitory receptor

Journal of Immunology

Volumn 158, Issue 11, 1997, Pages 5237-5241

  Gumperz, Jenny E ^a   Barber, Linda D ^a   Valiante, Nicholas M ^a   Percival, Lucy ^a   Phillips, Joseph H ^b   Lanier, Lewis L ^b   Parham, Peter ^a,c  

^a STANFORD UNIVERSITY   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA B ANTIGEN; IMMUNOGLOBULIN RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR;

ARTICLE; BINDING SITE; CELL CLONE; GENETICS; HUMAN; IMMUNOLOGY; NATURAL KILLER CELL; NUCLEOTIDE SEQUENCE; SEQUENCE ANALYSIS;

BINDING SITES; CLONE CELLS; CONSERVED SEQUENCE; HLA-B ANTIGENS; HUMANS; KILLER CELLS, NATURAL; RECEPTORS, IMMUNOLOGIC; SEQUENCE ANALYSIS;

EID: 0031154293     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Barber, L. D., and P. Parham. 1993. Peptide binding to major histocompatibility complex molecules. Annu. Rev. Cell Biol. 9:163.
2. Storkus, W. J., J. Alexander, J. A. Payne, J. R. Dawson. and P. Cresswell. 1989. Reversal of natural killing susceptibility in target cells expressing transfected class I HLA genes. Proc. Natl. Acad. Sci. USA 86:2361.
3. Shimizu, Y., and R. DeMars. 1989. Demonstration by class I gene transfer that reduced susceptibility of human cells to natural killer cell-mediated lysis is inversely correlated with HLA class I antigen expression. Eur. J. Immunol. 19:447.
4. Gumperz, J. E., and P. Parham. 1995. The enigma of the natural killer cell. Nature 378:245.
5. Wagtmann, N., R. Biassoni, C. Cantoni, S. Verdiani, M. S. Malnati, M. Vitale, C. Bottino, L. Moretta, A. Moretta, and E. O. Long. 1995. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity 2:439.