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Volumn 9, Issue 6, 2002, Pages 319-328

Perinatal brain damage: Underlying mechanisms and neuroprotective strategies

Author keywords

Asphyxia; Brain damage; Excitotoxicity; Fetus; Intrauterine infection; Perinatal neuroprotection

Indexed keywords

ASPARTIC ACID; CALCIUM; CALCIUM CHANNEL; CYTOKINE; ENDONUCLEASE; ENDOTOXIN; FLUNARIZINE; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; GROWTH FACTOR; MAGNESIUM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; OXYGEN; OXYGEN RADICAL; PROTEINASE; TRIACYLGLYCEROL LIPASE;

EID: 0036850108     PISSN: 10715576     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1071-5576(02)00164-8     Document Type: Review
Times cited : (71)

References (68)
  • 2
    • 84965447364 scopus 로고
    • Course of lectures on the deformities of the human frame
    • Little W.J. Course of lectures on the deformities of the human frame. Lancet. i:1844;350-354.
    • (1844) Lancet , vol.1 , pp. 350-354
    • Little, W.J.1
  • 3
    • 0029892775 scopus 로고    scopus 로고
    • Bilateral cystic periventricular leukomalacia in the premature infant: Associated risk factors
    • Perlman J.M., Risser R., Broyles R.S. Bilateral cystic periventricular leukomalacia in the premature infant Associated risk factors . Pediatrics. 97:1996;822-827.
    • (1996) Pediatrics , vol.97 , pp. 822-827
    • Perlman, J.M.1    Risser, R.2    Broyles, R.S.3
  • 4
    • 0034692557 scopus 로고    scopus 로고
    • Chorioamnionitis as a risk factor for cerebral palsy: A meta-analysis
    • Wu Y.W., Colford J.M. Jr. Chorioamnionitis as a risk factor for cerebral palsy A meta-analysis . JAMA. 284:2000;1417-1424.
    • (2000) JAMA , vol.284 , pp. 1417-1424
    • Wu, Y.W.1    Colford J.M., Jr.2
  • 5
    • 0026183655 scopus 로고
    • Effects of acute asphyxia on brain energy metabolism in fetal guinea pigs near term
    • Berger R., Jensen A., Krieglstein J., Steigelman J.P. Effects of acute asphyxia on brain energy metabolism in fetal guinea pigs near term. J Dev Physiol. 16:1991;9-11.
    • (1991) J Dev Physiol , vol.16 , pp. 9-11
    • Berger, R.1    Jensen, A.2    Krieglstein, J.3    Steigelman, J.P.4
  • 6
    • 0003117828 scopus 로고
    • The multiple causes of ischemic brain damage: A speculative synthesis
    • J. Krieglstein, & H. Oberpichler-Schwenk. Stuttgart: Medpharm Scientific
    • Siesjö B.K., Katsura K., Pahlmark K., Smith M.-L. The multiple causes of ischemic brain damage A speculative synthesis . Krieglstein J., Oberpichler-Schwenk H., Pharmacology of cerebral ischemia. 1992;511-525 Medpharm Scientific, Stuttgart.
    • (1992) Pharmacology of cerebral ischemia , pp. 511-525
    • Siesjö, B.K.1    Katsura, K.2    Pahlmark, K.3    Smith, M.-L.4
  • 7
    • 0024596865 scopus 로고
    • The excitatory amino acid receptors: Their classes, pharmacology, and distinct properties in the function of the central nervous system
    • Monaghan D.T., Bridges R.J., Cotman C.W. The excitatory amino acid receptors Their classes, pharmacology, and distinct properties in the function of the central nervous system . Ann Rev Pharmacol Toxicol. 29:1989;365-402.
    • (1989) Ann Rev Pharmacol Toxicol , vol.29 , pp. 365-402
    • Monaghan, D.T.1    Bridges, R.J.2    Cotman, C.W.3
  • 8
    • 0023753142 scopus 로고
    • Calcium-mediated neurotoxicity: Relationship to specific channel types and role in ischemic damage
    • Choi D.W. Calcium-mediated neurotoxicity Relationship to specific channel types and role in ischemic damage . Trends Neurosci. 11:1988;465-469.
    • (1988) Trends Neurosci , vol.11 , pp. 465-469
    • Choi, D.W.1
  • 9
    • 0023934896 scopus 로고
    • The excitatory amino acid antagonist kynurenic acid administered after hypoxic ischemia in neonatal rat offers neuroprotection
    • Andine P., Lehmann A., Ellren K., et al. The excitatory amino acid antagonist kynurenic acid administered after hypoxic ischemia in neonatal rat offers neuroprotection. Neurosci Lett. 90:1988;208-212.
    • (1988) Neurosci Lett , vol.90 , pp. 208-212
    • Andine, P.1    Lehmann, A.2    Ellren, K.3
  • 10
    • 0023836750 scopus 로고
    • Glutamate antagonist therapy reduces neurologic deficits produced by focal central nervous system ischemia
    • Kochhar A., Zivin J.A., Lyden P.D., Mazzarella V. Glutamate antagonist therapy reduces neurologic deficits produced by focal central nervous system ischemia. Arch Neurol. 45:1988;148-153.
    • (1988) Arch Neurol , vol.45 , pp. 148-153
    • Kochhar, A.1    Zivin, J.A.2    Lyden, P.D.3    Mazzarella, V.4
  • 11
    • 0032848049 scopus 로고    scopus 로고
    • Pathophysiology of perinatal brain damage
    • Berger R., Garnier Y. Pathophysiology of perinatal brain damage. Brain Res Rev. 32:1999;107-134.
    • (1999) Brain Res Rev , vol.32 , pp. 107-134
    • Berger, R.1    Garnier, Y.2
  • 12
    • 0032403407 scopus 로고    scopus 로고
    • Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta
    • Bruno V., Battaglia G., Casabona G., Copani A., Caciagli F., Nicoletti F. Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta. J Neurosci. 18:1998;9594-9600.
    • (1998) J Neurosci , vol.18 , pp. 9594-9600
    • Bruno, V.1    Battaglia, G.2    Casabona, G.3    Copani, A.4    Caciagli, F.5    Nicoletti, F.6
  • 13
    • 17844376201 scopus 로고    scopus 로고
    • Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways
    • D'Onofrio M., Cuomo L., Battaglia G., et al. Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways. J Neurochem. 78:2001;435-445.
    • (2001) J Neurochem , vol.78 , pp. 435-445
    • D'Onofrio, M.1    Cuomo, L.2    Battaglia, G.3
  • 14
    • 0016719872 scopus 로고
    • Resuscitation of the monkey brain after one hour of complete ischemia. III. Indications of metabolic recovery
    • Kleihues P., Hossmann K.-A., Pegg A.E., Kobayashi K., Zimmermann V. Resuscitation of the monkey brain after one hour of complete ischemia. III. Indications of metabolic recovery. Brain Res. 95:1975;61-73.
    • (1975) Brain Res , vol.95 , pp. 61-73
    • Kleihues, P.1    Hossmann, K.-A.2    Pegg, A.E.3    Kobayashi, K.4    Zimmermann, V.5
  • 16
    • 0030028141 scopus 로고    scopus 로고
    • Ontogenetic differences in energy metabolism and inhibition of protein synthesis in hippocampal slices during in vitro ischemia and 24 h of recovery
    • Berger R., Djuricic B., Jensen A., Hossmann K.-A., Paschen W. Ontogenetic differences in energy metabolism and inhibition of protein synthesis in hippocampal slices during in vitro ischemia and 24 h of recovery. Dev Brain Res. 91:1996;281-291.
    • (1996) Dev Brain Res , vol.91 , pp. 281-291
    • Berger, R.1    Djuricic, B.2    Jensen, A.3    Hossmann, K.-A.4    Paschen, W.5
  • 17
    • 0000546314 scopus 로고
    • Protein synthesis after global cerebral ischemia and selective vulnerability
    • J. Krieglstein, & H. Oberpichler-Schwenk. Stuttgart: Medpharm Scientific
    • Hossmann K.-A., Widmann R., Wiessner Ch., Dux E., Djuricic B., Röhn G. Protein synthesis after global cerebral ischemia and selective vulnerability. Krieglstein J., Oberpichler-Schwenk H., Pharmacology of cerebral ischemia. 1992;289-299 Medpharm Scientific, Stuttgart.
    • (1992) Pharmacology of cerebral ischemia , pp. 289-299
    • Hossmann, K.-A.1    Widmann, R.2    Wiessner, Ch.3    Dux, E.4    Djuricic, B.5    Röhn, G.6
  • 18
    • 0034005443 scopus 로고    scopus 로고
    • Important role of 72-kd heat shock protein expression in the endothelial cell in acquisition of hypoxic-ischemic tolerance in the immature rat
    • Ikeda T., Ikenoue T., Xia X.Y., Xia Y.X. Important role of 72-kd heat shock protein expression in the endothelial cell in acquisition of hypoxic-ischemic tolerance in the immature rat. Am J Obstet Gynecol. 182:2000;380-386.
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 380-386
    • Ikeda, T.1    Ikenoue, T.2    Xia, X.Y.3    Xia, Y.X.4
  • 19
    • 0023655258 scopus 로고
    • Oxygen radicals stimulate intracellular proteolysis and lipid peroxidation by independent mechanisms in erythrocytes
    • Davies K.J.A., Goldberg A.L. Oxygen radicals stimulate intracellular proteolysis and lipid peroxidation by independent mechanisms in erythrocytes. J Biol Chem. 262:1987;8220-8226.
    • (1987) J Biol Chem , vol.262 , pp. 8220-8226
    • Davies, K.J.A.1    Goldberg, A.L.2
  • 20
    • 0011460290 scopus 로고
    • Radical scavengers: Penetration into brain following ischemia and reperfusion
    • J. Krieglstein, & H. Oberpichler-Schwenk. Stuttgart: Medpharm Scientific
    • Helfaer M.A., Kirsch J.R., Traystman R.J. Radical scavengers Penetration into brain following ischemia and reperfusion . Krieglstein J., Oberpichler-Schwenk H., Pharmacology of cerebral ischemia. 1994;297-309 Medpharm Scientific, Stuttgart.
    • (1994) Pharmacology of cerebral ischemia , pp. 297-309
    • Helfaer, M.A.1    Kirsch, J.R.2    Traystman, R.J.3
  • 21
    • 0027499214 scopus 로고
    • Allopurinol administered after inducing hypoxia/ischemia reduces brain injury in 7-day-old rats
    • Palmer C., Towfighi J., Roberts R.L., Heitjan D.F. Allopurinol administered after inducing hypoxia/ischemia reduces brain injury in 7-day-old rats. Pediatr Res. 33:1993;405-411.
    • (1993) Pediatr Res , vol.33 , pp. 405-411
    • Palmer, C.1    Towfighi, J.2    Roberts, R.L.3    Heitjan, D.F.4
  • 22
    • 0029444460 scopus 로고
    • Acute hypoxia induces elevation of ornithine decarboxylase activity in neonatal rat brain slices
    • Longo L.D., Packianathan S. Acute hypoxia induces elevation of ornithine decarboxylase activity in neonatal rat brain slices. Reprod Fertil Dev. 7:1995;385-389.
    • (1995) Reprod Fertil Dev , vol.7 , pp. 385-389
    • Longo, L.D.1    Packianathan, S.2
  • 23
    • 0030757114 scopus 로고    scopus 로고
    • Free radical-induced elevation of ornithine decarboxylase activity in developing rat brain slices
    • Saito K., Packianathan S., Longo L.D. Free radical-induced elevation of ornithine decarboxylase activity in developing rat brain slices. Brain Res. 763:1997;232-238.
    • (1997) Brain Res , vol.763 , pp. 232-238
    • Saito, K.1    Packianathan, S.2    Longo, L.D.3
  • 24
    • 0026497926 scopus 로고
    • Excitotoxic cell-death
    • Choi D.W. Excitotoxic cell-death. J Neurobiol. 23:1992;1261-1276.
    • (1992) J Neurobiol , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 25
    • 0026077959 scopus 로고
    • Glutamate, nitric oxide and cell-cell signaling in the nervous system
    • Garthwaite J. Glutamate, nitric oxide and cell-cell signaling in the nervous system. Trends Neurosci. 14:1991;60-67.
    • (1991) Trends Neurosci , vol.14 , pp. 60-67
    • Garthwaite, J.1
  • 26
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman J.S., Beckman T.W., Chen J., Marshall P.A., Freeman B.A. Apparent hydroxyl radical production by peroxynitrite Implications for endothelial injury from nitric oxide and superoxide . Proc Natl Acad Sci. 87:1990;1620-1624.
    • (1990) Proc Natl Acad Sci , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 27
    • 0028158140 scopus 로고
    • Inhibitor of nitric oxide synthesis reduces hypoxic/ischemic brain damage in the neonatal rat
    • Hamada Y., Hayakawa T., Hattori H., Mikawa H. Inhibitor of nitric oxide synthesis reduces hypoxic/ischemic brain damage in the neonatal rat. Pediatr Res. 35:1994;10-14.
    • (1994) Pediatr Res , vol.35 , pp. 10-14
    • Hamada, Y.1    Hayakawa, T.2    Hattori, H.3    Mikawa, H.4
  • 28
    • 0029865660 scopus 로고    scopus 로고
    • Neonatal mice lacking neuronal nitric oxide synthase are less vulnerable to hypoxic-ischemic injury
    • Ferriero D.M., Holtzman D.M., Black S.M., Sheldon R.A. Neonatal mice lacking neuronal nitric oxide synthase are less vulnerable to hypoxic-ischemic injury. Neurobiol Dis. 3:1996;64-71.
    • (1996) Neurobiol Dis , vol.3 , pp. 64-71
    • Ferriero, D.M.1    Holtzman, D.M.2    Black, S.M.3    Sheldon, R.A.4
  • 29
    • 0034755034 scopus 로고    scopus 로고
    • Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: Reduction by melatonin
    • Fulia F., Gitto E., Cuzzocrea S., et al. Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns Reduction by melatonin . J Pineal Res. 31:2001;343-349.
    • (2001) J Pineal Res , vol.31 , pp. 343-349
    • Fulia, F.1    Gitto, E.2    Cuzzocrea, S.3
  • 30
    • 0032056652 scopus 로고    scopus 로고
    • Free oxygen radicals - Predictors of neonatal outcome following perinatal asphyxia
    • Nangia S., Saili A., Dutta A.K., Batra S., Ray G.N. Free oxygen radicals - predictors of neonatal outcome following perinatal asphyxia. Indian J Pediatr. 65:1998;419-427.
    • (1998) Indian J Pediatr , vol.65 , pp. 419-427
    • Nangia, S.1    Saili, A.2    Dutta, A.K.3    Batra, S.4    Ray, G.N.5
  • 31
    • 0025906865 scopus 로고
    • Time course of intracellular edema and epileptiform activity following prenatal cerebral ischemia in sheep
    • Williams C.E., Gunn A., Gluckman P.D. Time course of intracellular edema and epileptiform activity following prenatal cerebral ischemia in sheep. Stroke. 22:1991;516-521.
    • (1991) Stroke , vol.22 , pp. 516-521
    • Williams, C.E.1    Gunn, A.2    Gluckman, P.D.3
  • 32
    • 0026497283 scopus 로고
    • Suppression of postischemic epileptiform activity with MK-801 improves neural outcome in fetal sheep
    • Tan W.K.M., Williams C.E., Gunn A.J., Mallard C.E., Gluckman P.D. Suppression of postischemic epileptiform activity with MK-801 improves neural outcome in fetal sheep. Ann Neurol. 32:1992;677-682.
    • (1992) Ann Neurol , vol.32 , pp. 677-682
    • Tan, W.K.M.1    Williams, C.E.2    Gunn, A.J.3    Mallard, C.E.4    Gluckman, P.D.5
  • 33
    • 0027498018 scopus 로고
    • Endonuclease activation following focal ischemic injury in the rat brain
    • Tominaga T., Kure S., Narisawa K., Yoshimotot T. Endonuclease activation following focal ischemic injury in the rat brain. Brain Res. 608:1993;21-26.
    • (1993) Brain Res , vol.608 , pp. 21-26
    • Tominaga, T.1    Kure, S.2    Narisawa, K.3    Yoshimotot, T.4
  • 34
    • 0032730930 scopus 로고    scopus 로고
    • Therapeutic targets for hypoxia-elicited pathways
    • Taylor C.T., Colgan S.P. Therapeutic targets for hypoxia-elicited pathways. Pharm Res. 16:1999;1498-1505.
    • (1999) Pharm Res , vol.16 , pp. 1498-1505
    • Taylor, C.T.1    Colgan, S.P.2
  • 35
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry N.A., Lazebnik Y. Caspases Enemies within . Science. 281:1998;1312-1316.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 36
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A., Dixit V.M. Death receptors Signaling and modulation . Science. 281:1998;1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 37
    • 0027275490 scopus 로고
    • A novel domain within the 55 kd TNF receptor signals cell death
    • Tartaglia L.A., Ayres T.M., Wong G.H., Goeddel D.V. A novel domain within the 55 kd TNF receptor signals cell death. Cell. 74:1993;845-853.
    • (1993) Cell , vol.74 , pp. 845-853
    • Tartaglia, L.A.1    Ayres, T.M.2    Wong, G.H.3    Goeddel, D.V.4
  • 38
    • 0031933376 scopus 로고    scopus 로고
    • Effects of chronic placental insufficiency on brain development in fetal sheep
    • Mallard E.C., Rees S., Stringer M., Cock M.L., Harding R. Effects of chronic placental insufficiency on brain development in fetal sheep. Pediatr Res. 43:1998;262-270.
    • (1998) Pediatr Res , vol.43 , pp. 262-270
    • Mallard, E.C.1    Rees, S.2    Stringer, M.3    Cock, M.L.4    Harding, R.5
  • 41
    • 0030924241 scopus 로고    scopus 로고
    • Maternal intrauterine infection, cytokines, and brain damage in the preterm infant
    • Dammann O., Leviton A. Maternal intrauterine infection, cytokines, and brain damage in the preterm infant. Pediatr Res. 42:1997;1-8.
    • (1997) Pediatr Res , vol.42 , pp. 1-8
    • Dammann, O.1    Leviton, A.2
  • 43
    • 0034037785 scopus 로고    scopus 로고
    • Fetal exposure to an intra-amniotic inflammation and the development of cerebral palsy at the age of three years
    • Yoon B.H., Romero R., Park J.S., et al. Fetal exposure to an intra-amniotic inflammation and the development of cerebral palsy at the age of three years. Am J Obstet Gynecol. 182:2000;675-681.
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 675-681
    • Yoon, B.H.1    Romero, R.2    Park, J.S.3
  • 44
    • 0035010107 scopus 로고    scopus 로고
    • Endotoxemia severely affects circulation during normoxia and asphyxia in immature fetal sheep
    • Garnier Y., Coumans A., Berger R., Jensen A., Hasaart T.H.M. Endotoxemia severely affects circulation during normoxia and asphyxia in immature fetal sheep. J Soc Gynecol Investig. 8:2001;134-142.
    • (2001) J Soc Gynecol Investig , vol.8 , pp. 134-142
    • Garnier, Y.1    Coumans, A.2    Berger, R.3    Jensen, A.4    Hasaart, T.H.M.5
  • 45
    • 0033804749 scopus 로고    scopus 로고
    • Lipopolysaccharides do not alter energy metabolism and protein synthesis in an in vitro model of fetal cerebral ischemia
    • Berger R., Garnier Y., Pfeiffer D., Jensen A. Lipopolysaccharides do not alter energy metabolism and protein synthesis in an in vitro model of fetal cerebral ischemia. Pediatr Res. 48:2000;531-535.
    • (2000) Pediatr Res , vol.48 , pp. 531-535
    • Berger, R.1    Garnier, Y.2    Pfeiffer, D.3    Jensen, A.4
  • 46
    • 4243398563 scopus 로고    scopus 로고
    • TNF-α induces cell death in primary cultures of oligodendrocyte progenitors
    • Feldhaus B., Dietzel I.D., Berger R. TNF-α induces cell death in primary cultures of oligodendrocyte progenitors. J Soc Gynecol Investig. 8:2001;248A.
    • (2001) J Soc Gynecol Investig , vol.8
    • Feldhaus, B.1    Dietzel, I.D.2    Berger, R.3
  • 48
    • 0035134439 scopus 로고    scopus 로고
    • Type 1/Type 2 immunity in infectious diseases
    • Spellberg B., Edwards J.E. Jr. Type 1/Type 2 immunity in infectious diseases. Clin Infect Dis. 32:2001;76-102.
    • (2001) Clin Infect Dis , vol.32 , pp. 76-102
    • Spellberg, B.1    Edwards J.E., Jr.2
  • 49
    • 0017180317 scopus 로고
    • Origin of intraventricular haemorrhage in the preterm infant
    • Hambleton G., Wigglesworth J.S. Origin of intraventricular haemorrhage in the preterm infant. Arch Dis Child. 51:1976;651-659.
    • (1976) Arch Dis Child , vol.51 , pp. 651-659
    • Hambleton, G.1    Wigglesworth, J.S.2
  • 50
    • 0028888763 scopus 로고
    • Germinal matrix microvascular maturation correlates inversely with the risk period for neonatal intraventricular hemorrhage
    • Ment L.R., Stewart W.B., Ardito T.A., Madri J.A. Germinal matrix microvascular maturation correlates inversely with the risk period for neonatal intraventricular hemorrhage. Brain Res Dev Brain Res. 84:1995;142-149.
    • (1995) Brain Res Dev Brain Res , vol.84 , pp. 142-149
    • Ment, L.R.1    Stewart, W.B.2    Ardito, T.A.3    Madri, J.A.4
  • 51
    • 0018843851 scopus 로고
    • Failure of autoregulation and intraventricular haemorrhage in preterm infants
    • Milligran D.W. Failure of autoregulation and intraventricular haemorrhage in preterm infants. Lancet. i:1980;896-898.
    • (1980) Lancet , vol.1 , pp. 896-898
    • Milligran, D.W.1
  • 52
    • 0023680296 scopus 로고
    • Coagulation abnormalities in low birth weight infants with peri-intraventricular hemorrhage
    • Amato M., Fauchere J.C., Hermann U. Jr. Coagulation abnormalities in low birth weight infants with peri-intraventricular hemorrhage. Neuropediatrics. 19:1988;154-157.
    • (1988) Neuropediatrics , vol.19 , pp. 154-157
    • Amato, M.1    Fauchere, J.C.2    Hermann U., Jr.3
  • 53
    • 0031471023 scopus 로고    scopus 로고
    • Brain injury in the premature infant - From pathogenesis to prevention
    • Volpe J.J. Brain injury in the premature infant - from pathogenesis to prevention. Brain Dev. 19:1997;519-534.
    • (1997) Brain Dev , vol.19 , pp. 519-534
    • Volpe, J.J.1
  • 54
    • 0026402949 scopus 로고
    • Fetal circulatory responses to oxygen lack
    • Jensen A., Berger R. Fetal circulatory responses to oxygen lack. J Dev Physiol. 16:1991;181-207.
    • (1991) J Dev Physiol , vol.16 , pp. 181-207
    • Jensen, A.1    Berger, R.2
  • 55
    • 0027735370 scopus 로고
    • Hypothermia as a potential treatment for cerebral ischemia
    • Maher J., Hachinski V. Hypothermia as a potential treatment for cerebral ischemia. Cerebrovasc Brain Metab Rev. 5:1993;277-300.
    • (1993) Cerebrovasc Brain Metab Rev , vol.5 , pp. 277-300
    • Maher, J.1    Hachinski, V.2
  • 56
    • 0023554153 scopus 로고
    • Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury
    • Busto R., Dietrich W.D., Globus M.Y., Valdes I., Scheinberg P., Ginsberg M.D. Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J Cereb Blood Flow Metab. 7:1987;729-738.
    • (1987) J Cereb Blood Flow Metab , vol.7 , pp. 729-738
    • Busto, R.1    Dietrich, W.D.2    Globus, M.Y.3    Valdes, I.4    Scheinberg, P.5    Ginsberg, M.D.6
  • 57
    • 0026653468 scopus 로고
    • Protective effect of brain hypothermia on behavior and histopathology following global cerebral ischemia in rats
    • Green E.J., Dietrich W.D., van Dijk F., et al. Protective effect of brain hypothermia on behavior and histopathology following global cerebral ischemia in rats. Brain Res. 580:1992;197-204.
    • (1992) Brain Res , vol.580 , pp. 197-204
    • Green, E.J.1    Dietrich, W.D.2    Van Dijk, F.3
  • 58
    • 0032515389 scopus 로고    scopus 로고
    • Effect of mild hypothermia during and after transient in vitro ischemia on metabolic disturbances in hippocampal slices at different stages of development
    • Berger R., Jensen A., Hossmann K.-A., Paschen W. Effect of mild hypothermia during and after transient in vitro ischemia on metabolic disturbances in hippocampal slices at different stages of development. Dev Brain Res. 105:1998;67-77.
    • (1998) Dev Brain Res , vol.105 , pp. 67-77
    • Berger, R.1    Jensen, A.2    Hossmann, K.-A.3    Paschen, W.4
  • 59
    • 0034887861 scopus 로고    scopus 로고
    • Effects of mild hypothermia on metabolic disturbances in fetal hippocampal slices after oxygen/glucose deprivation depend on depth and time delay of cooling
    • Garnier Y., Pfeiffer D., Jensen A., Berger R. Effects of mild hypothermia on metabolic disturbances in fetal hippocampal slices after oxygen/glucose deprivation depend on depth and time delay of cooling. J Soc Gynecol Investig. 8:2001;198-205.
    • (2001) J Soc Gynecol Investig , vol.8 , pp. 198-205
    • Garnier, Y.1    Pfeiffer, D.2    Jensen, A.3    Berger, R.4
  • 60
    • 0031789208 scopus 로고    scopus 로고
    • Neuroprotection with prolonged head cooling started before postischemic seizures in fetal sheep
    • Gunn A.J., Gunn T.R., Gunning M.I., Williams C.E., Gluckman P.D. Neuroprotection with prolonged head cooling started before postischemic seizures in fetal sheep. Pediatrics. 102:1998;1098-1106.
    • (1998) Pediatrics , vol.102 , pp. 1098-1106
    • Gunn, A.J.1    Gunn, T.R.2    Gunning, M.I.3    Williams, C.E.4    Gluckman, P.D.5
  • 61
    • 0031034474 scopus 로고    scopus 로고
    • Dramatic neuronal rescue with prolonged selective head cooling after ischemia in fetal lambs
    • Gunn A.J., Gunn T.R., de Haan H.H., Williams C.E., Gluckman P.D. Dramatic neuronal rescue with prolonged selective head cooling after ischemia in fetal lambs. J Clin Invest. 99:1997;248-256.
    • (1997) J Clin Invest , vol.99 , pp. 248-256
    • Gunn, A.J.1    Gunn, T.R.2    De Haan, H.H.3    Williams, C.E.4    Gluckman, P.D.5
  • 62
    • 0031661767 scopus 로고    scopus 로고
    • Selective head cooling in newborn infants after perinatal asphyxia: A safety study
    • Gunn A.J., Gluckman P.D., Gunn T.R. Selective head cooling in newborn infants after perinatal asphyxia A safety study . Pediatrics. 102:1998;885-892.
    • (1998) Pediatrics , vol.102 , pp. 885-892
    • Gunn, A.J.1    Gluckman, P.D.2    Gunn, T.R.3
  • 64
    • 0031868298 scopus 로고    scopus 로고
    • Low dose flunarizine protects the fetal brain from ischemic injury in sheep
    • Berger R., Lehmann T., Karcher J., Garnier Y., Jensen A. Low dose flunarizine protects the fetal brain from ischemic injury in sheep. Pediatr Res. 44:1998;1-6.
    • (1998) Pediatr Res , vol.44 , pp. 1-6
    • Berger, R.1    Lehmann, T.2    Karcher, J.3    Garnier, Y.4    Jensen, A.5
  • 65
    • 0032469570 scopus 로고    scopus 로고
    • Low dose flunarizine does not affect short term fetal circulatory responses to acute asphyxia in sheep near term
    • Garnier Y., Berger R., Pfeiffer D., Jensen A. Low dose flunarizine does not affect short term fetal circulatory responses to acute asphyxia in sheep near term. Reprod Fertil Dev. 10:1998;405-411.
    • (1998) Reprod Fertil Dev , vol.10 , pp. 405-411
    • Garnier, Y.1    Berger, R.2    Pfeiffer, D.3    Jensen, A.4
  • 66
    • 0028939566 scopus 로고
    • Can magnesium sulfate reduce the risk of cerebral palsy in very low birthweight infants?
    • Nelson K.B., Grether J.K. Can magnesium sulfate reduce the risk of cerebral palsy in very low birthweight infants? Pediatrics. 95:1995;263-269.
    • (1995) Pediatrics , vol.95 , pp. 263-269
    • Nelson, K.B.1    Grether, J.K.2
  • 67
    • 0029902517 scopus 로고    scopus 로고
    • Prenatal magnesium sulfate exposure and risk for cerebral palsy or mental retardation among very low-birth-weight children aged 3 to 5 years
    • Schendel D.E., Berg C.J., Yeargin-Allsopp M., Boyle C.A., Decoufle P. Prenatal magnesium sulfate exposure and risk for cerebral palsy or mental retardation among very low-birth-weight children aged 3 to 5 years. JAMA. 276:1996;1805-1810.
    • (1996) JAMA , vol.276 , pp. 1805-1810
    • Schendel, D.E.1    Berg, C.J.2    Yeargin-Allsopp, M.3    Boyle, C.A.4    Decoufle, P.5
  • 68
    • 0036130762 scopus 로고    scopus 로고
    • Neuroprotective effects of magnesium on metabolic disturbances in fetal hippocampal slices after oxygen-glucose deprivation
    • Garnier Y., Middelanis J., Jensen A., Berger R. Neuroprotective effects of magnesium on metabolic disturbances in fetal hippocampal slices after oxygen-glucose deprivation. J Soc Gynecol Investig. 9:2002;86-92.
    • (2002) J Soc Gynecol Investig , vol.9 , pp. 86-92
    • Garnier, Y.1    Middelanis, J.2    Jensen, A.3    Berger, R.4


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