Crystal structure and substrate binding modeling of the uroporphyrinogen-III decarboxylase from Nicotiana tabacum: Implications for the catalytic mechanism

Journal of Biological Chemistry

Volumn 276, Issue 47, 2001, Pages 44108-44116

  Martins, Berta M ^a   Grimm, Bernhard ^b,c   Mock, Hans Peter ^c   Huber, Robert ^a   Messerschmidt, Albrecht ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c LEIBNIZ INSTITUTE OF PLANT GENETICS AND CROP PLANT RESEARCH IPK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOSYNTHESIS; CARBOXYLATION; CATALYSIS; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DIMERS; ENZYME KINETICS; ESCHERICHIA COLI;

ENZYMATIC CATALYSIS; MOLECULAR MODELING;

BIOCHEMISTRY;

ARGININE; ASPARTIC ACID; CHLOROPHYLL; COPROPORPHYRINOGEN; HEME; HISTIDINE; SERINE; TYROSINE; UROPORPHYRINOGEN DECARBOXYLASE;

ARTICLE; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; DECARBOXYLATION; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TOBACCO; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI; INSERTION SEQUENCES; NICOTIANA; NICOTIANA TABACUM;

AMINO ACID SEQUENCE; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TOBACCO; UROPORPHYRINOGEN DECARBOXYLASE;

EID: 0035941294     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104759200     Document Type: Article

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