The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor

Nature Structural Biology

Volumn 9, Issue 1, 2002, Pages 27-31

  Korolev, Sergey ^a   Ikeguchi, Yoshihiko ^b   Skarina, Tatiana ^c   Beasley, Steven ^c   Arrowsmith, Cheryl ^c   Edwards, Aled ^c,d   Joachimiak, Andrzej ^a   Pegg, Anthony E ^b   Savchenko, Alexei ^c  

^a ARGONNE NATIONAL LABORATORY   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c Banting and Best Department of Medical Research   (Canada)

^d UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

POLYAMINE; SPERMIDINE; SPERMIDINE SYNTHASE;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME STRUCTURE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN FOLDING; PROTON TRANSPORT; STEREOCHEMISTRY; THERMOTOGA MARITIMA;

ADENOSINE; AMINO ACID SEQUENCE; APOENZYMES; BINDING SITES; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; POLYAMINES; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SPERMIDINE SYNTHASE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THERMOTOGA MARITIMA;

THERMOTOGA; THERMOTOGA MARITIMA;

EID: 0036142291     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb737     Document Type: Article

References (30)