Crystal structure of precorrin-8x methyl mutase

Structure

Volumn 9, Issue 7, 2001, Pages 587-596

  Shipman, Lance W ^a   Li, Ding ^a   Roessner, Charles A ^a   Scott, A I ^a   Sacchettini, James C ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Precorrin 8x; Sigmatropic rearrangement; Vitamin B12

Indexed keywords

ENZYME; HISTIDINE; METHYL GROUP; PRECORRIN 8X METHYL MUTASE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTON TRANSPORT; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; INTRAMOLECULAR TRANSFERASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; UROPORPHYRINS;

EID: 0034941726     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00618-9     Document Type: Article

References (33)

1. 12 - Mechanistic studies on the transfer of a methyl group from C-11 to C-12 and incorporation of O-18
2. Biosynthesis of porphyrins and related macrocycles. Part 29. Synthesis and chemistry of 2,2-disubstituted 2H-pyrroles (pyrrolenines)
3. Genetically engineered synthesis of precorrin-6-x and the complete corrinoid, hydrogenobyrinic acid
4. Hydrogenobyrinic acid: Isolation, biosynthesis, and function
5. The final step in the biosynthesis of hydrogenobyrinic acid is catalyzed by the cobH gene product with precorrin-8x as the substrate
6. PHD: Predicting one-dimensional protein structure by profile-based neural networks
7. Expression of 9 Salmonella typhimurium enzymes for cobinamide synthesis. Identification of the 11-methyl and 20-methyl transferases of corrin biosynthesis
8. 12) biosynthetic genes of Salmonella typhimurium
9. The anatomy and taxonomy of protein structure
10. Protein folds and families: Sequence and structure alignments
11. 12-binding domains of methionine synthase
12. 12 radicals are generated: The crystal structure of methylmalonyl-coenzyme A mutase at 2 Å resolution
13. The X-ray structure of a cobalamin biosynthetic enzyme, cobalt-precorrin-4 methyltransferase
14. Common chelatase design in the branched tetrapyrrole pathways of heme and anaerobic cobalamin synthesis
15. Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase (CobU) complexed with GMP: Evidence for a substrate-induced transferase active site
16. Identification and quantitation of corrinoid precursors of cobalamin from Pseudomonas denitrificans by high-performance liquid chromatography
17. 12: Structure of precorrin-6x octamethyl ester
18. 12: Structural studies on precorrin-8x, an octamethylated intermediate and the structure of its stable tautomer
19. The biological synthesis of cholesterol
20. 12: Discovery of the enzymes for oxidative ring contraction and insertion of the fourth methyl group
21. A multifunctional plasmid for protein expression by ECPCR: Overproduction of the p50 subunit of NF-KB
22. Processing of X-ray diffraction data collected in oscillation mode
23. Crystallography & NMR system: A new software suite for macromolecular structure determination
24. PHASES-95: A program package for the processing and analysis of diffraction data from macromolecules
25. XtalView/Xfit - A versatile program for manipulating atomic coordinates and electron density
26. The CCP4 (Collaborative Computational Project Number 4) suite: Programs for protein crystallography
27. Automated structure solution for MIR and MAD
28. Phase combination and cross validation in iterated density modification calculations
29. Improved methods for binding protein models in electron density maps and the location of errors in these models
30. PROCHECK: A program to check the stereochemical quality of protein structures
31. SETOR: Hardware lighted three dimensional solid model representations of macromolecules