Urotensin-II regulates intracellular calcium in dissociated rat spinal cord neurons

Journal of Neurochemistry

Volumn 83, Issue 4, 2002, Pages 879-884

  Filipeanu, Catalin M ^a   Brailoiu, Eugen ^a   Le Dun, Siok ^a   Dun, Nae J ^a  

^a East Tennessee State University   (United States)

Author keywords

Ca2+ i; Ca2+ influx; Protein kinase A; Spinal neurons; Urotensin II

Indexed keywords

4 O METHYLPHORBOL 13 ACETATE 12 MYRISTATE; BISINDOLYLMALEIMIDE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CHOLINE ACETYLTRANSFERASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DERIVATIVE; FURA 2; KT 5720; KT 5823; OMEGA CONOTOXIN GVIA; OMEGA CONOTOXIN GVIIC; UNCLASSIFIED DRUG; UROTENSIN II; VERAPAMIL;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME MODIFICATION; EXTRACELLULAR SPACE; MICROFLUOROMETRY; MOTONEURON; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD NERVE CELL;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, N-TYPE; CELLS, CULTURED; CHOLINE O-ACETYLTRANSFERASE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLUORESCENT DYES; FURA-2; INTRACELLULAR FLUID; MOTOR NEURONS; PROTEIN KINASE C; RATS; SPINAL CORD; UROTENSINS;

ANIMALIA;

EID: 0036846134     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01196.x     Document Type: Article

References (37)

1. Ames R. S., Sarau H. M., Chambers J. K., Willette R. N., Aiyar N. V., Romanic A. M., Louden C. S., Foley J. J., Sauermelch C. F., Coatney R. W., Ao Z., Disa J., Holmes S. D., Stadel J. M., Martin J. D., Liu W.-S., Glover G. I., Wilson S., McNulty D. E., Ellis C. E., Elshourbagy N. A., Shabon U., Trill J. J., Hay D. W. P., Ohlstein E. H., Bergsma D. J. and Douglas S. A. (1999) Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Nature 401, 282-286.
2. Arslan G., Filipeanu C. M., Irenius E., Kull B., Clementi E., Allgaier C., Erlinge D. and Fredholm B. B. (2000) P2Y receptors contribute to ATP-induced increases in intracellular calcium in differentiated but not undifferentiated PC12 cells. Neuropharmacology 39, 482-496.
3. Bottrill F. E., Douglas S. A., Hiley C. R. and White R. (2000) Human urotensin-II is an endothelium-dependent vasodilator in rat small arteries. Br. J. Pharmacol. 130, 1865-1870.
4. Camarda V., Rizzi A., Calo G., Gendron G., Perron S. I., Kostenis E., Zamboni P., Mascoli F. and Regoli D. (2002) Effects of human urotensin II in isolated vessels of various species; comparison with other vasoactive agents. Naunyn-Schmiedeberg's Arch. Pharmacol. 365, 141-149.
5. Coulouarn Y., Jegou S., Tostivint H., Vaudry H. and Lihrmann I. (1999) Cloning, sequence analysis and tissue distribution of the mouse and rat urotensin II precursors. FEBS Lett. 457, 28-32.
6. Douglas S. A. and Ohlstein E. H. (2000) Human urotensin-II, the most potent mammalian vasoconstrictor identified to date, as a therapeutic target for the management of cardiovascular disease. Trends Cardiovasc. Med. 10, 229-237.
7. Douglas S. A., Ashton D. J., Sauermelch C. F., Coatney R. W., Ohlstein D. H., Ruffolo M. R., Ohlstein E. H., Aiyar N. V. and Willette R. N. (2000) Human urotensin-II is a potent vasoactive peptide: Pharmacological characterization in the rat, mouse, dog and primate. J. Cardiovasc. Pharmacol. 36, S163-S166.
8. Dun S. L., Brailoiu G. C., Yang J., Chang J. K. and Dun N. J. (2001) Urotensin II-immunoreactivity in the brainstem and spinal cord of the rat. Neurosci. Lett. 305, 9-12.
9. i homeostasis in MRP1 over-expressing cells. FEBS Lett. 474, 107-110.
10. Filipeanu C. M., Henning R. H., Nelemans S. A. and de Zeeuw D. (2001) Intracellular angiotensin II: From myth to reality? J. Renin Angiotensin Aldosterone Syst. 2, 219-226.
11. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440-3450.
12. i elevation in DRG neurons of neonatal rats. J. Neurosci. Res. 66, 592-600.
13. Kase H., Iwahashi K., Nakanishi S., Matsuda Y., Yamada K., Takahashi M., Murakata C., Sato A. and Kaneko M. (1987) K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem. Biophys. Res. Commun. 142, 436-440.
14. Katano Y., Ishihata A., Aita T., Ogaki T. and Horie T. (2000) Vasodilator effect of urotensin II, one of the most potent vasoconstricting factors, on rat coronary arteries. Eur. J. Pharmacol. 402, R5-R7.
15. Liu Q., Pong S. S., Zeng Z., Zhang Q., Howard A. D., Williams D. L. Jr, Davidoff M., Wang R., Austin C. P., McDonald T. P., Bai C., George S. R., Evans J. F. and Caskey C. T. (1999) Identification of urotensin II as the endogenous ligand for the orphan G proteincoupled receptor GPR14. Biochem. Biophys. Res. Commun. 266, 174-178.
16. Mellor H. and Parker P. J. (1998) The extended protein kinase C superfamily. Biochem. J. 332, 281-292.
17. Mynlieff M. and Beam K. G. (1992) Characterization of voltage-dependent calcium currents in mouse motoneurons. J. Neurophysiol. 68, 85-92.
18. Nishizuka Y. (1995) Protein kinase C and lipid signaling for sustained cellular responses. FASEB J. 9, 484-496.
19. Pearson D., Shively J. E., Clark B. R., Geschwind I. I., Barkley M., Nishioka R. S. and Bern H. A. (1980) Urotensin II: A somatostatin-like peptide in the caudal neurosecretory system of fishes. Proc. Natl Acad. Sci. USA 77, 5021-5024.
20. Rothermel J. D. and Parker-Bothelo L. H. (1988) A mechanistic and kinetic analysis of the interactions of the diastereoisomers of adenosine 3′,5′-(cyclic) phosphorothioate with purified cyclic AMP-dependent protein kinase. Biochem. J. 25, 757-762.
21. Santschi L., Reyes-Harde M. and Stanton P. K. (1999) Chemically induced, activity-independent LTD elicited by simultaneous activation of PKG and inhibition of PKA. J. Neurophysiol. 82, 1577-1589.
22. Sauzeau V., Le Mellionnec E., Bertoglio J., Scalbert E., Pacaud P. and Loirand G. (2001) Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase. Circ. Res. 88, 1102-1104.
23. Sawada M. and Ichinose M. (1999) Potentiation of GABA (A) receptor-mediated Cl-current by urotensin peptides in identified Aplysia neurons. J. Neurosci. Res. 56, 547-552.
24. Scamps F., Valentin S., Dayanithi G. and Valmier J. (1998) Calcium channel subtypes responsible for voltage-gated intracellular calcium elevations in embryonic rat motoneurons. Neurosci. 87, 719-730.
25. Schwede F., Maronde E., Genieser H. and Jastorff B. (2000) Cyclic nucleotide analogs as biochemical tools and prospective drugs. Pharmacol. Ther. 87, 199-226.
26. Skofitsch G. and Jacobowitz D. M. (1985) Calcitonin gene-related peptide coexists with substance P in capsaicin sensitive neurons and sensory ganglia of the rat. Peptides 6, 747-754.
27. Smolenski A., Burkhardt A. M., Eigenthaler M., Butt E., Gambaryan S., Lohmann S. M. and Walter U. (1998) Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects. Naunyn-Schmiedeberg's Arch. Pharmacol. 358, 134-139.
28. Tang S. H. and Sharp G. W. (1998) Atypical protein kinase C isozyme zeta mediates carbachol-stimulated insulin secretion in RINm5F cells. Diabetes 47, 905-912.
29. Tarabal O., Caldero J., Llado J., Oppenheim R. W. and Esquerda J. E. (2001) Long-lasting aberrant tubulovesicular membrane inclusions accumulate in developing motoneurons after a sublethal excitotoxic insult: A possible model for neuronal pathology in neurodegenerative disease. J. Neurosci. 21, 8072-8081.
30. Toullec D., Pianetti P., Coste H., Bellevergue P., Grand-Perret T., Ajakane M., Baudet V., Boissin P., Boursier E., Loriolle F., Duhamel L., Charon D. and Kirilovsky J. (1991) The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266, 15771-15781.
31. Trafton J. A., Abbadie C. and Basbaum A. I. (2001) Differential contribution of substance P and neurokinin A to spinal cord neurokinin-1 receptor signaling in the rat. J. Neurosci. 21, 3656-3664.
32. Watanabe T., Pakala R., Katagiri T. and Benedict C. R. (2001) Synergistic effect of urotensin II with mildly oxidized LDL on DNA synthesis in vascular smooth muscle cells. Circulation 104, 16-18.
33. West A. E., Chen W. G., Dalva M. B., Dolmetsch R. E., Komhauser J. M., Shaywitz A. J., Takasu M. A., Tao X. and Greenberg M. E. (2001) Calcium regulation of neuronal gene expression. Proc. Natl Acad. Sci. USA 98, 11024-11031.
34. 2+ channel subtypes on rat spinal motor neurons, intemeurons, and nerve terminals. J. Neurosci. 18, 6319-6330.
35. Yashpal K., Pitcher G. M., Parent A., Quirion R. and Coderre T. J. (1995) Noxious thermal and chemical stimulation induce increases in 3H-phorbol 12,13-dibutyrate binding in spinal cord dorsal horn as well as persistent pain and hyperalgesia, which is reduced by inhibition of protein kinase C. J. Neurosci. 15, 3263-3272.
36. Zhang Y., Li J., Cao J., Chen J., Yang J., Du Zhang Z. J. and Tang C. (2002) Effect of chronic hypoxia on contents of urotensin II and its functional receptors in rat myocardium. Heart Vessels 16, 64-68.
37. Zhou Q. L., Strichartz G. and Davar G. (2001) Endothelin-1 activates ET (A) receptors to increase intracellular calcium in model sensory neurons. Neuroreport 12, 3853-3857.