Urotensin II-immunoreactivity in the brainstem and spinal cord of the rat

Neuroscience Letters

Volumn 305, Issue 1, 2001, Pages 9-12

  Dun, S L ^a   Brailoiu, G C ^a   Yang, J ^b   Chang, J K ^b   Dun, N J ^a  

^a East Tennessee State University   (United States)

^b PHOENIX PHARMACEUTICALS INC   (United States)

Author keywords

Abducens nucleus; Choline acetyltransferase; Facial motor nucleus; Hypoglossal nucleus; Nucleus ambiguus; Trigeminal motor nucleus; Ventral horn motoneurons

Indexed keywords

CHOLINE ACETYLTRANSFERASE; CHOLINE ACETYLTRANSFERASE ANTISERUM; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; UROTENSIN II; UROTENSIN II ANTISERUM; ANTISERUM;

ABDUCENS NUCLEUS; AMBIGUUS NUCLEUS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CONTROLLED STUDY; CROSS REACTION; FACIAL NERVE NUCLEUS; HYPOGLOSSAL NUCLEUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MOTONEURON NUCLEUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SPINAL CORD VENTRAL HORN; TRIGEMINAL NUCLEUS; ANIMAL EXPERIMENT; TISSUE DISTRIBUTION; VAGUS NERVE NUCLEUS;

ANIMALS; BRAIN STEM; CHOLINE O-ACETYLTRANSFERASE; IMMUNOHISTOCHEMISTRY; LUMBOSACRAL REGION; MALE; MOTOR NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; TISSUE DISTRIBUTION; UROTENSINS;

EID: 0035827466     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)01804-3     Document Type: Article

References (12)

1. Ames R.S., Sarau H.M., Chambers J.K., Willette R.N., Aiyar N.V., Romanic A.M., Louden C.S., Foley J.J., Sauermelch C.F., Coatney R.W., Ao Z., Disa J., Holmes S.D., Stadel J.M., Martin J.D., Liu W.-S., Glover G.I., Wilson S., McNulty D.E., Ellis C.E., Elshourbagy N.A., Shabon U., Trill J.J., Hay D.W.P., Ohlstein E.H., Bergsma D.J., Douglas S.A. Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Nature. 401:1999;282-286.
2. Chartrel N., Conlon J.M., Collin F., Braun B., Waugh D., Vallarino M., Lahrichi S.L., Rivier J.E., Vaudry H. Urotensin II in the central nervous system of the frog Rana ridibunda: immunohistochemical localization and biochemical characterization. J. Comp. Neurol. 364:1996;324-339.
3. Conlon J.M. Singular contributions of fish neuroendocrinology to mammalian regulatory peptide research. Regul. Pept. 93:2000;3-12.
4. Coulouarn Y., Jégou S., Tostivint H., Vaudry H., Lihrmann I. Cloning, sequence analysis and tissue distribution of the mouse and rat urotensin II precursors. FEBS Lett. 457:1999;28-32.
5. Coulouarn Y., Lihrmann I., Jégou S., Anouar Y., Tostivint H., Beauvillain J.C., Conlon J.M., Bern H.A., Vaudry H. Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals intense expression of the urotensin II gene in motoneurons of the spinal cord. Proc. Natl. Acad. Sci. USA. 95:1998;15803-15808.
6. Douglas S.A., Sulpizio A.C., Piercy V., Sarau H.M., Ames R.S., Aiyar N.V., Ohlstein E.H., Willette R.N. Differential vasoconstrictor activity of human urotensin-II in vascular tissue isolated from the rat, mouse, dog, pig, marmoset and cynomolgus monkey. Br. J. Pharmacol. 131:2000;1262-1274.
7. Dun N.J., Dun S.L., Wu S.Y., Förstermann U., Schmidt H.H.H.W., Tseng L.F. Nitric oxide synthase immunoreactivity in the rat, mouse, cat and squirrel monkey spinal cord. Neuroscience. 54:1993;843-857.
8. Liu Q., Pong S.S., Zeng Z., Zhang Q., Howard A.D., Williams D.L. Jr., Davidoff M., Wang R., Austin C.P., McDonald T.P., Bai C., George S.R., Evans J.F., Caskey C.T. Identification of urotensin II as the endogenous ligand for the orphan G-protein-coupled receptor GPR14. Biochem. Biophys. Res. Commun. 266:1999;174-178.
9. Maguire J.J., Kuc R.E., Davenport A.P. Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1. Br. J. Pharmacol. 131:2000;441-446.
10. Mori M., Sugo T., Abe M., Shimomura Y., Kurihara M., Kitada C., Kikuchi K., Shintani Y., Kurokawa T., Onda H., Nishimura O., Fujino M. Urotensin II is the endogenous ligand of a G-protein-coupled orphan receptor SENR (GPR14). Biochem. Biophys. Res. Commun. 265:1999;123-129.
11. Nothacker H.P., Wang Z., McNeill A.M., Saito Y., Merten S., O'Dowd B., Duckles S.P., Civelli O. Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction. Nature Cell Biol. 1:1999;383-385.
12. Pearson D., Shively J.E., Clark B.R., Geschwind I.I., Barkley M., Nishioka R.S., Bern H.A. Urotensin II: a somatostatin-like peptide in the caudal neurosecretory system of fishes. Proc. Natl. Acad. Sci., USA. 77:1980;5021-5024.