Pathogenic Role of Oxidative Stress in Vascular Angiotensin-Converting Enzyme Activation in Long-Term Blockade of Nitric Oxide Synthesis in Rats

Hypertension

Volumn 34, Issue 4, 1999, Pages 546-551

  Usui, Makoto ^a   Egashira, Kensuke ^a   Kitamoto, Shiro ^a   Koyanagi, Masamichi ^a   Katoh, Makoto ^a   Kataoka, Chu ^a   Shimokawa, Hiroaki ^a   Takeshita, Akira ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Angiotensin converting enzyme; Anions; Nitric oxide; Remodeling; Stress, oxidative

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM; ENZYME ACTIVATION; ENZYME ACTIVITY; HYPERTENSION; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; RAT; SYNTHESIS;

ANIMALS; ANTIOXIDANTS; AORTA; ARGININE; DRUG INTERACTIONS; ENZYME ACTIVATION; ENZYME INHIBITORS; HEMODYNAMIC PROCESSES; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; OXIDATIVE STRESS; PEPTIDYL-DIPEPTIDASE A; RATS; RATS, INBRED WKY; SUPEROXIDES; UP-REGULATION;

EID: 0032749870     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/01.HYP.34.4.546     Document Type: Article

References (40)

1. Harrison DG. Cellular and molecular mechanisms of endothelial cell dysfunction. J Clin Invest. 1997;100:2153-2157.
2. Griendling KK, Alexander RW. Endothelial control of the cardiovascular system: recent advances. FASEB J. 1996;10:283-292.
3. Cooke JP, Dzau VJ. Nitric oxide synthase: role in the genesis of vascular disease. Ann Rev Med. 1997;48:489-509.
4. Egashira K, Inou T, Hirooka Y, Yamada A, Maruoka Y, Kai H, Sugimachi M, Suzuki S, Takeshita A. Impaired coronary blood flow response to acetylcholine in patients with coronary risk factors and proximal atherosclerotic lesions. J Clin Invest. 1993;91:29-37.
5. Egashira K, Inou T, Hirooka Y, Kai H, Sugimachi M, Suzuki S, Kuga T, Urabe Y, Takeshita A. Effects of age on endothelium-dependent vasodilatation of resistance coronary artery by acetylcholine in humans. Circulation. 1993;88:77-81.
6. Egashira K, Suzuki S, Hirooka Y, Kai H, Sugimachi M, Imaizumi T, Takeshita A. Impaired endothelium-dependent vasodilation of large epicardial and resistance coronary arteries in patients with essential hypertension. Hypertension. 1995;25:201-206.
7. Zeiher AM, Drexler H, Saurbier B, Just H. Endothelium-mediated coronary blood flow modulation in humans. J Clin Invest. 1993;92:652-662.
8. Vita JA, Treasure CB, Nabel EG, McLenachan JM, Fish RD, Yeung AC, Vekshtein VI, Selwyn AP, Ganz P. Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease. Circulation. 1990;81:491-497.
9. Ito A, Egashira K, Kadokami T, Fukumoto Y, Takayanagi T, Nakaike R, Kuga T, Sueishi K, Shimokawa H, Takeshita A. Chronic inhibition of endothelium-derived nitric oxide synthesis causes coronary microvascular structural changes and hyperreactivity to serotonin in pigs. Circulation. 1995;92:2636-2644.
10. Takemoto M, Egashira K, Usui M, Numaguchi K, Tomita H, Tsutsui H, Shimokawa H, Sueishi K, Takeshita A. Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rats. J Clin Invest. 1997;99:278-287.
11. Takemoto M, Egashira K, Tomita H, Usui M, Okamoto H, Kitabatake A, Shimokawa H, Sueishi K, Takeshita A. Chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade. Hypertension. 1997;30:1621-1627.
12. Tomita H, Egashira K, Ohara Y, Takemoto M, Koyanagi M, Katoh M, Yamamoto H, Tamaki K, Shimokawa H, Takeshita A. Early induction of transforming growth factor-β via angiotensin II type 1 receptors contributes to cardiac fibrosis induced by long-term blockade of nitric oxide synthesis in rats. Hypertension. 1998;32:273-279.
13. Katoh M, Egashira K, Usui M, Ichiki T, Tomita H, Shimokawa H, Rakugi H, Takeshita A. Cardiac angiotensin II receptor is upregulated by long-term inhibition of nitric oxide synthesis in rats. Circ Res. 1998;83:743-751.
14. G-nitro L-arginine methyl ester due to converting enzyme inhibition. J Cardiovasc Pharmacol. 1996;28:142-148.
15. Rieder M, Carmona R, Krieger J, Pritchard K, Greene AJ. Suppression of angiotensin-converting enzyme expression and activity by shear stress. Circ Res. 1997;80:312-319.
16. Laursen JB, Rajagopalan S, Galis Z, Tarpey M, Freeman BA, Harrison DG. Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension. Circulation. 1997;95:588-593.
17. Suzuki H, Swei A, Zweifach BW, Schmid-Schonbein GW. In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats. Hypertension. 1995;25:1083-1089.
18. Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest. 1993;91:2546-2551.
19. Song K. Shiota N, Takai S, Takashima H, Iwasaki H, Kim S, Miyazaki M. Induction of angiotensin converting enzyme and angiotensin II receptors in the atherosclerotic aorta of high-cholesterol fed Cynomolgus monkeys. Atherosclerosis. 1998;138:171-182.
20. Hoshida S, Nishida M, Yamashita N, Igarashi J, Aoki K, Hori M, Kuzuya T, Tada M. Vascular angiotensin-converting enzyme activity in cholesterol-fed rabbits: effects of enalapril. Atherosclerosis. 1997;130:53-59.
21. Dzan V, Gibbons G, Cooke J, Omoigui N. Vascular biology and medicine in the 1990s: scope, concepts, potentials, and perspectives. Circulation. 1993;87:705-719.
22. Niu XF, Smith CW, Kubes P. Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils. Circ Res. 1994;74:1133-1140.
23. Kurose I, Wolf R, Grisham MB, Aw TY, Specian RD, Granger DN. Microvascular responses to inhibition of nitric oxide production: role of active oxidants. Circ Res. 1995;76:30-39.
24. Takasago T, Peters E, Graham D, Masayasu H, Macrae I. Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion. Br J Pharmacol. 1997;122:1251-1256.
25. Sies H, Masumoto H. Ebsclen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite. Adv Pharmacol. 1997;38:229-246.
26. Cherry PD, Omar HA, Farrell KA, Syuart JS, Wolin MS. Superoxide anion inhibits cGMP-associated bovine pulmonary arterial relaxation. Am J Physiol. 1990;259:H1056-H1062.
27. Rajagopalan S, Kurz S, Munzel T, Tarpey M, Freeman BA, Griendling KK, Harrison DG. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. J Clin Invest. 1996;97:1916-1923.
28. Meier B, Radeke HH, Selle S, Younes M, Sies H, Resch K, Habermehl GG. Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumor necrosis factor-α. Biochem J. 1989;263:539-545.
29. Clozel M, Kuhn H, Heftl F, Baumgatner HR. Endothelial dysfunction and subendothelial monocyte macrophages in hypertension. Hypertension. 1991;18:132-141.
30. Kato H, Hou J, Chobanian AV, Brecher P. Effects of angiotensin II infusion and inhibition of nitric oxide synthase on the rat aorta. Hypertension. 1996;28:153-158.
31. Luvarà G, Pueyo ME, Philippe M, Mandet C, Savoie F, Henrion D, Michel J-B. Chronic blockade of NO synthase activity induces a proinflammatory phenotype in the arterial wall: prevention by angiotensin II antagonism. Arterioscler Thromb Vasc Biol. 1998;18:1408-1416.
32. Lander H. An essential role for free radicals and derived species in signal transduction. FASEB J. 1997;11:118-124.
33. Clancy RM, Leszczynska-Piziak J, Abramson SB. Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J Clin Invest. 1992;90:1116-1121.
34. Hassoun PM, Yu FS, Zulueta JJ, White AC, Lanzillo JJ. Effect of nitric oxide and cell redox status on the regulation of endothelial cell xanthine dehydrogenase. Am J Physiol. 1995;268:L809-L817.
35. Cote CG, Yu F-S, Zulueta JJ, Vosatka RJ, Hassoun PM. Regulation of intracellular xanthine oxidase by endothelial-derived nitric oxide. Am J Physiol. 1996;271:L869-L874.
36. −), superoxide dismutases, and related matters. J Biol Chem. 1997;272:18515-18517.
37. Miller FJ, Gutterman D, Rios C, Heistad D, Davidson B. Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. Circ Res. 1988;82:1298-1305.
38. Fishel RS, Thourai V, Eisenberg SJ, Shai SY, Corson MA, Nabel EG, Bernstein KE, Berk BC. Fibroblast growth factor stimulates angiotensin converting enzyme expression in vascular smooth muscle cells. J Clin Invest. 1995;95:377-387.
39. Kawaguchi H, Sawa H, Yasuda H. Endothelin stimulates angiotensin I to angiotensin II conversion in cultured pulmonary artery endothelial cells. J Mol Cell Cardiol. 1990;22:839-842.
40. Iwai N, Matsunaga M, Kita T, Tei M, Kawai C. Regulation of angiotensin converting enzyme activity in cultured human vascular endothelial cells. Biochem Biophys Res Commun. 1987;149:1179-1185.