Evidence that macrophages in atherosclerotic lesions contain angiotensin II

Circulation

Volumn 98, Issue 8, 1998, Pages 800-807

  Dean Potter, D ^a   Sobey, Christopher G ^a   Tompkins, Pamela K ^a   Rossen, James D ^a   Heistad, Donald D ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Angiotensin; Atherosclerosis; Cells; Immunohistochemistry

Indexed keywords

ANGIOTENSIN; CHOLESTEROL; POLYCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; ARTERY INTIMA; ARTERY MEDIA; ARTICLE; ATHERECTOMY; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY CIRCUMFLEX BRANCH; ENDOTHELIUM CELL; HUMAN; HUMAN TISSUE; MACROPHAGE; MONKEY; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; THORACIC AORTA;

EID: 0344015781     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.cir.98.8.800     Document Type: Article

References (31)

1. Ross R. The pathogenesis of atherosclerosis: an update. N Engl J Med. 1986;314:488-500.
2. Gomez RA, Norling LL, Wilfong N, Isakson P, Lynch KR, Hock R, Quesenberry P. Leukocytes synthesize angiotensinogen. Hypertension. 1993;21:470-475.
3. Hinman L, Stevens C, Matthay R, Bernhard J, Gee J. Angiotensin convertase activities in human alveolar macrophages: effects of cigarette smoking and sarcoidosis. Science. 1979;205:202-203.
4. Kitazono T, Padgett RC, Armstrong ML, Tompkins PK, Heistad DD. Evidence that angiotensin II is present in human monocytes. Circulation. 1995;91:1129-1134.
5. Chobanian AV, Haudenschild CC, Nickerson C, Drago R. Anti-atherogenic effect of captopril in the Watanabe heritable hyperlipidemic rabbit. Hypertension. 1990;15:327-331.
6. Keidar S, Kaplan M, Aviram M Angiotensin II-modified LDL is taken up by macrophages via the scavenger receptor, leading to cellular cholesterol accumulation. Arterioscler Thromb Vasc Biol. 1996;16:97-105.
7. Armstrong ML, Warner ED, Conner WE. Regression of coronary atheromatosis in rhesus monkeys. Circ Res. 1970;27:59-67.
8. Armstrong ML, Heistad DD, Marcus ML, Piegors DJ, Abboud FM. Hemodynamic sequelae of regression of experimental atherosclerosis. J Clin Invest. 1983;71:104-113.
9. Padgett RC, Heistad DD, Mügge A, Armstrong ML, Piegors DJ, Lopez JAG. Vascular responses to activated leukocytes after regression of atherosclerosis. Circ Res. 1992;70:423-429.
10. Fuxe K, Ganten D, Hökfelt T, Bolme P. Immunohistochemical evidence for the existence of angiotensin II-containing nerve terminals in the brain and spinal cord of the rat. Neurosci Lett. 1976;2:229-234.
11. Ganong WF. Origin of the angiotensin II secreted by cells. Soc Exp Biol Med. 1994;205:213-219.
12. Hunt MK, Ramos SP, Geary KM, Norling LL, Peach MJ, Gomez RA, Carey RM. Colocalization and release of angiotensin and renin in renal cortical cells. Am J Physiol. 1992;263(3 Pt 2):F363-F373.
13. Swaab DF, Poole CW. Specificity of oxytocin and vasopressin immunofluorescence. J Endocrinol. 1975;66:263-272.
14. Imboden H, Harding JW, Abhold RH, Ganten D, Felix D. Improved immunohistochemical staining of angiotensin II in rat brain using affinity purified antibodies. Brain Res. 1987;426:225-234.
15. Gown AM, Tsukada T, Ross R. Immunocytochemical analysis of the cellular composition of human atherosclerotic lesions. Am J Pathol. 1986;125:191-207.
16. Kargi HA, Campbell FJ, Kuhn C. Elastase and cathepsin G of human monocytes: heterogeneity and subcellular localization of peroxidase-positive granules. J Histochem Cytochem. 1990;38:1179-1186.
17. Senior RM, Campbell EJ. Cathepsin G in human mononuclear phagocytes: comparisons between monocytes and U937 monocyte-like cells. J Immunol. 1984;132:2547-2551.
18. Wintroub BU, Klickstein LB, Dzau VJ, Watt WK. Granulocyte-angiotensin system: identification of angiotensinogen as the plasma protein substrate of leukocyte cathepsin G. Biochemistry. 1984;23:227-232.
19. Weinstock JV, Blum AM. Synthesis of angiotensins by cultured granuloma macrophages in murine Schistosomiasis mansoni. Cell Immunol. 1987;107:273-280.
20. Ehlers MR, Riordan JF. Angiotensin-converting enzyme: new concepts concerning its biological role. Biochemistry. 1989;28:5311-5318.
21. Falkenhahn M, Franke F, Bohle RM, Zhu YC, Stauss HM, Bachmann S, Danilov S, Unger T. Cellular distribution of angiotensin-converting enzyme after myocardial infarction. Hypertension. 1995;25:219-226.
22. Simon MR, Kamlay MT, Khan M, Melmon K. Angiotensin II binding to human mononuclear cells. Immunopharmacol Immunotoxicol. 1989;11: 63-80.
23. Thomas DW, Hoffman MD. Identification of macrophage receptors for angiotensin: a potential role in antigen uptake for T lymphocyte response? J Immunol. 1984;132:2807-2812.
24. Dostal DE, Rothblum KN, Conrad KM, Cooper GR, Baker KM. Detection of angiotensin I and II in cultured rat cardiac myocytes and fibroblasts. Am J Physiol. 1992;263:C851-C863.
25. Kifor I, Dzau VJ. Endothelial renin-angiotensin pathway: evidence for intracellular synthesis and secretion of angiotensins. Circ Res. 1987;60: 422-428.
26. Naftilan AJ, Pratt RE, Dzau VJ. Induction of platelet-derived growth factor A-chain and c-myc gene expression by angiotensin II in cultured rat vascular smooth muscle cells. J Clin Invest. 1989;83:1419-1424.
27. Metsarinne K, Stoll M, Gohlke P, Paul M, Unger T. Angiotensin II is antiproliferative for coronary endothelial cells in vitro. Pharm Pharmacol Lett. 1992;2:150-152.
28. Itoh H, Mukoyama M, Pratt RE, Gibbons GH, Dzau VJ. Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II. J Clin Invest. 1993;91:2268-2274.
29. Dezso B, Foris G. Effect of angiotensin II on the Fc receptor activity of rat macrophages. Immunology. 1981;42:277-283.
30. Foris G, Dezso B, Medgyesi GA, Fust G. Effect of angiotensin II on macrophage functions. Immunology. 1983;48:529-535.
31. Goetzl EJ, Klickstein LB, Watt KWK, Wintroub BU. The preferential human mononuclear leukocyte chemotactic activity of the substituent tetrapeptides of angiotensin II. Biochem Biophys Res Commun. 1980;97: 1097-1102.