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Volumn 5, Issue 5, 1999, Pages 1231-1240

Loss of heterozygosity of the Rb gene correlates with pRb protein expression and associates with p53 alteration in human esophageal cancer

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; RETINOBLASTOMA PROTEIN;

EID: 0032957746     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (75)

References (50)
  • 2
    • 0028171292 scopus 로고
    • 1 phase progression: Cycling on cue
    • 1 phase progression: cycling on cue. Cell, 79: 551-555, 1994.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 3
    • 0025905183 scopus 로고
    • The E2F transcription factor is a cellular target for the RB protein
    • Chellappan, S. P., Hiebert, S., Mudryj, M., Horowitz, J. M., and Nevins, J. R. The E2F transcription factor is a cellular target for the RB protein. Cell, 65: 1053-1061, 1991.
    • (1991) Cell , vol.65 , pp. 1053-1061
    • Chellappan, S.P.1    Hiebert, S.2    Mudryj, M.3    Horowitz, J.M.4    Nevins, J.R.5
  • 4
    • 0024439444 scopus 로고
    • The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
    • Buchkovich, K., Duffy, L. A., and Harlow, E. The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell, 58: 1097-1105, 1989.
    • (1989) Cell , vol.58 , pp. 1097-1105
    • Buchkovich, K.1    Duffy, L.A.2    Harlow, E.3
  • 5
    • 0027491775 scopus 로고
    • Expression of transcription factor E2F1 induces quiescent cells to enter S phase
    • Johnson, D. G., Schwarz, J. K., Cress, W. D., and Nevins, J. R. Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature (Lond.), 365: 349-352, 1993.
    • (1993) Nature (Lond.) , vol.365 , pp. 349-352
    • Johnson, D.G.1    Schwarz, J.K.2    Cress, W.D.3    Nevins, J.R.4
  • 6
    • 0025323366 scopus 로고
    • Role of the retinoblastoma gene in the initiation and progression of human cancer
    • Benedict, W. F., Xu, H. J., Hu, S. X., and Takahashi, R. Role of the retinoblastoma gene in the initiation and progression of human cancer. J. Clin. Invest., 85: 988-993, 1990.
    • (1990) J. Clin. Invest. , vol.85 , pp. 988-993
    • Benedict, W.F.1    Xu, H.J.2    Hu, S.X.3    Takahashi, R.4
  • 7
    • 0025615654 scopus 로고
    • The retinoblastoma gene: Its role in human malignancies
    • Benedict, W. F., Xu, H. J., and Takahashi, R. The retinoblastoma gene: its role in human malignancies. Cancer Invest., 8: 535-540, 1990.
    • (1990) Cancer Invest. , vol.8 , pp. 535-540
    • Benedict, W.F.1    Xu, H.J.2    Takahashi, R.3
  • 8
    • 0017724098 scopus 로고
    • Mutation and cancer in man
    • Knudson, A. G. Mutation and cancer in man. Cancer (Phila.), 39: 1882-1886, 1977.
    • (1977) Cancer (Phila.) , vol.39 , pp. 1882-1886
    • Knudson, A.G.1
  • 9
    • 0027516618 scopus 로고
    • Loss of RB protein expression in primary bladder cancer correlates with loss of heterozygosity at the RB locus and tumor progression
    • Xu, H. J., Cairns, P., Hu, S. X., Knowles, M. A., and Benedict, W. F. Loss of RB protein expression in primary bladder cancer correlates with loss of heterozygosity at the RB locus and tumor progression. Int. J. Cancer, 53: 781-784, 1993.
    • (1993) Int. J. Cancer , vol.53 , pp. 781-784
    • Xu, H.J.1    Cairns, P.2    Hu, S.X.3    Knowles, M.A.4    Benedict, W.F.5
  • 10
    • 0027956684 scopus 로고
    • Loss of heterozygosity at the RB locus correlates with loss of RB protein in primary malignant neuroendocrine lung carcinomas
    • Gouyer, V., Gazzeri, S., Brambilla, E., Bolon, I., Moro, D., Perron, P., Benabid, A. L., and Brambilla, C. Loss of heterozygosity at the RB locus correlates with loss of RB protein in primary malignant neuroendocrine lung carcinomas. Int. J. Cancer, 58: 818-824, 1994.
    • (1994) Int. J. Cancer , vol.58 , pp. 818-824
    • Gouyer, V.1    Gazzeri, S.2    Brambilla, E.3    Bolon, I.4    Moro, D.5    Perron, P.6    Benabid, A.L.7    Brambilla, C.8
  • 12
    • 0026729463 scopus 로고
    • The retinoblastoma gene in breast cancer: Allele loss is not correlated with loss of gene protein expression
    • Borg, A., Zhang, Q. X., Alm, P., Olsson, H., and Sellberg, G. The retinoblastoma gene in breast cancer: allele loss is not correlated with loss of gene protein expression. Cancer Res., 52: 2991-2994, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 2991-2994
    • Borg, A.1    Zhang, Q.X.2    Alm, P.3    Olsson, H.4    Sellberg, G.5
  • 13
    • 0028017632 scopus 로고
    • Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma
    • Yoo, G. H., Xu, H-J., Brennan, J. A., Westra, W., Hruban, R. H., Koch, W., Benedict, W. F., and Sidransky, D. Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma. Cancer Res., 54: 4603-4606, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4603-4606
    • Yoo, G.H.1    Xu, H.-J.2    Brennan, J.A.3    Westra, W.4    Hruban, R.H.5    Koch, W.6    Benedict, W.F.7    Sidransky, D.8
  • 14
    • 0028961786 scopus 로고
    • Frequent loss of heterozygosity at the retinoblastoma susceptibility gene (RB) locus in aggressive pituitary tumors: Evidence for a chromosome 13 tumor suppressor gene other than RB
    • Pei, L., Melmed, S., Scheithauer, B., Kovacs, K., Benedict, W. F., and Prager, D. Frequent loss of heterozygosity at the retinoblastoma susceptibility gene (RB) locus in aggressive pituitary tumors: evidence for a chromosome 13 tumor suppressor gene other than RB. Cancer Res., 55: 1613-1616, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 1613-1616
    • Pei, L.1    Melmed, S.2    Scheithauer, B.3    Kovacs, K.4    Benedict, W.F.5    Prager, D.6
  • 15
    • 0029040630 scopus 로고
    • Loss of heterozygosity of tumor suppressor genes in testis cancer
    • Peng, H. Q., Bailey, D., Bronson, D., Goss, P. E., and Hogg, D. Loss of heterozygosity of tumor suppressor genes in testis cancer. Cancer Res., 55: 2871-2875, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 2871-2875
    • Peng, H.Q.1    Bailey, D.2    Bronson, D.3    Goss, P.E.4    Hogg, D.5
  • 18
    • 0028023861 scopus 로고
    • Deletions of chromosome 13q, mutations in Retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma
    • Zhang, X., Xu, H. J., Murakarni, Y., Sachse, R., Yashima, K., Hirohashi, S., Hu, S. X., Benedict, W. F., and Sekiya, T. Deletions of chromosome 13q, mutations in Retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma. Cancer Res., 54: 4177-4182, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4177-4182
    • Zhang, X.1    Xu, H.J.2    Murakarni, Y.3    Sachse, R.4    Yashima, K.5    Hirohashi, S.6    Hu, S.X.7    Benedict, W.F.8    Sekiya, T.9
  • 21
    • 0030989021 scopus 로고    scopus 로고
    • Altered retinoblastoma protein expression in nonsmall cell lung cancer: Its synergistic effects with altered ras and p53 protein status on prognosis
    • Dosaka-Akita, H., Hu, S. X., Fujino, M., Harada, M., Kinoshita, I., Xu, H. J., Kuzumaki, N., Kawakami, Y., and Benedict, W. F. Altered retinoblastoma protein expression in nonsmall cell lung cancer: its synergistic effects with altered ras and p53 protein status on prognosis. Cancer (Phila.), 79: 1329-1337, 1997.
    • (1997) Cancer (Phila.) , vol.79 , pp. 1329-1337
    • Dosaka-Akita, H.1    Hu, S.X.2    Fujino, M.3    Harada, M.4    Kinoshita, I.5    Xu, H.J.6    Kuzumaki, N.7    Kawakami, Y.8    Benedict, W.F.9
  • 22
    • 0030795974 scopus 로고    scopus 로고
    • Combined and sequential expression of p53, Rb, Ras and Bcl-2 in bronchial preneoplastic lesions
    • Ferron, P. E., Bagni, I., Guidoboni, M., Beccati, M. D., and Nenci, I. Combined and sequential expression of p53, Rb, Ras and Bcl-2 in bronchial preneoplastic lesions. Tumori, 83: 587-593, 1997.
    • (1997) Tumori , vol.83 , pp. 587-593
    • Ferron, P.E.1    Bagni, I.2    Guidoboni, M.3    Beccati, M.D.4    Nenci, I.5
  • 23
    • 0029854227 scopus 로고    scopus 로고
    • The loss of heterozygosity in retinoblastoma and p53 suppressor genes as a prognostic indicator for head and neck cancer
    • Gleich, L. L., Li, Y. Q., Biddinger, P. W., Gartside, P. S., Stambrook, P. J., Pavelic, Z. P., and Gluckman, J. L. The loss of heterozygosity in retinoblastoma and p53 suppressor genes as a prognostic indicator for head and neck cancer. Laryngoscope, 706: 1378-1381, 1996.
    • (1996) Laryngoscope , vol.706 , pp. 1378-1381
    • Gleich, L.L.1    Li, Y.Q.2    Biddinger, P.W.3    Gartside, P.S.4    Stambrook, P.J.5    Pavelic, Z.P.6    Gluckman, J.L.7
  • 24
    • 0026041836 scopus 로고
    • Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas
    • Murakami, Y., Hayashi, K., Hirohashi, S., and Sekiya, T. Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas. Cancer Res., 51: 5520-5525, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 5520-5525
    • Murakami, Y.1    Hayashi, K.2    Hirohashi, S.3    Sekiya, T.4
  • 25
    • 0028972262 scopus 로고
    • Abnormalities of p53 and p110RB tumor suppressor gene expression in human soft tissue tumors: Correlations with cell proliferation and tumor grade
    • Wang, J., Coltrera, M. D., and Gown, A. M. Abnormalities of p53 and p110RB tumor suppressor gene expression in human soft tissue tumors: correlations with cell proliferation and tumor grade. Mod. Pathol., 8: 837-842, 1995.
    • (1995) Mod. Pathol. , vol.8 , pp. 837-842
    • Wang, J.1    Coltrera, M.D.2    Gown, A.M.3
  • 26
  • 31
    • 0030254295 scopus 로고    scopus 로고
    • p53-mediated apoptosis: Mechanisms and regulation
    • Haupt, Y., and Oren, M. p53-mediated apoptosis: mechanisms and regulation. Behring Inst. Mitt., 97: 32-59, 1996.
    • (1996) Behring Inst. Mitt. , vol.97 , pp. 32-59
    • Haupt, Y.1    Oren, M.2
  • 32
    • 0029910628 scopus 로고    scopus 로고
    • Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system
    • Macleod, K. F., Hu, Y., and Jacks, T. Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J., 75: 6178-6188, 1996.
    • (1996) EMBO J , vol.75 , pp. 6178-6188
    • Macleod, K.F.1    Hu, Y.2    Jacks, T.3
  • 33
    • 0025583115 scopus 로고
    • The nuclear oncoproteins: RB and p53
    • Cowell, J. K. The nuclear oncoproteins: RB and p53. Semin. Cancer Biol., 1: 437-446, 1990.
    • (1990) Semin. Cancer Biol. , vol.1 , pp. 437-446
    • Cowell, J.K.1
  • 34
    • 0024894289 scopus 로고
    • The p53 tumor suppressor gene and gene product
    • Levine, A. J. The p53 tumor suppressor gene and gene product. Princess Takamatsu, 20: 221-230, 1989.
    • (1989) Princess Takamatsu , vol.20 , pp. 221-230
    • Levine, A.J.1
  • 35
    • 0025953696 scopus 로고
    • The states of the p53 and retinoblastoma genes in human cervical carcinoma cell lines
    • Scheffner, M., Munder, K., Byrne, J. C., and Howley, P. M. The states of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc. Natl. Acad. Sci. USA, 88: 5523-5527, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5523-5527
    • Scheffner, M.1    Munder, K.2    Byrne, J.C.3    Howley, P.M.4
  • 37
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr, C. J. Cancer cell cycles. Science (Washington DC), 274: 1672-1677, 1996.
    • (1996) Science (Washington DC) , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 38
    • 0028168391 scopus 로고
    • p53 tumor suppressor gene mutation in early esophageal precancerous lesions and carcinoma among high-risk populations in Henan, China
    • Gao, H., Wang, L. D., Zhou, Q., Hong, J-Y., Huang, T-Y., and Yang, C. S. p53 tumor suppressor gene mutation in early esophageal precancerous lesions and carcinoma among high-risk populations in Henan, China. Cancer Res., 54: 4342-4346, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4342-4346
    • Gao, H.1    Wang, L.D.2    Zhou, Q.3    Hong, J.-Y.4    Huang, T.-Y.5    Yang, C.S.6
  • 39
    • 0033033245 scopus 로고    scopus 로고
    • Role of p53 gene mutation in human esophageal carcinogenesis: Results from immunohistochemical and mutation analysis of carcinomas and nearby non-cancerous lesions
    • in press
    • Shi, T., Yang, G-Y, Wang, L. D. Z., Xue, Z., Feng, B., Ding, W., Xing, E. P., and Yang, C. S. Role of p53 gene mutation in human esophageal carcinogenesis: results from immunohistochemical and mutation analysis of carcinomas and nearby non-cancerous lesions. Carcinogenesis (Lond.), in press, 1999.
    • (1999) Carcinogenesis (Lond.)
    • Shi, T.1    Yang, G.-Y.2    Wang, L.D.Z.3    Xue, Z.4    Feng, B.5    Ding, W.6    Xing, E.P.7    Yang, C.S.8
  • 40
    • 0030610256 scopus 로고    scopus 로고
    • Immunohistochemical studies of Waf1p21, p16, pRb, and p53 in human esophageal carcinoma and neighboring epithelia from a high-risk area in northern China
    • Yang, G-Y., Zhang, Z., Jie, L., Seril, D., Wang, L. D., Goldstein, S., and Yang, C. S. Immunohistochemical studies of Waf1p21, p16, pRb, and p53 in human esophageal carcinoma and neighboring epithelia from a high-risk area in northern China. Int. J. Cancer, 72: 746-751, 1997.
    • (1997) Int. J. Cancer , vol.72 , pp. 746-751
    • Yang, G.-Y.1    Zhang, Z.2    Jie, L.3    Seril, D.4    Wang, L.D.5    Goldstein, S.6    Yang, C.S.7
  • 41
    • 0028075502 scopus 로고
    • Changes in p53 and cyclin D1 protein levels and cell proliferation in different stages of human esophageal and gastric-cardia carcinogenesis
    • Wang, L. D., Shi, S. T., Zhou, Q., Goldstein, S., Hong, J. Y., Shao, P., Qiu, S. L., and Yang, C. S. Changes in p53 and cyclin D1 protein levels and cell proliferation in different stages of human esophageal and gastric-cardia carcinogenesis. Int. J. Cancer, 59: 514-519, 1994.
    • (1994) Int. J. Cancer , vol.59 , pp. 514-519
    • Wang, L.D.1    Shi, S.T.2    Zhou, Q.3    Goldstein, S.4    Hong, J.Y.5    Shao, P.6    Qiu, S.L.7    Yang, C.S.8
  • 47
    • 0030332113 scopus 로고    scopus 로고
    • The molecular biology of esophageal carcinoma
    • Meltzer, S. J. The molecular biology of esophageal carcinoma. Rec. Results Cancer Res., 142: 1-8, 1996.
    • (1996) Rec. Results Cancer Res. , vol.142 , pp. 1-8
    • Meltzer, S.J.1
  • 50
    • 0032161624 scopus 로고    scopus 로고
    • p63, a p53 homolog at 3p27, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang, A., Kaghad, M., Wang, Y., Gillett, E., Fleming, M. D., Dotsch, V., Andrews, N. C., Caput, D., and McKeon, F. p63, a p53 homolog at 3p27, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol. Cell, 2: 305-316, 1998.
    • (1998) Mol. Cell , vol.2 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5    Dotsch, V.6    Andrews, N.C.7    Caput, D.8    McKeon, F.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.