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Volumn 95, Issue 10, 2002, Pages 1188-1194

Thiazolidinediones: A review of their benefits and risks

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; PIOGLITAZONE; ROSIGLITAZONE; TROGLITAZONE;

EID: 0036774734     PISSN: 00384348     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007611-200295100-00017     Document Type: Review
Times cited : (23)

References (85)
  • 1
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 329:977-986
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 2
    • 0029147687 scopus 로고
    • Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: A randomized prospective 6-year study
    • Ohkubo Y, Kishikawa H, Araki E, et al: Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: A randomized prospective 6-year study. Diabetes Res Clin Pract 1995; 28:103-117
    • (1995) Diabetes Res Clin Pract , vol.28 , pp. 103-117
    • Ohkubo, Y.1    Kishikawa, H.2    Araki, E.3
  • 3
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study Group: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352:837-853
    • (1998) Lancet , vol.352 , pp. 837-853
  • 4
    • 0018341014 scopus 로고
    • Diabetes and cardiovascular disease risk factors: The Framingham Study
    • Kannel WB, McGee DL: Diabetes and cardiovascular disease risk factors: The Framingham Study. Circulation 1979; 59:8-13
    • (1979) Circulation , vol.59 , pp. 8-13
    • Kannel, W.B.1    McGee, D.L.2
  • 6
    • 0034656345 scopus 로고    scopus 로고
    • Vascular complications of diabetes
    • Donnelly R, Emslie-Smith AM, Gardner ID, et al: Vascular complications of diabetes. BMJ 2000; 320:1062-1066
    • (2000) BMJ , vol.320 , pp. 1062-1066
    • Donnelly, R.1    Emslie-Smith, A.M.2    Gardner, I.D.3
  • 7
    • 0032727659 scopus 로고    scopus 로고
    • Thiazolidinediones: A new class of antidiabetic drugs
    • Day C: Thiazolidinediones: A new class of antidiabetic drugs. Diabet Med 1999; 16:179-192
    • (1999) Diabet Med , vol.16 , pp. 179-192
    • Day, C.1
  • 8
    • 0034681773 scopus 로고    scopus 로고
    • Thiazolidinediones: An update
    • Schoonjans K, Auwerx J: Thiazolidinediones: An update. Lancet 2000; 355:1008-1010
    • (2000) Lancet , vol.355 , pp. 1008-1010
    • Schoonjans, K.1    Auwerx, J.2
  • 9
    • 0033578476 scopus 로고    scopus 로고
    • Pharmacologic therapy for type 2 diabetes mellitus
    • DeFronzo R: Pharmacologic therapy for type 2 diabetes mellitus. Ann Intern Med 1999; 131:281-303
    • (1999) Ann Intern Med , vol.131 , pp. 281-303
    • DeFronzo, R.1
  • 10
    • 0034604234 scopus 로고    scopus 로고
    • Pharmacologic therapy for type 2 diabetes mellitus
    • Defronzo R: Pharmacologic therapy for type 2 diabetes mellitus (Letter). Ann Intern Med 2000; 133:73-74
    • (2000) Ann Intern Med , vol.133 , pp. 73-74
    • Defronzo, R.1
  • 11
    • 0029999139 scopus 로고    scopus 로고
    • Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients
    • Kumar S, Boulton AJM, Beck-Nielsen H, et al: Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients. Diabetologia 1996; 39:701-709
    • (1996) Diabetologia , vol.39 , pp. 701-709
    • Kumar, S.1    Boulton, A.J.M.2    Beck-Nielsen, H.3
  • 12
    • 0032005178 scopus 로고    scopus 로고
    • Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus
    • Maggs DG, Buchanan TA, Burant CF, et al: Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. Ann Intern Med 1998; 128:176-185
    • (1998) Ann Intern Med , vol.128 , pp. 176-185
    • Maggs, D.G.1    Buchanan, T.A.2    Burant, C.F.3
  • 13
    • 0032568257 scopus 로고    scopus 로고
    • Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus
    • Inzucchi SE, Maggs DG, Spollett GR, et al: Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus. N Engl J Med 1998; 338:867-872
    • (1998) N Engl J Med , vol.338 , pp. 867-872
    • Inzucchi, S.E.1    Maggs, D.G.2    Spollett, G.R.3
  • 14
    • 0031736142 scopus 로고    scopus 로고
    • Troglitazone decreases the proportion of small, dense LDL and increases the resistance of LDL to oxidation in obese subjects
    • Tack CJ, Smits P, Demacker PNM, et al: Troglitazone decreases the proportion of small, dense LDL and increases the resistance of LDL to oxidation in obese subjects. Diabetes Care 1998; 21:796-799
    • (1998) Diabetes Care , vol.21 , pp. 796-799
    • Tack, C.J.1    Smits, P.2    Demacker, P.N.M.3
  • 15
    • 0032960540 scopus 로고    scopus 로고
    • Troglitazone directly increases HDL cholesterol levels
    • Nozue T, Michishita I, Minagawa F, et al: Troglitazone directly increases HDL cholesterol levels. Diabetes Care 1999; 22:355-356
    • (1999) Diabetes Care , vol.22 , pp. 355-356
    • Nozue, T.1    Michishita, I.2    Minagawa, F.3
  • 16
    • 0001123254 scopus 로고    scopus 로고
    • The effect of thiazolidinediones on HDL subfractions
    • Ovalle F, Bell DSH: The effect of thiazolidinediones on HDL subfractions. Diabetes 2000; 49(suppl 1):A269
    • (2000) Diabetes , vol.49 , Issue.SUPPL. 1
    • Ovalle, F.1    Bell, D.S.H.2
  • 17
    • 0345465917 scopus 로고    scopus 로고
    • Troglitazone: Antihyperglycemic activity and potential role in the treatment of type 2 diabetes
    • Scheen AJ, Lefébvre PJ: Troglitazone: Antihyperglycemic activity and potential role in the treatment of type 2 diabetes. Diabetes Care 1999; 22:1568-1577
    • (1999) Diabetes Care , vol.22 , pp. 1568-1577
    • Scheen, A.J.1    Lefébvre, P.J.2
  • 18
    • 0033039662 scopus 로고    scopus 로고
    • Mechanisms by which thiazolidinediones enhance insulin action
    • Reginato MJ, Lazar MA: Mechanisms by which thiazolidinediones enhance insulin action. Trends Endocrinol Metab 1999; 10:9-13
    • (1999) Trends Endocrinol Metab , vol.10 , pp. 9-13
    • Reginato, M.J.1    Lazar, M.A.2
  • 19
    • 0028901028 scopus 로고
    • Enhancement of insulin sensitivity by troglitazone lowers blood pressure in diabetic hypertensives
    • Ogihara T, Rakugi H, Ikegami H, et al: Enhancement of insulin sensitivity by troglitazone lowers blood pressure in diabetic hypertensives. Am J Hypertens 1995; 8:316-320
    • (1995) Am J Hypertens , vol.8 , pp. 316-320
    • Ogihara, T.1    Rakugi, H.2    Ikegami, H.3
  • 20
    • 0031054699 scopus 로고    scopus 로고
    • Cardiac and glycemic benefits of troglitazone treatment in NIDDM
    • The Troglitazone Study Group
    • Ghazzi MN, Perez JE, Antonucci TK, et al: Cardiac and glycemic benefits of troglitazone treatment in NIDDM. The Troglitazone Study Group. Diabetes 1997; 46:433-439
    • (1997) Diabetes , vol.46 , pp. 433-439
    • Ghazzi, M.N.1    Perez, J.E.2    Antonucci, T.K.3
  • 21
    • 0344780882 scopus 로고    scopus 로고
    • Vasodilatory effects of troglitazone improve blood pressure at rest and during mental stress in type 2 diabetes mellitus
    • Sung BH, Izzo JL, Dandona P, et al: Vasodilatory effects of troglitazone improve blood pressure at rest and during mental stress in type 2 diabetes mellitus. Hypertension 1999; 34:83-88
    • (1999) Hypertension , vol.34 , pp. 83-88
    • Sung, B.H.1    Izzo, J.L.2    Dandona, P.3
  • 22
    • 0030033508 scopus 로고    scopus 로고
    • Effects of troglitazone, a new hypoglycemic agent in patients with NIDDM poorly controlled by diet therapy
    • Iwamoto Y, Kosaka K, Kuzuya T, et al: Effects of troglitazone, a new hypoglycemic agent in patients with NIDDM poorly controlled by diet therapy. Diabetes Care 1996; 19:151-156
    • (1996) Diabetes Care , vol.19 , pp. 151-156
    • Iwamoto, Y.1    Kosaka, K.2    Kuzuya, T.3
  • 23
    • 0002427014 scopus 로고    scopus 로고
    • Rosiglitazone improves blood pressure in patients with type 2 diabetes mellitus
    • Bakris GL, Dole JF, Porter LE, et al: Rosiglitazone improves blood pressure in patients with type 2 diabetes mellitus. Diabetes 2000; 49 (suppl 1):A96
    • (2000) Diabetes , vol.49 , Issue.SUPPL. 1
    • Bakris, G.L.1    Dole, J.F.2    Porter, L.E.3
  • 24
    • 0030868981 scopus 로고    scopus 로고
    • Effects of troglitazone on insulin action and cardiovascular risk factors in patients with non-insulin-dependent diabetes
    • Sironi AM, Vichi S, Gastaldelli A, et al: Effects of troglitazone on insulin action and cardiovascular risk factors in patients with non-insulin-dependent diabetes. Clin Pharmacol Ther 1997; 62:194-202
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 194-202
    • Sironi, A.M.1    Vichi, S.2    Gastaldelli, A.3
  • 25
    • 0002434196 scopus 로고    scopus 로고
    • Troglitazone improves cardiovascular risk profile compared with glibencamide
    • Claudi T, Starkie M, Frith L, et al: Troglitazone improves cardiovascular risk profile compared with glibencamide. Diabet Med 1997; 14(suppl 4):530
    • (1997) Diabet Med , vol.14 , Issue.SUPPL. 4 , pp. 530
    • Claudi, T.1    Starkie, M.2    Frith, L.3
  • 26
    • 0031768586 scopus 로고    scopus 로고
    • Effect of troglitazone on microalbuminuria in patients with incipient diabetic nephropathy
    • Imano E, Kanda T, Nakatani Y, et al: Effect of troglitazone on microalbuminuria in patients with incipient diabetic nephropathy. Diabetes Care 1998; 21:2135-2139
    • (1998) Diabetes Care , vol.21 , pp. 2135-2139
    • Imano, E.1    Kanda, T.2    Nakatani, Y.3
  • 27
    • 0005217321 scopus 로고    scopus 로고
    • Troglitazone improves diabetic nephropathy in patients with type 2 diabetes
    • Miura Y, Kato Y, Yamamoto N, et al: Troglitazone improves diabetic nephropathy in patients with type 2 diabetes. Diabetes, 2000; 49(suppl 1):A19-A20
    • (2000) Diabetes , vol.49 , Issue.SUPPL. 1
    • Miura, Y.1    Kato, Y.2    Yamamoto, N.3
  • 28
    • 0002553904 scopus 로고    scopus 로고
    • Rosiglitazone produces long-term reductions in urinary albumin excretion in type 2 diabetes
    • Bakris G, Weston WM, Rappaport EB, et al: Rosiglitazone produces long-term reductions in urinary albumin excretion in type 2 diabetes. Diabetologia 1999; 42 (suppl 1):A230
    • (1999) Diabetologia , vol.42 , Issue.SUPPL. 1
    • Bakris, G.1    Weston, W.M.2    Rappaport, E.B.3
  • 29
    • 0002553906 scopus 로고    scopus 로고
    • Rosiglitazone reduces urinary albumin excretion in type 2 diabetes
    • Freed MI, Weston WM, Viberti G: Rosiglitazone reduces urinary albumin excretion in type 2 diabetes. Diabetologia 1999; 42(suppl 1):A230
    • (1999) Diabetologia , vol.42 , Issue.SUPPL. 1
    • Freed, M.I.1    Weston, W.M.2    Viberti, G.3
  • 30
    • 0031724132 scopus 로고    scopus 로고
    • Potent inhibitory effect of troglitazone on carotid arterial wall thickness in type 2 diabetes
    • Minamikawa J, Tanaka S, Yamauchi M, et al: Potent inhibitory effect of troglitazone on carotid arterial wall thickness in type 2 diabetes. J Clin Endocrinol Metab 1998; 83:1818-1820
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1818-1820
    • Minamikawa, J.1    Tanaka, S.2    Yamauchi, M.3
  • 31
    • 0002025823 scopus 로고    scopus 로고
    • Troglitazone reduces intimal hyperplasia after coronary stent implantation in patients with type 2 diabetes mellitus: A serial intravascular ultrasound study
    • Tagaki T, Yoshida JK, Akasaka T, et al: Troglitazone reduces intimal hyperplasia after coronary stent implantation in patients with type 2 diabetes mellitus: A serial intravascular ultrasound study (Abstract 886-2). J Am Coll Cardiol 1999; 33:100A
    • (1999) J Am Coll Cardiol , vol.33
    • Tagaki, T.1    Yoshida, J.K.2    Akasaka, T.3
  • 32
    • 0032167679 scopus 로고    scopus 로고
    • Troglitazone, an insulin sensitizer, increases forearm blood flow in humans
    • Fujishima S, Ohya Y, Nakamura Y, et al: Troglitazone, an insulin sensitizer, increases forearm blood flow in humans. Am J Hypertens 1998; 11:1134-1137
    • (1998) Am J Hypertens , vol.11 , pp. 1134-1137
    • Fujishima, S.1    Ohya, Y.2    Nakamura, Y.3
  • 33
    • 0031977203 scopus 로고    scopus 로고
    • Insulin induced vasodilatation and endothelial function in obesity/insulin resistance, effects of troglitazone
    • Tack CJJ, Ong MKE, Lutterman JA, et al: Insulin induced vasodilatation and endothelial function in obesity/insulin resistance, effects of troglitazone. Diabetologia 1998; 41:569-576
    • (1998) Diabetologia , vol.41 , pp. 569-576
    • Tack, C.J.J.1    Ong, M.K.E.2    Lutterman, J.A.3
  • 34
    • 0031695538 scopus 로고    scopus 로고
    • Effects of troglitazone on coagulation-fibrinolysis abnormalities in patients with type II diabetes mellitus
    • Kubo K: Effects of troglitazone on coagulation-fibrinolysis abnormalities in patients with type II diabetes mellitus. Curr Ther Res Clin Exp 1998; 59:537-544
    • (1998) Curr Ther Res Clin Exp , vol.59 , pp. 537-544
    • Kubo, K.1
  • 35
    • 0031802033 scopus 로고    scopus 로고
    • Effect of troglitazone on fibrinolysis and activated coagulation in patients with non-insulin-dependent diabetes mellitus
    • Fonseca VA, Reynolds T, Hemphill D, et al: Effect of troglitazone on fibrinolysis and activated coagulation in patients with non-insulin-dependent diabetes mellitus. J Diabetes Comp 1998; 4:181-186
    • (1998) J Diabetes Comp , vol.4 , pp. 181-186
    • Fonseca, V.A.1    Reynolds, T.2    Hemphill, D.3
  • 36
    • 0030855145 scopus 로고    scopus 로고
    • Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis and fibrinolysis in women with polycystic ovary syndrome
    • Ehrmann DA, Schneider DJ, Sobel BE, et al: Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis and fibrinolysis in women with polycystic ovary syndrome. J Clin Endocrinol Metab 1997; 82:2108-2116
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2108-2116
    • Ehrmann, D.A.1    Schneider, D.J.2    Sobel, B.E.3
  • 37
    • 0032934104 scopus 로고    scopus 로고
    • Effects of a thiazolidinedione compound on body fat and fat distribution of patients with type 2 diabetes
    • Kelly IE, Han TS, Walsh K, et al: Effects of a thiazolidinedione compound on body fat and fat distribution of patients with type 2 diabetes. Diabetes Care 1999; 22:288-293
    • (1999) Diabetes Care , vol.22 , pp. 288-293
    • Kelly, I.E.1    Han, T.S.2    Walsh, K.3
  • 38
    • 0032969421 scopus 로고    scopus 로고
    • Effect of troglitazone on body fat distribution in type 2 diabetic patients
    • Mori Y., Murakawa Y, Okada K, et al: Effect of troglitazone on body fat distribution in type 2 diabetic patients. Diabetes Care 1999; 22:908-912
    • (1999) Diabetes Care , vol.22 , pp. 908-912
    • Mori, Y.1    Murakawa, Y.2    Okada, K.3
  • 39
    • 0033851886 scopus 로고    scopus 로고
    • Efficacy of troglitazone on body fat distribution in type 2 diabetes
    • Akasawa S, Sun F, Ito M, et al: Efficacy of troglitazone on body fat distribution in type 2 diabetes. Diabetes Care 2000; 23:1067-1071
    • (2000) Diabetes Care , vol.23 , pp. 1067-1071
    • Akasawa, S.1    Sun, F.2    Ito, M.3
  • 40
    • 0032913707 scopus 로고    scopus 로고
    • Dyslipidemia of central obesity and insulin resistance
    • Brunzell JD, Hokanson JE: Dyslipidemia of central obesity and insulin resistance. Diabetes Care 1999; 22(suppl 3):C10-C13
    • (1999) Diabetes Care , vol.22 , Issue.SUPPL. 3
    • Brunzell, J.D.1    Hokanson, J.E.2
  • 41
    • 0033929769 scopus 로고    scopus 로고
    • Relationship between regional fat distribution and insulin resistance
    • Bonora E: Relationship between regional fat distribution and insulin resistance. Int J Obes 2000; 24(suppl 2):S32-S35
    • (2000) Int J Obes , vol.24 , Issue.SUPPL. 2
    • Bonora, E.1
  • 42
    • 0030762562 scopus 로고    scopus 로고
    • Treatment with the oral antidiabetic agent troglitazone improves β-cell responses to glucose in subjects with impaired glucose tolerance
    • Cavaghan MK, Ehrmann DA, Byrne MN, et al: Treatment with the oral antidiabetic agent troglitazone improves β-cell responses to glucose in subjects with impaired glucose tolerance. J Clin Invest 1997; 100:530-537
    • (1997) J Clin Invest , vol.100 , pp. 530-537
    • Cavaghan, M.K.1    Ehrmann, D.A.2    Byrne, M.N.3
  • 43
    • 0031767928 scopus 로고    scopus 로고
    • Effect of troglitazone on βcell function, insulin sensitivity, and glycemic control in subjects with type 2 diabetes mellitus
    • Prigeon RL, Kahn SE, Porte D Jr: Effect of troglitazone on βcell function, insulin sensitivity, and glycemic control in subjects with type 2 diabetes mellitus. J Clin Endocrinol Metab 1998; 83:819-823
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 819-823
    • Prigeon, R.L.1    Kahn, S.E.2    Porte D., Jr.3
  • 44
    • 0000920022 scopus 로고    scopus 로고
    • Thiazolidinedione induced recovery of pancreatic beta cell function
    • Ovalle F, Bell DSH: Thiazolidinedione induced recovery of pancreatic beta cell function. Diabetes 2000; 49(suppl 1):A120
    • (2000) Diabetes , vol.49 , Issue.SUPPL. 1
    • Ovalle, F.1    Bell, D.S.H.2
  • 45
    • 0033811933 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in normal human pancreatic islet cells
    • Dubois M, Pattou F, Kerr-Conte J, et al: Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in normal human pancreatic islet cells. Diabetologia 2000; 43:1165-1169
    • (2000) Diabetologia , vol.43 , pp. 1165-1169
    • Dubois, M.1    Pattou, F.2    Kerr-Conte, J.3
  • 46
    • 0033394569 scopus 로고    scopus 로고
    • Short-term treatment with troglitazone decreases bone turnover in patients with type 2 diabetes mellitus
    • Okazaki R, Miura M, Toriumi M, et al: Short-term treatment with troglitazone decreases bone turnover in patients with type 2 diabetes mellitus. Endocrinol J 1999; 46:795-801
    • (1999) Endocrinol J , vol.46 , pp. 795-801
    • Okazaki, R.1    Miura, M.2    Toriumi, M.3
  • 47
    • 0029795871 scopus 로고    scopus 로고
    • The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome
    • Dunaif A, Scott D, Finegood D, et al: The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome. J Clin Endocrinol Metab 1996; 81:3299-3306
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3299-3306
    • Dunaif, A.1    Scott, D.2    Finegood, D.3
  • 48
    • 0030855145 scopus 로고    scopus 로고
    • Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome
    • Ehrmann DA, Schneider DJ, Sobel BE, et al: Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome. J Clin Endocrinol Metab 1997; 82:2108-2116
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2108-2116
    • Ehrmann, D.A.1    Schneider, D.J.2    Sobel, B.E.3
  • 49
    • 8544242764 scopus 로고    scopus 로고
    • Troglitazone ameliorates insulin resistance in patients with Werner's syndrome
    • Izumino K, Sakamaki H, Ishibashi M, et al: Troglitazone ameliorates insulin resistance in patients with Werner's syndrome. J Clin Endocrinol Metab 1997; 82:2391-2395
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2391-2395
    • Izumino, K.1    Sakamaki, H.2    Ishibashi, M.3
  • 50
    • 0034051079 scopus 로고    scopus 로고
    • Effects of troglitazone on insulin sensitivity in HIV-infected patients with protease inhibitor-associated diabetes mellitus
    • Walli R, Michl GM, Muhlbayer D, et al: Effects of troglitazone on insulin sensitivity in HIV-infected patients with protease inhibitor-associated diabetes mellitus. Res Exp Med (Berl) 2000; 199:253-262
    • (2000) Res Exp Med (Berl) , vol.199 , pp. 253-262
    • Walli, R.1    Michl, G.M.2    Muhlbayer, D.3
  • 51
    • 0034663140 scopus 로고    scopus 로고
    • Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes
    • Arioglu E, Duncan-Morin J, Sebring N, et al: Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes. Ann Intern Med 2000; 133:263-274
    • (2000) Ann Intern Med , vol.133 , pp. 263-274
    • Arioglu, E.1    Duncan-Morin, J.2    Sebring, N.3
  • 52
    • 0031595670 scopus 로고    scopus 로고
    • Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells
    • Brockman JA, Gupta RA, Dubois RN: Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells. Gastroenterology 1998; 115:1049-1055
    • (1998) Gastroenterology , vol.115 , pp. 1049-1055
    • Brockman, J.A.1    Gupta, R.A.2    Dubois, R.N.3
  • 53
    • 0033006938 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma induces growth arrest and differentiation markers of human colon cancer cells
    • Kitamura S, Miyazaki Y, Shinomura Y, et al: Peroxisome proliferator-activated receptor gamma induces growth arrest and differentiation markers of human colon cancer cells. Jpn J Cancer Res 1999; 90:75-80
    • (1999) Jpn J Cancer Res , vol.90 , pp. 75-80
    • Kitamura, S.1    Miyazaki, Y.2    Shinomura, Y.3
  • 54
    • 0031671246 scopus 로고    scopus 로고
    • Differentiation and reversal of malignant changes in colon cancer through PPARgamma
    • Sarraf P, Mueller E, Jones D, et al: Differentiation and reversal of malignant changes in colon cancer through PPARgamma. Nat Med 1998; 4:1004-1005
    • (1998) Nat Med , vol.4 , pp. 1004-1005
    • Sarraf, P.1    Mueller, E.2    Jones, D.3
  • 55
    • 0032145363 scopus 로고    scopus 로고
    • Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in-vitro and in-vivo
    • Kubota T, Koshizuka K, Williamson EA, et al: Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in-vitro and in-vivo. Cancer Res 1998; 58:3344-3352
    • (1998) Cancer Res , vol.58 , pp. 3344-3352
    • Kubota, T.1    Koshizuka, K.2    Williamson, E.A.3
  • 56
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • Elstner E, Muller C, Koshizucka K, et al: Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci USA 1998; 95:8806-8811
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8806-8811
    • Elstner, E.1    Muller, C.2    Koshizucka, K.3
  • 57
    • 0033227254 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptor gamma activation in human breast cancer
    • Yee LD, Sabourin CL, Liu L, et al: Peroxisome proliferatoractivated receptor gamma activation in human breast cancer. Int J Oncol 1999; 15:967-973
    • (1999) Int J Oncol , vol.15 , pp. 967-973
    • Yee, L.D.1    Sabourin, C.L.2    Liu, L.3
  • 58
    • 0034161814 scopus 로고    scopus 로고
    • A ligand peroxisome proliferator-activated receptor gamma, retinoids, and prevention of preneoplastic mammary lesions
    • Mehta RG, Wiliamson E, Patel MK, et al: A ligand peroxisome proliferator-activated receptor gamma, retinoids, and prevention of preneoplastic mammary lesions. J Natl Cancer Inst 2000; 92:418-423
    • (2000) J Natl Cancer Inst , vol.92 , pp. 418-423
    • Mehta, R.G.1    Wiliamson, E.2    Patel, M.K.3
  • 59
    • 0034643258 scopus 로고    scopus 로고
    • Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis
    • Tsubouchi Y, Sano H, Kawahito Y, et al: Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis. Biochem Biophys Res Commun 2000; 270:400-405
    • (2000) Biochem Biophys Res Commun , vol.270 , pp. 400-405
    • Tsubouchi, Y.1    Sano, H.2    Kawahito, Y.3
  • 60
    • 0032586875 scopus 로고    scopus 로고
    • Activation of PPARgamma inhibits cell growth and induces apoptosis in human gastric cancer cells
    • Takahashi N, Okumura T, Motomura W, et al: Activation of PPARgamma inhibits cell growth and induces apoptosis in human gastric cancer cells. FEBS Lett 1999; 455:135-139
    • (1999) FEBS Lett , vol.455 , pp. 135-139
    • Takahashi, N.1    Okumura, T.2    Motomura, W.3
  • 61
    • 0034654120 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands inhibit estrogen biosynthesis in human breast adipose tissue: Possible implications for breast cancer therapy
    • Rubin GL, Zhao Y, Kalus AM, et al: Peroxisome proliferator-activated receptor gamma ligands inhibit estrogen biosynthesis in human breast adipose tissue: Possible implications for breast cancer therapy. Cancer Res 2000; 60:1604-1608
    • (2000) Cancer Res , vol.60 , pp. 1604-1608
    • Rubin, G.L.1    Zhao, Y.2    Kalus, A.M.3
  • 62
    • 0033616795 scopus 로고    scopus 로고
    • Induction of solid tumor differentiation by peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma
    • Demetri GD, Fletcher CD, Mueller E, et al: Induction of solid tumor differentiation by peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma. Proc Natl Acad Sci USA 1999; 96:3951-3956
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3951-3956
    • Demetri, G.D.1    Fletcher, C.D.2    Mueller, E.3
  • 63
    • 0003723382 scopus 로고    scopus 로고
    • Morris Plains, NJ, Parke-Davis, Division of Warner Lambert Co.
    • Rezulin (troglitazone) [package insert]. Morris Plains, NJ, Parke-Davis, Division of Warner Lambert Co, 1999
    • (1999) Rezulin (troglitazone) [package insert]
  • 64
    • 0032568261 scopus 로고    scopus 로고
    • Hepatic dysfunction associated with troglitazone
    • Watkins PB, Whitcomb RW: Hepatic dysfunction associated with troglitazone. N Engl J Med 1998; 338:916-917
    • (1998) N Engl J Med , vol.338 , pp. 916-917
    • Watkins, P.B.1    Whitcomb, R.W.2
  • 65
    • 0242278337 scopus 로고    scopus 로고
    • Troglitazone-associated hepatic failure
    • Misbin RI: Troglitazone-associated hepatic failure. Ann Intern Med 1999; 130:330
    • (1999) Ann Intern Med , vol.130 , pp. 330
    • Misbin, R.I.1
  • 66
    • 0032125406 scopus 로고    scopus 로고
    • Two cases of severe clinical and histologic hepatic toxicity associated with troglitazone
    • Gitlin N, Julie NL, Spurr CL, et al: Two cases of severe clinical and histologic hepatic toxicity associated with troglitazone. Ann Intern Med 1998; 129:36-38
    • (1998) Ann Intern Med , vol.129 , pp. 36-38
    • Gitlin, N.1    Julie, N.L.2    Spurr, C.L.3
  • 67
    • 0032125137 scopus 로고    scopus 로고
    • Troglitazone-induced failure leading to liver transplantation
    • Neuschwander-Tetri BA, Isley WI, Oki JC, et al: Troglitazone-induced failure leading to liver transplantation. Ann Intern Med 1998; 129:38-41
    • (1998) Ann Intern Med , vol.129 , pp. 38-41
    • Neuschwander-Tetri, B.A.1    Isley, W.I.2    Oki, J.C.3
  • 68
    • 0032535749 scopus 로고    scopus 로고
    • Fatal hepatotoxicity associated with troglitazone
    • Vella A, de Groen PC, Dinneon SF: Fatal hepatotoxicity associated with troglitazone. Ann Intern Med 1998; 129:1080
    • (1998) Ann Intern Med , vol.129 , pp. 1080
    • Vella, A.1    De Groen, P.C.2    Dinneon, S.F.3
  • 69
    • 0033975372 scopus 로고    scopus 로고
    • Late-onset troglitazone-induced hepatic dysfunction
    • Bell DSH, Ovalle F: Late-onset troglitazone-induced hepatic dysfunction. Diabetes Care 2000; 23:128-129
    • (2000) Diabetes Care , vol.23 , pp. 128-129
    • Bell, D.S.H.1    Ovalle, F.2
  • 70
    • 0033914010 scopus 로고    scopus 로고
    • The rise and fall of troglitazone
    • Bailey CJ: The rise and fall of troglitazone. Diabet Med 2000; 17:414-415
    • (2000) Diabet Med , vol.17 , pp. 414-415
    • Bailey, C.J.1
  • 71
    • 0033984428 scopus 로고    scopus 로고
    • Hepatic failure in a patient taking rosiglitazone
    • Forman L, Dimmans DA, Diamond RH: Hepatic failure in a patient taking rosiglitazone. Ann Intern Med 2000; 132:118-121
    • (2000) Ann Intern Med , vol.132 , pp. 118-121
    • Forman, L.1    Dimmans, D.A.2    Diamond, R.H.3
  • 72
    • 0033972218 scopus 로고    scopus 로고
    • Hepatocellular injury in a patient receiving rosiglitazone: A case report
    • Al-Salman J, Arjomand H, Kemp DG, et al: Hepatocellular injury in a patient receiving rosiglitazone: A case report. Ann Intern Med 2000; 132:121-124
    • (2000) Ann Intern Med , vol.132 , pp. 121-124
    • Al-Salman, J.1    Arjomand, H.2    Kemp, D.G.3
  • 75
    • 0004325228 scopus 로고    scopus 로고
    • Lincolnshire, III, Takeda Pharmaceutical of America Inc.
    • Actos (pioglitazone) [package insert]. Lincolnshire, III, Takeda Pharmaceutical of America Inc, 2000
    • (2000) Actos (pioglitazone) [package insert]
  • 76
    • 0031581509 scopus 로고    scopus 로고
    • Increase of lipoprotein (a) with troglitazone
    • Matsumoto K, Miyake S, Yano M, et al: Increase of lipoprotein (a) with troglitazone. Lancet 1997; 350:1748-1749
    • (1997) Lancet , vol.350 , pp. 1748-1749
    • Matsumoto, K.1    Miyake, S.2    Yano, M.3
  • 77
    • 0032930211 scopus 로고    scopus 로고
    • Troglitazone's effect on lipoprotein (a) levels
    • Ovalle F, Bell DSH: Troglitazone's effect on lipoprotein (a) levels. Diabetes Care 1999; 22:859-860
    • (1999) Diabetes Care , vol.22 , pp. 859-860
    • Ovalle, F.1    Bell, D.S.H.2
  • 78
    • 0002013864 scopus 로고
    • Subchronic toxicity of the thiazolidinedione Tanabe-174 (LY282449), in the rat and dog
    • Williams GD, Deldar A, Jordan WH, et al: Subchronic toxicity of the thiazolidinedione Tanabe-174 (LY282449), in the rat and dog. Diabetes 1993; 42:186A
    • (1993) Diabetes , vol.42
    • Williams, G.D.1    Deldar, A.2    Jordan, W.H.3
  • 79
    • 0033598091 scopus 로고    scopus 로고
    • Pulmonary edema associated with troglitazone therapy
    • Hirsch IB, Kelly J, Cooper S: Pulmonary edema associated with troglitazone therapy. Arch Intern Med 1999; 159:1811
    • (1999) Arch Intern Med , vol.159 , pp. 1811
    • Hirsch, I.B.1    Kelly, J.2    Cooper, S.3
  • 80
    • 0033545194 scopus 로고    scopus 로고
    • Significant weight gain with Rezulin therapy
    • Gorson DM: Significant weight gain with Rezulin therapy. Arch Intern Med 1999; 159:99
    • (1999) Arch Intern Med , vol.159 , pp. 99
    • Gorson, D.M.1
  • 81
    • 0032855543 scopus 로고    scopus 로고
    • Troglitazone-induced heart and adipose tissue cell proliferation in mice
    • Breider MA, Gough AW, Haskins JR, et al: Troglitazone-induced heart and adipose tissue cell proliferation in mice. Toxicol Pathol 1999; 27:545-552
    • (1999) Toxicol Pathol , vol.27 , pp. 545-552
    • Breider, M.A.1    Gough, A.W.2    Haskins, J.R.3
  • 82
    • 0032970818 scopus 로고    scopus 로고
    • P53 is not inactivated in B6C3F1 mouse vascular tumors arising spontaneously or associated with long-term administration of the thiazolidinedione troglitazone
    • Duddy SK, Parker RF, Bleavins MR, et al: P53 is not inactivated in B6C3F1 mouse vascular tumors arising spontaneously or associated with long-term administration of the thiazolidinedione troglitazone. Toxicol Appl Pharmacol 1999; 156:106-112
    • (1999) Toxicol Appl Pharmacol , vol.156 , pp. 106-112
    • Duddy, S.K.1    Parker, R.F.2    Bleavins, M.R.3
  • 83
    • 0033571775 scopus 로고    scopus 로고
    • Human uterine leiomyomata express higher levels of peroxisome proliferator-activated receptor gamma, retinoid X receptor alpha, and all-trans retinoic acid than myometrium
    • Tsibris JC, Porter KB, Jazayeri A, et al: Human uterine leiomyomata express higher levels of peroxisome proliferator-activated receptor gamma, retinoid X receptor alpha, and all-trans retinoic acid than myometrium. Cancer Res 1999; 59:5737-5744
    • (1999) Cancer Res , vol.59 , pp. 5737-5744
    • Tsibris, J.C.1    Porter, K.B.2    Jazayeri, A.3
  • 84
    • 0031694577 scopus 로고    scopus 로고
    • Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APC-/+ mice
    • Lefebvre A, Chen I, Desreumaux P, et al: Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APC-/+ mice. Nat Med 1998; 4:1053-1057
    • (1998) Nat Med , vol.4 , pp. 1053-1057
    • Lefebvre, A.1    Chen, I.2    Desreumaux, P.3
  • 85
    • 0031667938 scopus 로고    scopus 로고
    • Activators of the nuclear receptor PPARgmnma enhance colon polyp formation
    • Saez E, Tontonoz P, Nelson MC, et al: Activators of the nuclear receptor PPARgmnma enhance colon polyp formation. Nat Med 1998; 4:1058-1061
    • (1998) Nat Med , vol.4 , pp. 1058-1061
    • Saez, E.1    Tontonoz, P.2    Nelson, M.C.3


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