Bertosamil blocks HERG potassium channels in their open and inactivated states

British Journal of Pharmacology

Volumn 137, Issue 2, 2002, Pages 221-228

  Zitron, Edgar ^a   Karle, Christoph A ^a   Wendt Nordahl, Gunnar ^a   Kathöfer, Sven ^a   Zhang, Wei ^a   Thomas, Dierk ^a   Weretka, Slawomir ^a   Kiehn, Johann ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Anti arrhythmic drug; Bertosamil; HERG; Two electrode voltage clamp; Xenopus oocytes

Indexed keywords

AMIODARONE; AZIMILIDE; BERTOSAMIL; CARVEDILOL; CLOFILIUM; DOFETILIDE; ETHYLHEPTYL[4 (4 NITROPHENYL)BUTYL]AMINE; HALOPERIDOL; N (3,4 DIMETHOXYPHENYL) N [3 [N [2 (3,4 DIMETHOXYPHENYL)ETHYL] N METHYLAMINO]PROPYL] 4 NITROBENZAMIDE; POTASSIUM CHANNEL; SOTALOL; TEDISAMIL; TERFENADINE; TERIKALANT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; ELECTRIC POTENTIAL; GENE; HUMAN ETHER A GO GO RELATED GENE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CATION TRANSPORT PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; RECOMBINANT PROTEINS; XENOPUS;

EID: 0036737544     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704859     Document Type: Article

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