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Volumn 72, Issue 4, 2000, Pages 477-484

Fluorometric analysis of DNA unwinding (FADU) as a method for detecting repair-induced DNA strand breaks in UV-irradiated mammalian cells

Author keywords

[No Author keywords available]

Indexed keywords

APHIDICOLIN; BISBENZIMIDE; DNA TOPOISOMERASE; DOUBLE STRANDED DNA; SODIUM HYDROXIDE;

EID: 0034309750     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/0031-8655(2000)072<0477:FAODUF>2.0.CO;2     Document Type: Article
Times cited : (44)

References (48)
  • 1
    • 0033039119 scopus 로고    scopus 로고
    • A population-based survey on the use of artificial tanning devices in the Province of Quebec, Canada
    • Rhainds, M., L. De Guire and J. Claveau (1999) A population-based survey on the use of artificial tanning devices in the Province of Quebec, Canada. J. Am. Acad. Dermatol. 40, 572-576.
    • (1999) J. Am. Acad. Dermatol. , vol.40 , pp. 572-576
    • Rhainds, M.1    De Guire, L.2    Claveau, J.3
  • 2
    • 0345196540 scopus 로고    scopus 로고
    • Photochemical genotoxicity and photochemical carcinogenesis-two sides of a coin?
    • Muller, L., P. Kasper, B. Kersten and J. Zhang (1998) Photochemical genotoxicity and photochemical carcinogenesis-two sides of a coin? Toxicol. Lett. 102-103, 383-387.
    • (1998) Toxicol. Lett. , vol.102-103 , pp. 383-387
    • Muller, L.1    Kasper, P.2    Kersten, B.3    Zhang, J.4
  • 4
    • 0023552962 scopus 로고
    • Mutagenic and lethal effects of near-ultraviolet radiation (290-400 nm) on bacteria and phage
    • Eisenstark, A. (1987) Mutagenic and lethal effects of near-ultraviolet radiation (290-400 nm) on bacteria and phage. Environ. Mol. Mutagen. 10, 317-337.
    • (1987) Environ. Mol. Mutagen. , vol.10 , pp. 317-337
    • Eisenstark, A.1
  • 5
    • 0026749547 scopus 로고
    • Inherited defects in DNA repair and susceptibility to DNA-damaging agents
    • Hansson, J. (1992) Inherited defects in DNA repair and susceptibility to DNA-damaging agents. Toxicol. Lett. 64-65, 141-148.
    • (1992) Toxicol. Lett. , vol.64-65 , pp. 141-148
    • Hansson, J.1
  • 6
    • 0030820485 scopus 로고    scopus 로고
    • Human cancer and DNA repair-deficient diseases
    • Sarasin, A. and A. Stary (1997) Human cancer and DNA repair-deficient diseases. Cancer Detect. Prev. 21, 406-411.
    • (1997) Cancer Detect. Prev. , vol.21 , pp. 406-411
    • Sarasin, A.1    Stary, A.2
  • 7
    • 0032501178 scopus 로고    scopus 로고
    • UV-induced mutations and skin cancer: How important is the link?
    • Bridges, B. A. (1998) UV-induced mutations and skin cancer: how important is the link? Mutat. Res. 422, 23-30.
    • (1998) Mutat. Res. , vol.422 , pp. 23-30
    • Bridges, B.A.1
  • 8
    • 0025374911 scopus 로고
    • Prediction of the radiation sensitivity of human squamous cell carcinoma cells using DNA filter elution
    • Schwartz, J. L., R. Mustafi, M. A. Beckett and R. R. Weichselbaum (1990) Prediction of the radiation sensitivity of human squamous cell carcinoma cells using DNA filter elution. Radiat. Res. 123, 1-6.
    • (1990) Radiat. Res. , vol.123 , pp. 1-6
    • Schwartz, J.L.1    Mustafi, R.2    Beckett, M.A.3    Weichselbaum, R.R.4
  • 10
    • 0030569251 scopus 로고    scopus 로고
    • Radioadaptive response: Efficient repair of radiation-induced DNA damage in adapted cells
    • Ikushima, T., H. Aritomi and J. Morisita (1996) Radioadaptive response: efficient repair of radiation-induced DNA damage in adapted cells. Mutat. Res. 358, 193-198.
    • (1996) Mutat. Res. , vol.358 , pp. 193-198
    • Ikushima, T.1    Aritomi, H.2    Morisita, J.3
  • 11
    • 0026774634 scopus 로고
    • X-ray induced DNA strand break induction and rejoining in cultured bovine lens epithelial cells
    • Baumstark-Khan, C., E. Aufderheide and H. Rink (1992) X-ray induced DNA strand break induction and rejoining in cultured bovine lens epithelial cells. Opthalmic Res. 24, 220-227.
    • (1992) Opthalmic Res. , vol.24 , pp. 220-227
    • Baumstark-Khan, C.1    Aufderheide, E.2    Rink, H.3
  • 12
    • 0015598569 scopus 로고
    • Radiation induced strand breakage in DNA from mammalian cells. Strand separation in alkaline solution
    • Ahnstrøm, G. and K. Erixon (1973) Radiation induced strand breakage in DNA from mammalian cells. Strand separation in alkaline solution. Int. J. Radiat. Biol. 23, 285-289.
    • (1973) Int. J. Radiat. Biol. , vol.23 , pp. 285-289
    • Ahnstrøm, G.1    Erixon, K.2
  • 13
    • 0016425915 scopus 로고
    • The rate of strand separation in alkali of DNA of irradiated mammalian cells
    • Rydberg, B. (1975) The rate of strand separation in alkali of DNA of irradiated mammalian cells. Radiat. Res. 61, 274-287.
    • (1975) Radiat. Res. , vol.61 , pp. 274-287
    • Rydberg, B.1
  • 14
    • 0026456789 scopus 로고
    • Comparison of DNA strand break induction in CHO cells measured by alkaline elution and by fluorometric analysis of DNA unwinding (FADU)
    • Baumstark-Khan, C., U. Griesenbach and H. Rink (1992) Comparison of DNA strand break induction in CHO cells measured by alkaline elution and by fluorometric analysis of DNA unwinding (FADU). Free Radic. Res. Commun. 16, 381-389.
    • (1992) Free Radic. Res. Commun. , vol.16 , pp. 381-389
    • Baumstark-Khan, C.1    Griesenbach, U.2    Rink, H.3
  • 15
    • 0027948421 scopus 로고
    • Alkaline elution versus fluorescence analysis of DNA unwinding
    • Baumstark-Khan, C. (1994) Alkaline elution versus fluorescence analysis of DNA unwinding. Methods Enzymol. 234, 88-102.
    • (1994) Methods Enzymol. , vol.234 , pp. 88-102
    • Baumstark-Khan, C.1
  • 16
    • 0025127634 scopus 로고
    • Fluorometric analysis of DNA unwinding to study strand breaks and repair in mammalian cells
    • Birnboim, H. C. (1990) Fluorometric analysis of DNA unwinding to study strand breaks and repair in mammalian cells. Methods Enzymol. 186, 550-555.
    • (1990) Methods Enzymol. , vol.186 , pp. 550-555
    • Birnboim, H.C.1
  • 17
    • 0014031359 scopus 로고
    • Reconstruction in vivo of irradiated Escherichia coli deoxyribonucleic acid; the rejoining of broken pieces
    • McGrath, R. A. and R. Williams (1966) Reconstruction in vivo of irradiated Escherichia coli deoxyribonucleic acid; the rejoining of broken pieces. Nature 212, 534-535.
    • (1966) Nature , vol.212 , pp. 534-535
    • McGrath, R.A.1    Williams, R.2
  • 18
    • 0015802743 scopus 로고
    • Alkaline elution analysis, a new approach to the study of DNA single-strand interruptions in cells
    • Kohn, K. W. and R. A. Grimek-Ewig (1973) Alkaline elution analysis, a new approach to the study of DNA single-strand interruptions in cells. Cancer Res. 33, 1849-1853.
    • (1973) Cancer Res. , vol.33 , pp. 1849-1853
    • Kohn, K.W.1    Grimek-Ewig, R.A.2
  • 19
    • 0018787368 scopus 로고
    • X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution
    • Bradley, M. O. and K. W. Kohn (1979) X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution. Nucleic Acids Res. 7, 793-804.
    • (1979) Nucleic Acids Res. , vol.7 , pp. 793-804
    • Bradley, M.O.1    Kohn, K.W.2
  • 20
    • 0021153574 scopus 로고
    • Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis
    • Schwartz, D. C. and D. R. Cantor (1984) Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis. Cell 37, 67-75.
    • (1984) Cell , vol.37 , pp. 67-75
    • Schwartz, D.C.1    Cantor, D.R.2
  • 21
    • 0022549765 scopus 로고
    • Electrophoretic separations of large DNA molecules by periodic inversion of the electric field
    • Carle, G. F., M. Frank and M. V. Olson (1986) Electrophoretic separations of large DNA molecules by periodic inversion of the electric field. Science 232, 65-68.
    • (1986) Science , vol.232 , pp. 65-68
    • Carle, G.F.1    Frank, M.2    Olson, M.V.3
  • 22
    • 0019476174 scopus 로고
    • Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation
    • Birnboim, H. C. and J. J. Jevcak (1981) Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation. Cancer Res. 41, 1889-1892.
    • (1981) Cancer Res. , vol.41 , pp. 1889-1892
    • Birnboim, H.C.1    Jevcak, J.J.2
  • 23
    • 0029053910 scopus 로고
    • Induction of single strand DNA breaks in workers professionally exposed to polycyclic aromatic hydrocarbons
    • Salagovic, J., I. Kalina and K. Dubayova (1995) Induction of single strand DNA breaks in workers professionally exposed to polycyclic aromatic hydrocarbons. Neoplasma 42, 115-118.
    • (1995) Neoplasma , vol.42 , pp. 115-118
    • Salagovic, J.1    Kalina, I.2    Dubayova, K.3
  • 24
    • 0026792559 scopus 로고
    • Detection by fluorescence analysis of DNA unwinding and unscheduled DNA synthesis of DNA damage and repair induced in vitro by direct-acting mutagens on human lymphocytes
    • Celotti, L., P. Ferraro and M. R. Biasin (1992) Detection by fluorescence analysis of DNA unwinding and unscheduled DNA synthesis of DNA damage and repair induced in vitro by direct-acting mutagens on human lymphocytes. Mutat. Res. 281, 17-23.
    • (1992) Mutat. Res. , vol.281 , pp. 17-23
    • Celotti, L.1    Ferraro, P.2    Biasin, M.R.3
  • 25
    • 0000695308 scopus 로고
    • Measurement of strand breaks by alkaline denaturation and hydroxyapatite chromatography
    • Edited by E. C. Friedberg and P. C. Hanawalt. Marcel Dekker Inc., New York
    • Ahnstrøm, G. and K. Exrixon (1981) Measurement of strand breaks by alkaline denaturation and hydroxyapatite chromatography. In DNA Repair. A Laboratory Manual of Research Procedures, Vol. 1, Part B (Edited by E. C. Friedberg and P. C. Hanawalt), pp. 403-418. Marcel Dekker Inc., New York.
    • (1981) DNA Repair. A Laboratory Manual of Research Procedures , vol.1 , Issue.PART B , pp. 403-418
    • Ahnstrøm, G.1    Exrixon, K.2
  • 26
    • 0024493214 scopus 로고
    • Fluorescence labeling and microscopy of DNA
    • Arndt-Jovin, D. J. and T. M. Jovin (1989) Fluorescence labeling and microscopy of DNA. Methods Cell Biol. 30, 417-448.
    • (1989) Methods Cell Biol. , vol.30 , pp. 417-448
    • Arndt-Jovin, D.J.1    Jovin, T.M.2
  • 27
    • 0025006448 scopus 로고
    • Binding characteristics of Hoechst 33258 with calf thymus DNA, poly[d(A-T)] and d(CCGGAATTCCGG): Multiple stoichiometries and determination of tight binding with a wide spectrum of site affinities
    • Loontiens, F. G., P. Regenfuss, A. Zechel, L. Dumortier and R. M. Clegg (1990) Binding characteristics of Hoechst 33258 with calf thymus DNA, poly[d(A-T)] and d(CCGGAATTCCGG): multiple stoichiometries and determination of tight binding with a wide spectrum of site affinities. Biochemistry 29, 9029-9039.
    • (1990) Biochemistry , vol.29 , pp. 9029-9039
    • Loontiens, F.G.1    Regenfuss, P.2    Zechel, A.3    Dumortier, L.4    Clegg, R.M.5
  • 28
    • 0028914052 scopus 로고
    • Linear induction of DNA double-strand breakage with X-ray dose, as determined from DNA fragment size distribution
    • Erixon, K. and B. Cedervall (1995) Linear induction of DNA double-strand breakage with X-ray dose, as determined from DNA fragment size distribution. Radiat. Res. 142, 153-162.
    • (1995) Radiat. Res. , vol.142 , pp. 153-162
    • Erixon, K.1    Cedervall, B.2
  • 29
    • 0032128265 scopus 로고    scopus 로고
    • Chinese hamster cells meet DNA repair: An entirely acceptable affair
    • Thompson, L. H. (1998) Chinese hamster cells meet DNA repair: an entirely acceptable affair. Bioessays 20, 589-597.
    • (1998) Bioessays , vol.20 , pp. 589-597
    • Thompson, L.H.1
  • 30
    • 0019991171 scopus 로고
    • A fluorescence enhancement assay for cellular DNA damage
    • Kanter, P. M. and H. S. Schwartz (1982) A fluorescence enhancement assay for cellular DNA damage. Mol. Pharmacol. 22, 145-151.
    • (1982) Mol. Pharmacol. , vol.22 , pp. 145-151
    • Kanter, P.M.1    Schwartz, H.S.2
  • 31
    • 0025141001 scopus 로고
    • Topological DNA target size model
    • Suciu, D. (1990) Topological DNA target size model. Radiat. Environ. Biophys. 29, 203-211.
    • (1990) Radiat. Environ. Biophys. , vol.29 , pp. 203-211
    • Suciu, D.1
  • 32
    • 0027407971 scopus 로고
    • X-ray-induced DNA double-strand breaks as lethal lesions in diploid human fibroblasts compared to Chinese hamster ovary cells
    • Baumstark-Khan, C. (1993) X-ray-induced DNA double-strand breaks as lethal lesions in diploid human fibroblasts compared to Chinese hamster ovary cells. Int. J. Radiat. Biol. 63, 305-311.
    • (1993) Int. J. Radiat. Biol. , vol.63 , pp. 305-311
    • Baumstark-Khan, C.1
  • 33
    • 0018857985 scopus 로고
    • Aphidicolin allows a rapid and simple evaluation of DNA-repair synthesis in damaged human cells
    • Pedrali-Noy, G. and S. Spadari (1980) Aphidicolin allows a rapid and simple evaluation of DNA-repair synthesis in damaged human cells. Mutat. Res. 70, 389-394.
    • (1980) Mutat. Res. , vol.70 , pp. 389-394
    • Pedrali-Noy, G.1    Spadari, S.2
  • 34
    • 0027218416 scopus 로고
    • Aphidicolin inhibits excision repair of UV-induced pyrimidine photodimers in low serum cultures of mitotic and mitomycin C-induced postmitotic human skin fibroblasts
    • Niggli, H. J. (1993) Aphidicolin inhibits excision repair of UV-induced pyrimidine photodimers in low serum cultures of mitotic and mitomycin C-induced postmitotic human skin fibroblasts. Mutat. Res. 295, 125-133.
    • (1993) Mutat. Res. , vol.295 , pp. 125-133
    • Niggli, H.J.1
  • 35
    • 0026584930 scopus 로고
    • Effect of aphidicolin on DNA synthesis, PLD-recovery and DNA repair of human diploid fibroblasts
    • Baumstark-Khan, C. (1992) Effect of aphidicolin on DNA synthesis, PLD-recovery and DNA repair of human diploid fibroblasts. Int. J. Radiat. Biol. 61, 191-197.
    • (1992) Int. J. Radiat. Biol. , vol.61 , pp. 191-197
    • Baumstark-Khan, C.1
  • 36
    • 0028170923 scopus 로고
    • Molecular analysis of CXPD mutations in the repair-deficient hamster mutants UV5 and UVL-13
    • Weber, C. A., J. M. Kirchner, E. P. Salazar and K. Takayama (1994) Molecular analysis of CXPD mutations in the repair-deficient hamster mutants UV5 and UVL-13. Mutat. Res. 324, 147-152.
    • (1994) Mutat. Res. , vol.324 , pp. 147-152
    • Weber, C.A.1    Kirchner, J.M.2    Salazar, E.P.3    Takayama, K.4
  • 37
    • 0031424869 scopus 로고    scopus 로고
    • Restoration of preferential and strand specific gene repair in group 2 Chinese hamster ovary mutants (UV5) by the XPD (ERCC2) gene
    • Cullinane, C., C. A. Weber, G. Dianov and V. A. Bohr (1997) Restoration of preferential and strand specific gene repair in group 2 Chinese hamster ovary mutants (UV5) by the XPD (ERCC2) gene. Carcinogenesis 18, 681-686.
    • (1997) Carcinogenesis , vol.18 , pp. 681-686
    • Cullinane, C.1    Weber, C.A.2    Dianov, G.3    Bohr, V.A.4
  • 38
    • 0030606245 scopus 로고    scopus 로고
    • The non-random distribution of UV-induced photoproducts in the nuclear matrix and non-matrix DNA fractions
    • Widlak, P., V. J. Bykov, K. Hemminki and J. Rzeszowska-Wolny (1996) The non-random distribution of UV-induced photoproducts in the nuclear matrix and non-matrix DNA fractions. Cancer Lett. 108, 215-223.
    • (1996) Cancer Lett. , vol.108 , pp. 215-223
    • Widlak, P.1    Bykov, V.J.2    Hemminki, K.3    Rzeszowska-Wolny, J.4
  • 42
    • 0029932913 scopus 로고    scopus 로고
    • The in situ repair kinetics of epidermal thymine dimers and 6-4 photoproducts in human skin types I and II
    • Young, A. R., C. A. Chadwick, G. I. Harrison, J. L. Hawk, O. Nikaido and C. S. Potten (1996) The in situ repair kinetics of epidermal thymine dimers and 6-4 photoproducts in human skin types I and II. J. Investig. Dermatol. 106, 1307-1313.
    • (1996) J. Investig. Dermatol. , vol.106 , pp. 1307-1313
    • Young, A.R.1    Chadwick, C.A.2    Harrison, G.I.3    Hawk, J.L.4    Nikaido, O.5    Potten, C.S.6
  • 43
    • 0030027286 scopus 로고    scopus 로고
    • Comparison of the rate of excision of major UV photoproducts in the strands of the human HPRT gene of normal and xeroderma pigmentosum variant cells
    • Tung, B. S., W. G. McGregor, Y. C. Wang, V. M. Maher and J. J. McCormick (1996) Comparison of the rate of excision of major UV photoproducts in the strands of the human HPRT gene of normal and xeroderma pigmentosum variant cells. Mutat. Res. 362, 65-74.
    • (1996) Mutat. Res. , vol.362 , pp. 65-74
    • Tung, B.S.1    McGregor, W.G.2    Wang, Y.C.3    Maher, V.M.4    McCormick, J.J.5
  • 44
    • 0029923890 scopus 로고    scopus 로고
    • Use of the alkaline comet assay to detect DNA repair deficiencies in human fibroblasts exposed to UVC, UVB, UVA and gamma-rays
    • Alapetite, C., T. Wachter, E. Sage and E. Moustacchi (1996) Use of the alkaline comet assay to detect DNA repair deficiencies in human fibroblasts exposed to UVC, UVB, UVA and gamma-rays. Int. J. Radiat. Biol. 69, 359-369.
    • (1996) Int. J. Radiat. Biol. , vol.69 , pp. 359-369
    • Alapetite, C.1    Wachter, T.2    Sage, E.3    Moustacchi, E.4
  • 45
    • 0032150521 scopus 로고    scopus 로고
    • Individual radiosensitivity and DNA repair proficiency: The value of the comet assay
    • Alapetite, C. (1998) Individual radiosensitivity and DNA repair proficiency: the value of the comet assay. Cancer Radiother. 2, 534-540.
    • (1998) Cancer Radiother. , vol.2 , pp. 534-540
    • Alapetite, C.1
  • 46
    • 0026501421 scopus 로고
    • UV-C sensitivity of unstimulated and stimulated human lymphocytes from normal and xeroderma pigmentosum donors in the comet assay: A potential diagnostic technique
    • Green, M. H., J. E. Lowe, S. A. Harcourt, P. Akinluyi, T. Rowe, J. Cole, A. V. Anstey and C. F. Arlett (1992) UV-C sensitivity of unstimulated and stimulated human lymphocytes from normal and xeroderma pigmentosum donors in the comet assay: a potential diagnostic technique. Mutat. Res. 273, 137-144.
    • (1992) Mutat. Res. , vol.273 , pp. 137-144
    • Green, M.H.1    Lowe, J.E.2    Harcourt, S.A.3    Akinluyi, P.4    Rowe, T.5    Cole, J.6    Anstey, A.V.7    Arlett, C.F.8
  • 47
    • 0029954286 scopus 로고    scopus 로고
    • UV- and gamma-irradiation-induced DNA single-strand breaks and their repair in human blood granulocytes and lymphocytes
    • Lankinen, M. H., L. M. Vilpo and J. A. Vilpo (1996) UV- and gamma-irradiation-induced DNA single-strand breaks and their repair in human blood granulocytes and lymphocytes. Mutat. Res. 352, 31-38.
    • (1996) Mutat. Res. , vol.352 , pp. 31-38
    • Lankinen, M.H.1    Vilpo, L.M.2    Vilpo, J.A.3
  • 48
    • 0029788623 scopus 로고    scopus 로고
    • Complex repair kinetics of DNA strand breaks induced by gamma-rays of UV radiation in Ehrlich ascites tumour cells
    • Mlejnek P. and S. Kozubek (1996) Complex repair kinetics of DNA strand breaks induced by gamma-rays of UV radiation in Ehrlich ascites tumour cells. Radiat. Environ. Biophys. 35, 171-177.
    • (1996) Radiat. Environ. Biophys. , vol.35 , pp. 171-177
    • Mlejnek, P.1    Kozubek, S.2


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