Dextro-naloxone counteracts amphetamine-induced hyperactivity

Pharmacology Biochemistry and Behavior

Volumn 59, Issue 2, 1998, Pages 271-274

  Chatterjie, N ^a   Sechzer, A ^b   Lieberman, K W ^c   Alexander, G J ^a  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^b PACE UNIVERSITY   (United States)

^c RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

(+) Naloxone; Amphetamine; d Naloxone; Dextro Naloxone; Hperactivity; l Naloxone; Locomotor activity

Indexed keywords

AMPHETAMINE; NALOXONE; OPIATE; OPIATE ANTAGONIST; OPIATE RECEPTOR;

AGITATION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENANTIOMER; HYPERACTIVITY; LOCOMOTION; MALE; MOTOR ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AMPHETAMINE; ANIMALS; BEHAVIOR, ANIMAL; DOPAMINE AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MORPHINE; MOTOR ACTIVITY; NALOXONE; NARCOTIC ANTAGONISTS; NARCOTICS; STEREOISOMERISM;

EID: 0032005819     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(97)00528-5     Document Type: Article

References (19)

1. Alexander G. J. Lethality of pentylenetetrazol in rats after depletion of brain norepinephrine. Fed. Proc. 36:1977;354.
2. Alexander G. J., Kopeloff L. M. Effects of 6-hydroxydopamine. Delayed motor manifestation associated with high mortality in rodents. Neurochem. Res. 3:1978;821-825.
3. Alexander G. J., Chatterjie N. Spontaneous motility in SW mice. Amphetamine/naloxone antagonism FASEB J. 5:1991;A862.
4. Alexander G. J., Chatterjie N. Non-opiate effects of naloxone. Antagonism of amphetamine-induced spontaneous activity in SW mice FASEB J. 6:1992;A994.
5. Borowski N. F., Kokkinidis L. Long-term influence of d-amphetamine on mesolimbic brain-stimulation reward. Comparison of chronic haloperolidol and naloxone effects Pharmacol. Biochem. Behav. 43:1992;1-15.
6. Brasch H. Influence of optical isomers of (+)- and (-)-naloxone on beating frequency, contractile force and action potentials of guinea pig isolated cardiac preparation. Br. J. Pharmacol. 88:1986;733-740.
7. Chatterjie N., Alexander G. J. Dextro-naloxone antagonizes amphetamine-induced increase in spontaneous motility. FASEB J. 5:1991;A862.
8. Chatterjie N., Alexander G. J. Stereochemical results of the Bucherer-Bergs reaction in the 14-hydroxydihydromorphinone series. Res. Commun. Subst. Abuse. 12:1991;132-143.
9. Chatterjie N., Alexander G. J. Diastereomeric forms of benzoylhydrazone and hydantoin derivatives of opiate agonists and antagonists. FASEB J. 8:1994;A1466.
10. Chatterjie N., Alexander G. J., Sechzer J. A., Lieberman K. W. Prevention of cocaine-induced hyperactivity by a naloxone isomer with no opiate antagonist activity. Neurochem. Res. 21:1996;691-693.
11. Dunwoodie T. V., Peres-Reyes E., Rice K. C. Stereospecificity of opiate antagonists in rat hippocampus and neocortex responses to (+)- and (-)-isomers of naloxone. Neuroscience. 7:1982;1691-1702.
12. Hooks M. S., Jones D. N., Justice J. B. Jr. Naloxone reduces amphetamine-induced stimulation of locomotor activity and in vivo dopamine release in the striatum and nucleus accumbens. Pharmacol. Biochem. Behav. 41:1992;449-453.
13. Iijima I., Minamikawa J., Jacobson A. E. Studies in the (+)-morphinan series. 5. Synthesis and biological properties of(+):1987;398-400.
14. Jones D. N., Holtzman S. G. Effects of naloxone infusion upon spontaneous and amphetamine-induced activity. Eur. J. Pharmacol. 221:1992;161-165.
15. Jones D. N., Holtzman S. G. Interaction between opioid antagonists and amphetamine. Evidence for mediation by central delta opioid receptors J. Pharmacol. Exp. Ther. 262:1992;638-645.
16. Jones D. N., Holtzman S. G. Influence of naloxone upon motor activity induced by psychomotor stimulant drugs. Psychopharmacology (Berlin). 114:1994;215-224.
17. Rosetti Z. L., Hmaidan Y., Gessa G. L. Marked inhibition of mesolimbic dopamine release. A common feature of ethanol, morphine, cocaine and amphetamine Eur. J. Pharmacol. 221:1992;227-234.
18. Sarne Y., Hochman I., Eshed M. Antiarrhythmic action of naloxone. Direct, non-opiate effect on the rat heart Life Sci. 43:1988;859-864.
19. Valentino R. J., Katz J. L., Mezhihradsky F. Receptor bonding, antagonist and withdrawal-precipitating properties of opiate antagonists. Life Sci. 32:1983;2887-2896.