Drosophila melanogaster dihydroorotate dehydrogenase: The N-terminus is important for biological function in vivo but not for catalytic properties in vitro

Insect Biochemistry and Molecular Biology

Volumn 32, Issue 9, 2002, Pages 1159-1169

  Löffler, Monika ^a   Knecht, Wolfgang ^a,b   Rawls, John ^c   Ullrich, Alexandra ^a   Dietz, Carsten ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Dihydroorotate dehydrogenase; Drosophila melanogaster; Inhibitors; Mitochondria; Protein expression; Transgenic

Indexed keywords

2 (3,3 DICHLOROALLYL) 3 HYDROXY 1,4 NAPHTHOQUINONE; BREQUINAR; DIHYDROOROTATE DEHYDROGENASE; ENZYME INHIBITOR; FLAVOPROTEIN; IMMUNOGLOBULIN; PYRIMIDINE; RECOMBINANT ENZYME; REDOXAL; TERIFLUNOMIDE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CELLULAR DISTRIBUTION; DROSOPHILA MELANOGASTER; DRUG EFFICACY; ENZYME ANALYSIS; ENZYME PURIFICATION; ESCHERICHIA COLI; FUNCTIONAL ASSESSMENT; GENE MUTATION; GENETIC ENGINEERING; INSECT DEVELOPMENT; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STABILITY; PYRIMIDINE SYNTHESIS; TRANSGENE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; CATALYSIS; DROSOPHILA MELANOGASTER; ESCHERICHIA COLI; GENE EXPRESSION; KINETICS; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; RECOMBINANT FUSION PROTEINS;

DROSOPHILA MELANOGASTER; ESCHERICHIA COLI; INSECTA; MELANOGASTER;

EID: 0036713347     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0965-1748(02)00052-8     Document Type: Article

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