Recombinant expression of n-terminal truncated mutants of the membrane bound mouse, rat and human flavoenzyme dihydroorotate dehydrogenase: A versatile tool to rate inhibitor effects?

European Journal of Biochemistry

Volumn 268, Issue 6, 2001, Pages 1861-1868

  Ullrich, Alexandra ^a   Knecht, Wolfgang ^b   Fries, Markus ^a   Löffler, Monika ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Dihydroorotate dehydrogenase; Immunosuppression; Kinetics; Mouse; Mutant protein expression

Indexed keywords

2 CYANO 3 HYDROXY N [4 (TRIFLUOROMETHYL)PHENYL] 6 HEPTYNAMIDE; 2 CYANO N (4 CYANOPHENYL) 3 CYCLOPROPYL 3 OXOPROPIONAMIDE; BENZIDINE DERIVATIVE; BREQUINAR; DETERGENT; DIHYDROOROTATE DEHYDROGENASE; DIHYDROOROTIC ACID DERIVATIVE; ENZYME INHIBITOR; FLAVOPROTEIN; MALONONITRILAMIDE; MEMBRANE ENZYME; MUTANT PROTEIN; NSC 73735; RECOMBINANT ENZYME; REDOXAL; TERIFLUNOMIDE; UBIQUINONE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANALYTIC METHOD; ARTICLE; AUTOIMMUNE DISEASE; CARBOXY TERMINAL SEQUENCE; CARCINOMA; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME SPECIFICITY; GENE CONSTRUCT; HUMAN; HYDROPHOBICITY; IMMUNOSUPPRESSIVE TREATMENT; MEMBRANE BINDING; MITOCHONDRIAL MEMBRANE; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; RAT; SPECIES DIFFERENCE; STOICHIOMETRY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; HUMANS; KINETICS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; RATS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0034823624     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.02061.x     Document Type: Article

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