Dissection of the effects of tumor necrosis factor-α and class II gene polymorphisms within the MHC on murine systemic lupus erythematosus (SLE)

International Immunology

Volumn 10, Issue 10, 1998, Pages 1467-1472

  Fujimura, Tomoyuki ^a,b   Hirose, Sachiko ^a,c   Jiang, Yi ^a   Kodera, Sanki ^a,d   Ohmuro, Hiroyuki ^d   Zhang, Danqing ^a   Hamano, Yoshitomo ^a   Ishida, Hiroshi ^e   Furukawa, Susumu ^b   Shirai, Toshikazu ^a,c  

^a JUNTENDO UNIVERSITY   (Japan)

^b YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e UTANO NATIONAL HOSPITAL   (Japan)

Author keywords

Gene polymorphism; H 2 congenic mice; MHC class II; New Zealand mice; Systemic lupus erythematosus; Tumor necrosis factor

Indexed keywords

DNA ANTIBODY; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; DNA POLYMORPHISM; DOWN REGULATION; FEMALE; GENETIC PREDISPOSITION; HAPLOTYPE; HISTOPATHOLOGY; LUPUS ERYTHEMATOSUS NEPHRITIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; FEMALE; GENES, MHC CLASS II; LUPUS ERYTHEMATOSUS, SYSTEMIC; MACROPHAGES, PERITONEAL; MICE; MICE, CONGENIC; MICE, INBRED BALB C; MICE, INBRED NZB; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); TUMOR NECROSIS FACTOR-ALPHA;

EID: 7344261878     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/10.10.1467     Document Type: Article

References (33)

1. 1 hybrid mice. Eur. J. Immunol. 16:1631.
2. Hirose, S., Kinoshita, K., Nozawa, S., Nishimura, H. and Shirai, T. 1990. Effects of major histocompatibility complex on autoimmune disease of H-2-congenic New Zealand mice. Int. Immunol. 2:1091.
3. 1 mice detected by T cell clones. J. Immunol. 150:4777.
4. + T-cell clones. Immunology 83:221.
5. Jacob, C. O. and McDevitt, H. C. 1988. Tumor necrosis factor-α in murine autoimmune 'lupus' nephritis. Nature 331:356.
6. Jongeneel, C. V., Acha-Orbea, H. and Blankenstein, T. 1990. A polymorphic microsatellite in the tumor necrosis factor α promoter identifies an allele unique to the NZW mouse strain. J. Exp. Med. 171:2141.
7. Jacob, C. O., Hwang, F., Lewis, G. D. and Stall, A. M. 1991. Tumor necrosis factor alpha in murine systemic lupus erythematosus disease model: implications for genetic predisposition and immune regulation. Cytokine 3:551.
8. Müller, U., Jongeneel, C. V., Nedospasov, S. A., Lindahl, K. F. and Steinmetz, M. 1987. Tumor necrosis factor and lymphotoxin genes map close to H-2D in the mouse major histocompatibility complex. Nature 325:265.
9. Jacob, C. O., Lee, S. K. and Strassmann, G. 1996. Mutational analysis of TNF-α gene reveals a regulatory role for the 3′-untranslated region in the genetic predisposition to lupus-like autoimmune disease. J. Immunol. 156:3043.
10. Brennan, D. C., Yui, M. A., Wuthrich, R. P. and Kelley, V. E. 1989. Tumor necrosis factor and IL-1 in New Zealand black/white mice. Enhanced gene expression and acceleration of renal injury. J. Immunol. 143:3470.
11. 1 mice. Int. Immunol. 6:1857.
12. Hogan, M. M. and Vogel, S. N. 1991. Measurement of tumor necrosis factor α and β. In Coligan, J. E., Kruisbeek, A. M., Margulies, D. H.,Shevach, E. M. and Strober, W., eds, Current Protocols in Immunology, p. 6.10.1. John Wiley & Sons, New York.
13. Klein, J., Figueroa, F. and David, C. S. 1983. H-2 haplotypes, genes and antigens, second listing. II. The H-2 complex. Immunogenetics 17:553.
14. Klein, J. 1975. The S region and miscellaneous H-2-associated loci. In Biology of the Mouse Histocompatibility-2 Complex, p. 493. Springer-Verlag, Berlin.
15. Klein, J., Flaherty, L., VandeBerg, J. L. and Shreffler, D. C. 1978. H-2 haplotypes, genes, regions, and antigens: first listing. Immunogenetics 6:489.
16. Figueroa, F., Tewarson, S., Neufeld, E. and Klein, J. 1982. H-2 haplotypes of strains DBR7, B10.NZW, NFS, BO2, STU, T01, and TO2. Immunogenetics 15:431.
17. 1 mice. Immunogenetics 32: 63.
18. u of B10.PL mice. Immunogenetics 33:413.
19. Liu, J., Marino, M, W., Wong, G., Grail, D., Dunn, A., Bettadapora, J., Slavin, A. J., Old, L. and Bernard, C. C. A. 1998. TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination, Nature Med. 4:78.
20. Grewal, I. S., Grewal, K. D., Wong, F. S., Picarella, D. E., Janeway, C. A. and Flavell, R. A. 1996. Local expression of transgene encoded TNF-α in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells. J. Exp. Med. 184:1963,
21. McSorley, S. J., Soldera, S., Malherbe, L., Carnaud, C., Locksley, R. M., Flavell, R. A. and Glaichenhaus, N. 1997. Immunological tolerance to a pancreatic antigen as a result of local expression of TNFα by islet β cells. Immunity 7:401.
22. Horwitz, D. A., Gray, J. D., Ohtsuka, K., Hirokawa, M. and Takahashi, T. 1997. The immunoregulatory effects of NK cells: the role of TGF-β and implications for autoimmunity. Immunol. Today 18:538.
23. Ohtsuka, K., Gray, J. D., Stimmler, M. and Horwitz, D. A. 1996. Production of transforming growth factor β1 by lymphocytes in human systemic lupus erythematosus. Arthritis Rheum. 39:S251.
24. Maini, R. N., Elliott, M. J., Brennan, F. M., Williams, R. O., Chu, C. Q., Paleolog, E., Charles, P. J., Taylor, P. C. and Feldmann, M. 1995. Monoclonal anti-TNFα antibody as a probe of pathogenesis and therapy of rheumatoid disease. Immunol. Rev. 144:195.
25. Yang, X. D., Tish, R., Singer, S. M., Cao, Z. A., Liblau, R. S., Shreiber, R. D. and McDevitt, H. O. 1994. Effect of tumor necrosis factor α on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process. J. Exp. Med. 180:995.
26. Satoh, J., Seino, H., Abo, T., Tanaka, S.-I., Shintani, S., Ohta, S., Tamura, K., Sawai, T., Nobunaga, T., Oteki, T., Kumagai, K. and Toyota, T. 1989. Recombinant human tumor necrosis factor-α suppresses autoimmune diabetes in nonobese diabetic mice. J. Clin. Invest. 84:1345.
27. Jacob, C. O., Aiso, S., Michie, S. A., McDevitt, H. O. and Acha-Orbea, H. 1990. Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-α and interleukin-1. Proc. Natl Acad. Sci. USA 87:968.
28. Bazzoni, F. and Beutler, B. 1995. Comparative expression of TNF-α alleles from normal and autoimmune-prone MHC haplotypes. J. Inflamm. 45:106.
29. z on autoimmune disease in New Zealand mice. Int. Immunol. 8:967.
30. Nygard, N. R., McCarthy, D. M., Schiffenbauer, J. and Schwartz, B. D. 1993. Mixed haplotypes and autoimmunity. Immunol. Today 14:53.
31. 1 mice. Immunogenetics 40:150.
32. 1 mice with monoclonal antibody to L3T4. J. Exp. Med. 161:378.
33. 1 hybrid. J. Immunol. 136:1247.