Control of Mycobacterium tuberculosis through mammalian Toll-like receptors

Current Opinion in Immunology

Volumn 14, Issue 4, 2002, Pages 452-457

  Stenger, Steffen ^a   Modlin, Robert L ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; INTERLEUKIN 12; LIPOARABINOMANNAN; LIPOPROTEIN; MESSENGER RNA; MYCOBACTERIUM ANTIGEN; NITRIC OXIDE SYNTHASE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; BACTERIAL ANTIGEN; CELL SURFACE RECEPTOR; DROSOPHILA PROTEIN; MEMBRANE PROTEIN; REACTIVE NITROGEN SPECIES;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; APOPTOSIS; CELL MATURATION; CYTOKINE RELEASE; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; INFECTION CONTROL; MYCOBACTERIOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; REVIEW; T LYMPHOCYTE ACTIVATION; TH1 CELL; ANIMAL; ANTIGEN PRESENTATION; BIOLOGICAL MODEL; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE; MOUSE MUTANT; MUTATION; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; TUBERCULOSIS;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, BACTERIAL; APOPTOSIS; DENDRITIC CELLS; DROSOPHILA PROTEINS; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MODELS, IMMUNOLOGICAL; MUTATION; MYCOBACTERIUM TUBERCULOSIS; REACTIVE NITROGEN SPECIES; RECEPTORS, CELL SURFACE; TH1 CELLS; TOLL-LIKE RECEPTORS; TUBERCULOSIS;

EID: 0036668241     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(02)00355-2     Document Type: Review

References (46)

1. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
2. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
3. Toll-like receptors: Key mediators of microbe detection
4. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
5. Toll-like receptors: Critical proteins linking innate and acquired immunity
6. Nucleotide sequence of the 19 kDa antigen gene from Mycobacterium tuberculosis
7. Host defense mechanisms triggered by microbial lipoproteins through Toll-like receptors
8. Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by Toll-like receptor 2
9. Preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a Toll-like receptor 2- and MyD88-dependent signaling pathway
10. Cell activation and apoptosis by bacterial lipoproteins through Toll-like receptor-2
11. Bacterial lipopolysaccharide activates NF-κB through Toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells
12. Lipoarabinomannan from Mycobacterium tuberculosis induces the production of tumour necrosis factor from human and murine macrophages
13. The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors
14. Different Toll-like receptor agonists induce distinct macrophage responses
15. Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: Role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling
16. Discrimination of bacterial lipoproteins by Toll-like receptor 6
17. Human Toll-like receptors mediate cellular activation by Mycobacterium tuberculosis
18. Toll-like receptor-2 mediates Mycobacteria-induced proinflammatory signaling in macrophages
19. Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses
20. Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products
21. Intracellular trafficking in Mycobacterium tuberculosis and Mycobacterium avium-infected macrophages
22. Regulation of Toll-like receptor 2 expression by macrophages following Mycobacterium avium infection
23. NFκB and Sp1 elements are necessary for maximal transcription of Toll-like receptor 2 induced by Mycobacterium avium
24. Differential expression and regulation of Toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
25. Activation of human dendritic cells following infection with Mycobacterium tuberculosis
26. Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2
27. Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: Involvement of Toll-like receptors
28. Mycobacterium tuberculosis inhibits MHC class II antigen processing in murine bone marrow macrophages
29. Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosis
30. Mycobacterium tuberculosis 19-kilodalton lipoprotein inhibits Mycobacterium smegmatis-induced cytokine production by human macrophages in vitro
31. The 19-kD antigen and protective immunity in a murine model of tuberculosis
32. Human macrophage activation programs induced by bacterial pathogens
33. Mannosylated lipoarabinomannans inhibit IL-12 production by human dendritic cells: Evidence for a negative signal delivered through the mannose receptor
34. Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells
35. Activation of Toll-like receptor 2 on human dendritic cells triggers induction of IL-12, but not IL-10
36. Toll-like receptors control activation of adaptive immune responses
37. Nitric oxide and the immune response
38. Induction of direct antimicrobial activity through mammalian Toll-like receptors
39. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
40. Genetic control of susceptibility to Salmonella typhimurium in mice: Role of the LPS gene
41. Toll-like receptor 4 mediates innate immune responses to Haemophilus influenzae infection in mouse lung
42. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
43. TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection
44. Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi
45. Gamma interferon-producing CD4+ T lymphocytes in the lung correlate with resistance to infection with Mycobacterium tuberculosis
46. Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients