Carcinogenicity testing of IL-10: Principles and practicalities

Human and Experimental Toxicology

Volumn 21, Issue 7, 2002, Pages 347-358

  Rosenblum, I Y ^a   Dayan, A D ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

Carcinogenicity testing; Cytokine; Experimental models; Immune modulator; rhuIL 10; Toxicity testing regulations

Indexed keywords

RECOMBINANT INTERLEUKIN 10; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CARCINOGEN TESTING; CELL LINE; CONTROLLED STUDY; DRUG CARCINOGENICITY; FEASIBILITY STUDY; HUMAN; HUMAN CELL; IMMUNE SYSTEM; IMMUNOGENICITY; MOUSE; NONHUMAN; PATHOLOGY; PRIORITY JOURNAL; RISK ASSESSMENT; SPECIES DIFFERENCE; TOXICITY TESTING; TRANSGENIC MOUSE; TUMOR BIOPSY; TUMOR CELL;

ANIMALS; CARCINOGENICITY TESTS; HUMANS; INTERLEUKIN-10; RECOMBINANT PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; MUS MUSCULUS; RODENTIA;

EID: 0036656377     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/0960327102ht275oa     Document Type: Article

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