Quantitative immunohistochemical analysis of cytokine profiles in Epstein-Barr virus-positive and -negative cases of Hodgkin's disease

Journal of Pathology

Volumn 190, Issue 2, 2000, Pages 143-149

  Dukers, D F ^a   Jaspars, L H ^a   Vos, W ^a   Oudejans, J J ^a   Hayes, D ^a   Cillessen, S ^a   Middeldorp, J M ^a,b   Meijer, C J L M ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Organon Teknika   (Netherlands)

Author keywords

Cytokines; EBV; Hodgkin's disease; Immunohistochemistry; Interleukin 10

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; LATENT MEMBRANE PROTEIN 1;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; EPSTEIN BARR VIRUS; HODGKIN DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOMODULATION; IMMUNOSURVEILLANCE; LYMPHOPROLIFERATIVE DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REED STERNBERG CELL;

EID: 0033952886     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(200002)190:2<143::AID-PATH519>3.0.CO;2-5     Document Type: Article

References (42)

1. Diehl V, von Kalle C, Fonatsch C, Tesch H, Juecker M, Schaadt M. The cell of origin in Hodgkin's disease. Semin Oncol 1990; 17: 660-672.
2. Klein G. In The Epstein-Barr Virus, Epstein MA, Achong BG (eds). Springer-Verlag: Berlin, 1979; 339.
3. Weiss LM, Movahed LA, Warnke RA, Sklar J. Detection of Epstein-Barr viral genomes in Reed-Sternberg cells of Hodgkin's disease. N Engl J Med 1989; 320: 502-506.
4. Weiss LM, Strickler JG, Warnke RA, Purtilo DT, Sklar J. Epstein-Barr viral DNA in tissues of Hodgkin's disease. Am J Pathol 1987; 129: 86-91.
5. Libetta CM, Pringle JH, Angel CA, Craft AW, Malcolm AJ, Lauder I. Demonstration of Epstein Barr viral DNA in formalin fixed, paraffin embedded samples of Hodgkin's disease. J Pathol 1990; 161: 255-260.
6. Thorley-Lawson DA, Israelsohn ES. Generation of specific cytotoxic T cells with a fragment of the Epstein-Barr virus-encoded p63/latent membrane protein. Proc Natl Acad Sci USA 1987; 84: 5384-5388.
7. Khanna R, Burrows SR, Nicholls J, Poulsen LM. Identification of cytotoxic T cell epitopes within Epstein-Barr virus (EBV) oncogene latent membrane protein 1 (LMP1): evidence for HLA A2 supertype-restricted immune recognition of EBV-infected cells by LMP1-specific cytotoxic T lymphocytes. Eur J Imunol 1998; 28: 451-458.
8. Rickinson AB, Moss DJ, Allen DJ, Wallace LE, Rowe M, Epstein MA. Reactivation of Epstein-Barr virus specific cytotoxic T cells by in vitro stimulation with the autologous lymphoblastoid cell line. Int J Cancer 1981; 27: 593-601.
9. Oudejans JJ, Jiwa NM, Kummer JA, et al. Analysis of major histocompatibility complex class 1 expression on Reed-Sternberg cells in relation to the cytotoxic T-cell response in Epstein-Barr virus positive and negative Hodgkin's disease. Blood 1996; 87: 3844-3851.
10. Oudejans JJ, Jiwa NM, Kummer JA, et al. Activated cytotoxic T cells as prognostic marker in Hodgkin's disease. Blood 1997; 89: 1376-1382.
11. Frisan T, Sjoberg J, Dolcetti R, et al. Local suppression of Epstein-Barr virus (EBV)-specific cytotoxicity in biopsies of EBV-positive Hodgkin's disease. Blood 1995; 89: 1493-1501.
12. de Waal Malefyt R, Yssel H, Roncarolo MG, Spits H, de Vries JE. Interleukin 10. Curr Opin Immunol 1992; 4: 314-320.
13. Chouaib S, Asselin-Paturel C, Mami-Chouaib F, Caignard A, Blay JY. The host-tumor immune conflict: from immunosuppression to resistance and destruction. Immunol Today 1997; 18: 493-497.
14. Matsuda M, Salazar F, Petersson M, et al. Interleukin 10 pretreatment protects target cells from tumor-and allo-specific cytotoxic T cells and downregulates HLA class I expression. J Exp Med 1994; 180: 2371-2376.
15. Becker JC, Czerny C, Brocker EB. Maintenance of clonal anergy by endogenously produced IL-10. Int Immunol 1994; 6: 1605-1612.
16. Fontana A, Frei K, Bodmer S, et al. Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice. J Immunol 1989; 143: 3230-3234.
17. Fitzpatrick L, Makrigiannis AP, Kaiser M, Hoskin DW. Anti-CD3-activated killer T cells: interferon-gamma and interleukin-10 cross-regulate granzyme B expression and the induction of major histocompatibility complex-unrestricted cytotoxicity. J Interferon Cytokine Res 1996; 16: 537-546.
18. Ding L, Shevach EM. IL-10 inhibits mitogen-induced T cell proliferation by selectively inhibiting macrophage costimulatory function. J Immunol 1992; 148: 3133-3139.
19. Nakagomi H, Dolcetti R, Bejarano MT, Pisa P, Kiessling R, Masucci MG. The Epstein-Barr virus latent membrane protein 1 (LMP1) induces interleukin 10 production in Burkitt lymphoma lines. Int J Cancer 1994; 57: 240-244.
20. Hsu DH, de Waal-Malefyt R, Fiorentino DF, et al. Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1. Science 1990; 250: 830-832.
21. de Waal Malefyt R, Haanen J, Spits H, et al. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via down regulation of class II major histocompatibility complex expression. J Exp Med 1991; 174: 915-924.
22. Herbst H, Foss HD, Samol J, et al. Frequent expression of interleukin-10 by Epstein Barr virus-harboring tumor cells of Hodgkin's disease. Blood 1996; 87: 2918-2929.
23. Ohshima K, Suzumiya J, Akamatu M, Takeshita M, Kikuchi M. Human and viral interleukin-10 in Hodgkin's disease, and its influence on CD4+ and CD8+ T lymphocytes. Int J Cancer 1995; 62: 5-10.
24. Lukes RJ, Craver LF, Hall TC, Rappaport H, Ruben P. Report of the Nomenclature Committee. Cancer Res 1966; 26: 1311.
25. Jiwa NM, Kanavaros P, De Bruin PC, et al. Presence of Epstein-Barr virus harbouring small and intermediate-sized cells in Hodgkin's disease: is there a relationship with Reed Sternberg cells? J Pathol 1993; 170: 129-136.
26. Lee CLY, Lee SHS, Jay FT, Rozee KR. Immunobiological study of interferon-gamma-producing cells after staphylococcal enterotoxin B stimulation. Immunology 1990; 70: 94-99.
27. Kummer JA, Kamp AM, van Katwijk M, et al. Production and characterization of monoclonal antibodies raised against recombinant human granzymes A and B showing cross reactions with the natural proteins. J Immunol Methods 1993; 163: 77-83.
28. Oudejans JJ, Kummer JA, Jiwa M, et al. Granzyme B expression in Reed Sternberg cells of Hodgkin's disease. Am J Pathol 1996; 148: 233-240.
29. Andersson J, Abrams J, Bjork L, et al. Concomitant in vivo production of 19 different cytokines in human tonsils. Immunology 1994; 83: 16-24.
30. Bobrow MN, Harris TD, Shaughnessy KJ, Litt GJ. Catalyzed reporter deposition, a novel method of signal amplification. I. Application to immunoassays. J Immunol Methods 1989; 125: 279-285.
31. Bobrow MN, Shaughnessy KJ, Litt GJ. Catalyzed reporter deposition, a novel method of signal amplification. II. Application to membrane immunoassays. J Immunol Methods 1991; 137: 103-112.
32. Brink AATP, Oudejans JJ, Jiwa NM, Walboomers JMM, Meijer CJLM, van den Brule AJC. Multiprimed cDNA synthesis followed by PCR is the most suitable method for Epstein Barr virus transcript analysis in small lymphoma biopsies. Mol Cell Probes 1997; 11: 39-47.
33. Compton J. Nucleic acid sequence-based amplification. Nature 1991; 350: 91-92.
34. Kievits T, van Gemen B, van Strijp D, et al. NASBA isothermal enzymatic in vitro nucleic acid amplification optimized for the diagnosis of HIV-1 infection. J Virol Methods 1991; 35: 273-286.
35. Hayes DP, Brink AATP, Vervoort MBHJ, et al. Expression of Epstein-Barr virus (EBV) transcripts encoding homologues to important human proteins in diverse EBV associated diseases. Mol Pathol 1999; 52: 97-103.
36. Fleege JC, van Diest PJ, Baak JPA. Computer assisted efficiency testing of different sampling methods for selective nuclear graphic tablet morphometry. Lab Invest 1990; 63: 270-275.
37. Lee SP, Constandinou Thomas WA, Croom-Carter D, et al. Antigen presenting phenotype of Hodgkin Reed-Sternberg cells-analysis of the HLA class I processing pathway and the effects of interleukin-10 on Epstein-Barr virus-specific cytotoxic T-cell recognition. Blood 1998; 92: 1020-1030.
38. Murray PG, Constandinou CM, Crocker J, Young LS, Ambinder RF. Analysis of major histocompatibility complex class I, TAP expression, and LMP2 epitope sequence in Epstein-Barr virus-positive Hodgkin's disease. Blood 1998; 92: 2477-2483.
39. Kanno H, Naka N, Yasunaga Y, et al. Production of the immunosuppressive cytokine interleukin-10 by Epstein-Barr-virus-expressing pyothorax-associated lymphoma: possible role in the development of overt lymphoma in immunocompetent hosts. Am J Pathol 1997; 150: 349-357.
40. Gastl GA, Abrams JS, Nanus DM, et al. Interleukin-10 production by human carcinoma cell lines and its relationship to interleukin-6 expression. Int J Cancer 1993; 55: 96-101.
41. Ho ASY, Moore KW. Interleukin-10 and its receptor. Ther Immunol 1994; 1: 173-185.
42. Howard M, O'Garra A. Biological properties of interleukin 10. Immunol Today 1992; 13: 198-200.