Human liver-derived cells stably modified for regulated proinsulin secretion function as bioimplants in vivo

Journal of Gene Medicine

Volumn 4, Issue 4, 2002, Pages 447-458

  Chen, Xiang ^a,b   Patil, Jawahar G ^a,b,c   Lok, Serene H L ^a,b   Kon, Oi Lian ^a,b  

^a DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c CSIRO   (Australia)

Author keywords

Diabetes; Glucose inducible; Hepatocyte; Zinc inducible

Indexed keywords

CARBOHYDRATE; COMPLEMENTARY DNA; GLUCOKINASE; GLUCOSE; GLUCOSE TRANSPORTER 2; PROINSULIN; ZINC;

ANIMAL EXPERIMENT; ARTICLE; CELL BASED GENE THERAPY; CELL CLONE; CONTROLLED STUDY; DIABETES MELLITUS; DNA RESPONSIVE ELEMENT; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; LIVER CELL; MALE; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; RADIOIMMUNOASSAY; SCID MOUSE; ANIMAL; BIOPROSTHESIS; CELL CULTURE; GENETICS; LIVER; METABOLISM; METHODOLOGY; SECRETION; TISSUE TRANSPLANTATION;

ANIMALS; BIOPROSTHESIS; CELLS, CULTURED; GLUCOSE; HUMANS; LIVER; MICE; PROINSULIN; PROMOTER REGIONS (GENETICS); TISSUE TRANSPLANTATION; TRANSFECTION; ZINC;

EID: 0036633140     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.263     Document Type: Article

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