Flagellin perception: A paradigm for innate immunity

Trends in Plant Science

Volumn 7, Issue 6, 2002, Pages 251-256

  Gómez Gómez, Lourdes ^a,b   Boller, Thomas ^b,c  

^a IDR ^*  (Spain)

^b FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; ARABIDOPSIS; BACTERIA (MICROORGANISMS); MAMMALIA;

ARABIDOPSIS PROTEIN; CELL SURFACE RECEPTOR; DROSOPHILA PROTEIN; FLAGELLIN; FLS2 PROTEIN, ARABIDOPSIS; MEMBRANE PROTEIN; PROTEIN KINASE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 5;

ANIMAL; BACTERIUM; BIOLOGICAL MODEL; FUNGUS; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MICROBIOLOGY; MOLECULAR EVOLUTION; PHYSIOLOGY; PLANT; PLANT DISEASE; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ARABIDOPSIS PROTEINS; BACTERIA; DROSOPHILA PROTEINS; EVOLUTION, MOLECULAR; FLAGELLIN; FUNGI; IMMUNITY, NATURAL; MEMBRANE GLYCOPROTEINS; MODELS, BIOLOGICAL; PLANT DISEASES; PLANTS; PROTEIN KINASES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 5; TOLL-LIKE RECEPTORS;

EID: 0036618235     PISSN: 13601385     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1360-1385(02)02261-6     Document Type: Review

References (61)

1. Yang, Y.O. et al. (1997) Signal perception and transduction in defense responses. Genes Dev. 11, 1621-1639
2. Dangl, J.L. and Jones, J.D.G. (2001) Plant pathogens and integrated defence responses to infection. Nature 411, 826-833
3. Nürnberger, T. and Scheel, D. (2001) Signal transmission in the plant immune response. Trends Plant Sci. 6, 372-379
4. Ellis, J. et al. (2000) Structure, function, and evolution of plant disease resistance genes. Curr. Opin. Plant Biol. 3, 278-284
5. Cohn, J. et al. (2001) Innate immunity in plants. Curr. Opin. Immunol. 13, 55-62
6. Fluhr, R. (2001) Sentinels of disease. Plant resistance genes. Plant Physiol. 127, 1367-1374
7. Boller, T. (1995) Chemoperception of microbial signals in plant cells. Annu. Rev. Plant Physiol. Plant Mol. Biol. 46, 189-214
8. Ebel, J. and Mithöfer, A. (1998) Early events in the elicitation of plant defence. Planta 206, 335-348
9. Felix, G. et al. (1993) Specific perception of subnanomolar concentrations of chitin fragments by tomato cells: induction of extracellular alkalinization, changes in protein phosphorylation, and establishment of a refractory state. Plant J. 4, 307-316
10. Granado, J. et al. (1995) Perception of fungal sterols in plants. Subnanomolar concentrations of ergosterol elicit extracellular alkalinization in tomato cells. Plant Physiol. 107, 485-490
11. Hoffmann, J.A. and Reichhart, J-M. (2002) Drosophila innate immunity: an evolutionary perspective. Nat. Immunol. 3, 121-126
12. Kimbrell, D.A. and Beutler, B. (2001) The evolution and genetics of innate immunity. Nat. Rev. Genet. 2, 256-267
13. Kopp, E.B. and Medzhitov, R. (1999) The Toll-receptor family and control of innate immunity. Curr. Opin. Immunol. 11, 13-18
14. Medzhitov, R. and Janeway, C.A.J. (2000) Innate immune recognition: mechanisms and pathways. Immunol. Rev. 173, 89-97
15. Silverman, N. and Maniatis, T. (2001) NF-κB signaling pathways in mammalian and insect innate immunity. Genes Dev. 15, 2321-2342
16. Underhill, D.M. and Ozinsky, A. (2002) Toll-like receptors: key mediators of microbe detection. Curr. Opin. Immunol. 14, 103-110
17. Moens, S. and Vanderleyden, J. (1996) Functions of bacterial flagella. Crit. Rev. Microbiol. 22, 67-100
18. Samatey, F.A. et al. (2001) Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling. Nature 410, 331-337
19. Komoriya, K. et al. (1999) Flagellar proteins and type III-exported virulence factors are the predominant proteins secreted into the culture media of Salmonella typhimurium. Mol. Microbiol. 34, 767-779
20. Finlay, B.B. and Falkow, S. (1997) Common themes in microbial pathogenicity revisited. Microbiol. Mol. Biol. Rev. 61, 136-169
21. Tans-Kersten, J. et al. (2001) Ralstonia solanacearum needs motility for invasive virulence on tomato. J. Bacteriol. 183, 3597-3605
22. Lemaitre, B. et al. (1997) Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc. Natl. Acad. Sci. U. S. A. 94, 14614-14619
23. McDermott, P.F. et al. (2000) High-affinity interaction between Gram-negative flagellin and a cell surface polypeptide results in human monocyte activation. Infect. Immun. 68, 5525-5529
24. Eaves-Pyles, T. et al. (2001) Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: IκBα degradation, induction of aitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction. J. Immunol. 166, 1248-1260
25. Sierro, F. et al. (2001) Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 98, 13722-13727
26. Felix, G. et al. (1999) Plants recognize bacteria through the most conserved domain of flagellin. Plant J. 18, 265-276
27. Gómez-Gómez, L. et al. (1999) A single dominant gene determines sensitivity to bacterial flagellin in Arab idopsis thaliana. Plant J. 18, 277-284
28. Asai, T. et al. (2002) MAP kinase signalling cascade in Arabidopsis innate immunity. Nature 415, 977-983
29. Che, F.S. et al. (2000) Flagellin from an incompatible strain of Pseudomonas avenae induces a resistance response in cultured rice cells. J. Biol. Chem. 275, 32347-32356
30. Gómez-Gómez, L. and Boller, T. (2000) FLS2: an LRR receptor-like kinase involved in the perception of the bacterial elicitor flagellin in Arabidopsis. Mol. Cell 5, 1003-1011
31. Buell, C.R. and Somerville, S.C. (1997) Use of Arabidopsis recombinant inbred lines reveals a monogenic and a novel digenic resistance mechanism to Xanthomonas campestris pv campest ris. Plant J. 12, 21-29
32. Deslandes, L. et al. (1998) Genetic characterization of RRS1, a recessive locus in Arabidopsis thaliana that confers resistance to the bacterial soilborne pathogen Ralstonia solanacearum. Mol. Plant-Microbe Interact. 11, 659-667
33. Shiu, S-H. and Bleecker, A.B. (2001) Receptor-like kinases from Arabidopsis form a monophyletic gene family related to animal receptor kinases. Proc. Natl. Acad. Sci. U. S. A. 98, 10763-10768
34. Kobe, B. and Deisenhofer, J. (1995) A structural basis of the interactions between leucine-rich repeats and protein ligands. Nature 374, 183-186
35. Song, W.Y. et al. (1995) A receptor kinase-like protein encoded by the rice disease resistance gene, Xa21. Science 270, 1804-1806
36. Torii, K.U. (2000) Receptor kinase activation and signal transduction in plants: an emerging picture. Curr. Opin. Plant Biol. 3, 361-367
37. Clark, S.E. et al. (1997) The CLAVATA1 gene encodes a putative receptor kinase that controls shoot and floral meristem size in Arabidopsis. Cell 89, 575-585
38. Jeong, S. et al. (1999) The Arabidopsis CLAVATA2 gene encodes a receptor-like protein required for the stability of the CLAVATA1 receptor-like kinase. Plant Cell 11, 1925-1933
39. Trotochaud, A.E. et al. (2000) CLAVATA3, a multimeric ligand for the CLAVATA1 receptor-kinase. Science 289, 613-617
40. Meindl, T. et al. (2000) The bacterial elicitor flagellin activates its receptor in tomato cells according to the address-message concept. Plant Cell 12, 1783-1794
41. Bauer, Z. et al. (2001) Sensitivity of different ecotypes and mutants of Arabidopsis thaliana towards the bacterial elicitor flagellin correlates with the presence of receptor binding sites. J. Biol. Chem. 276, 45669-45676
42. Tzou, P. et al. (2002) How Drosophila combats microbial infection: a model to study innate immunity and host-pathogen interactions. Curr. Opin. Microbiol. 5, 102-110
43. Imler, J-L. and Hoffmann, J.A. (2001) Toll receptors in innate immunity. Trends Cell Biol. 11, 304-311
44. Sieling, P.A. and Modlin, R.L. (2002) Toll-like receptors: mammalian 'taste receptors' for a smorgasbord of microbial invaders. Curr. Opin. Microbiol. 5, 70-75
45. Aderem, A. and Ulevitch, R.J. (2000) Toll-like receptors in the induction of the innate immune response. Nature 406, 782-787
46. Akira, S. et al. (2001) Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2, 675-680
47. Hayashi, F. et al. (2001) The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410, 1099-1103
48. Eaves-Pyles, T. et al. (2001) Salmonella flagellin-dependent proinflammatory responses are localized to the conserved amino and carboxyl regions of the protein. J. Immunol. 167, 7009-7016
49. Cao, H. et al. (1997) The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats. Cell 88, 57-63
50. Thomma, B.P.H.J. et al. (2001) The complexity of disease signalingin Arabidopsis. Curr. Opin. Immunol. 13, 63-68
51. Peck, S.C. et al. (2001) Directed proteomics identifies a plant-specific protein rapidly phosphorylated in response to bacterial and fungal elicitors. Plant Cell 13, 1467-1475
52. Ligterink, W. and Hirt, H. (2001) Mitogen-activated protein (MAP) kinase pathways in plants: versatile signaling tools. Int. Rev. Cytol. 201, 209-275
53. Nühse, T.S. et al. (2000) Microbial elicitors induce activation and dual phosphorylation of the Arabidopsis thaliana MAPK 6. J. Biol. Chem. 275, 7521-7526
54. Cardinale, F. et al. (2000) Differential activation of four specific MAPK pathways by distinct elicitors. J. Biol. Chem. 275, 36734-36740
55. Desikan, R. et al. (2001) Harpin induces activation of the Arabidopsis mitogen-activated protein kinases AtMPK4 and AtMPK6. Plant Physiol. 126, 1579-1587
56. Romeis, T. (2001) Protein kinases in the plant defence response. Curr. Opin. Plant Biol. 4, 407-414
57. Eulgem, T. et al. (2000) The WRKY superfamily of plant transcription factors. Trends Plant Sci. 5, 199-206
58. Williams, R.W. et al. (1997) A possible role for kinase-associated protein phosphatase in the Arabidopsis CLAVATA1 signaling pathway. Proc. Natl. Acad. Sci. U. S. A. 94, 10467-10472
59. Gómez-Gómez, L. et al. (2001) Both the extracellular leucine-rich repeat domain and the kinase activity of FLS2 are required for flagellin binding and signaling in Arabidopsis. Plant Cell 13, 1155-1163
60. Brown, P. (2001) Cinderella goes to the ball. Nature 410, 1018-1020
61. Staskawicz, B.J. et al. (2001) Common and contrasting themes of plant and animal diseases. Science 292, 2285-2289