Macrophages resistant to endogenously generated nitric oxide-mediated apoptosis are hypersensitive to exogenously added nitric oxide donors: Dichotomous apoptotic response independent of caspase 3 and reversal by the mitogen-activated protein kinase kinase (MEK) inhibitor PD 098059

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 9, 1998, Pages 5045-5050

  Mohr, Susanne ^a   Mccormick, Thomas S ^a   Lapetina, Eduardo G ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CASPASE 3; CYCLIN KINASE INHIBITOR; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE DONOR; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL CYCLE G2 PHASE; ENZYME INHIBITION; ENZYME REGULATION; HYPERSENSITIVITY; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CASPASE 3; CASPASES; CELL CYCLE; CELL LINE; CYSTEINE ENDOPEPTIDASES; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; GLUTATHIONE; MACROPHAGES; MAP KINASE KINASE 1; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NITRIC OXIDE; NITROSO COMPOUNDS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTEINS; S-NITROSOGLUTATHIONE;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 0032574692     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.9.5045     Document Type: Article

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