Cutting edge: Differential segregation of the Src homology 2-containing protein tyrosine phosphatase-1 within the early NK cell immune synapse distinguishes noncytolytic from cytolytic interactions

Journal of Immunology

Volumn 168, Issue 7, 2002, Pages 3150-3154

  Vyas, Yatin M ^a   Maniar, Hina ^a   Dupont, Bo ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN KINASE C; PROTEIN TYROSINE PHOSPHATASE; TALIN;

ARTICLE; CELL INTERACTION; CYTOLYSIS; CYTOTOXICITY; HUMAN; HUMAN CELL; NATURAL KILLER CELL; NORMAL HUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN INTERACTION; QUANTITATIVE ASSAY; SRC HOMOLOGY DOMAIN; SYNAPSE;

EID: 0036533576     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.7.3150     Document Type: Article

References (23)

1. In search of the "missing self": MHC molecules and NK cell recognition
2. NK cell receptors
3. Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor
4. Sequential involvement of Lck and SHP-1 with MHC-recognizing receptors on NK cells inhibits FcR-initiated tyrosine kinase activation
5. Cutting edge: NK cell inhibitory receptors prevent tyrosine phosphorylation of the activation receptor 2B4 (CD244)
6. A receptor/cytoskeletal movement triggered by costimulation during T cell activation
7. The immunological synapse: A molecular machine controlling T cell activation
8. Normal and abnormal secretion by haemopoietic cells
9. Three-dimensional segregation of supramolecular activation clusters in T cells
10. The immunological synapse of CTL contains a secretory domain and membrane bridges
11. A balance between positive and negative signals in cytotoxic lymphocytes regulates the polarization of lipid rafts during the development of cell-mediated killing
12. The human natural killer cell immune synapse
13. Ly49A inhibitory receptors redistribute on natural killer cells during target cell interaction
14. Signaling at the inhibitory natural killer cell immune synapse regulates lipid raft polarization but not class I MHC clustering
15. Adhesion to target cells is disrupted by the killer cell inhibitory receptor
16. Spatial organization of signal transduction molecules in the NK cell immune synapses during MHC class I-regulated noncytolytic and cytolytic interactions
17. Live cell fluorescence imaging of T cell MEKK2: Redistribution and activation in response to antigen stimulation of the T cell receptor
18. The talin head domain binds to integrin β subunit cytoplasmic tails and regulates integrin activation
19. Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses
20. SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors
21. Cutting edge: A role for the adaptor protein LAT in human NK cell-mediated cytotoxicity
22. Involvement of SHP-1 tyrosine phosphatase in TCR-mediated signaling pathways in lipid rafts
23. Coupling of the TCR to integrin activation by SLAP-130/Fyb