A balance between positive and negative signals in cytotoxic lymphocytes regulates the polarization of lipid rafts during the development of cell- mediated killing

Journal of Experimental Medicine

Volumn 191, Issue 2, 2000, Pages 347-354

  Lou, Zhenkun ^a   Jevremovic, Dragan ^a   Billadeau, Daniel D ^a   Leibson, Paul J ^a,b  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

Cytotoxicity, immunologic; Natural killer cell; Signal transduction; Tyrosine kinase; Tyrosine phosphatase

Indexed keywords

CELL SURFACE RECEPTOR; CHOLESTEROL; PROTEIN TYROSINE KINASE; SPHINGOLIPID;

ARTICLE; CATALYSIS; CELL ACTIVATION; CELL MEDIATED CYTOTOXICITY; CELL MEMBRANE; CYTOTOXIC LYMPHOCYTE; HUMAN; HUMAN CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN FAMILY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; CHOLESTEROL; CYTOTOXICITY, IMMUNOLOGIC; ENZYME PRECURSORS; HLA-B ANTIGENS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; K562 CELLS; KILLER CELLS, NATURAL; MICE; PROTEIN-TYROSINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, IMMUNOLOGIC; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION; SPHINGOLIPIDS; SRC-FAMILY KINASES; TUMOR CELLS, CULTURED;

EID: 0034677175     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.2.347     Document Type: Article

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