The Roles of CD11/CD18 and ICAM-1 in Acute Pseudomonas aeruginosa-Induced Pneumonia in Mice

Journal of Immunology

Volumn 157, Issue 11, 1996, Pages 5016-5021

  Qin, Lan ^a   Quinlan, William M ^a   Doyle, Nicholas A ^a   Graham, Lori ^a   Sligh, James E ^b   Takei, Fumio ^c   Beaudet, Arthur L ^b   Doerschuk, Claire M ^a,d  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD11 ANTIGEN; CD11B ANTIGEN; CD18 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ACUTE DISEASE; ANIMAL; ARTICLE; BACTERIAL PNEUMONIA; BAGG ALBINO MOUSE; C57BL MOUSE; CELL MOTION; EDEMA; FEMALE; GENETICS; GRAM NEGATIVE INFECTION; IMMUNOLOGY; MOUSE; MOUSE MUTANT; NEUTROPHIL; PHYSIOLOGY; RAT;

ACUTE DISEASE; ANIMALS; ANTIBODIES; ANTIGENS, CD11; ANTIGENS, CD18; CELL MOVEMENT; EDEMA; FEMALE; INTERCELLULAR ADHESION MOLECULE-1; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MACROPHAGE-1 ANTIGEN; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NEUTROPHILS; PNEUMONIA, BACTERIAL; PSEUDOMONAS INFECTIONS; RATS;

EID: 0030459358     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Wisinger, D. 1993. Bacterial pneumonia. Postgrad. Med. 93:43.
2. Meryer, R. G. 1992. Community-acquired pneumonia. J. Hosp. Inf. 22:51.
3. Rodriguez, J. L. 1993. Hospital-acquired Gram-negative pneumonia in critically ill. injured patients. Am. J. Surg. 165:34S.
4. Smith, C. W. 1992. Transendothelial migration. In Adhesion: Its Role in Inflammatory Disease. J. M. Harlan and D. Y. Liu, eds. New York, W. H. Freeman & Co. pp. 83-115.
5. Harlan, J. M., R. K. Winn, N. B. Vedder, C. M. Doerschuk, and C. L. Rice. 1992. In vivo models of leukocyte adherence to endothelium. In Adhesion: Its Role in Inflammatory Disease. J. M. Harlan and D. Y. Liu, eds. New York, W. H. Freeman & Co. pp. 117-150.
6. Doerschuk, C. M., R. K. Winn, H. O. Coxson, and J. M. Harlan. 1990. CD18-dependent and independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits. J. Immunol. 144:2327.
7. 2-integrin CD18 in the local accumulation of neutrophils in pulmonary and cutaneous inflammation in the rabbit. Am. J. Respir. Cell Mol. Biol. 10:391.
8. Kumasaka, T., W. M. Quinlan, N. A. Doyle, L. Graham, and C. M. Doerschuk. 1996. The role of CD11/CD18 in neutrophil emigration during acute recurrent P. aeruginosa-induced pneumonia in rabbits. Am. J. Pathol. 148:1297.
9. Hogg, N. 1991. An integrin overview. Chem. Immunol. 50:1.
10. Smith, C. W., R. Rothlein, B. J. Hughes, M. M. Mariscalo, H. E. Rudloff, F. C. Schmalstieg, and D. C. Anderson. 1988. Recognition of an endothelial determinant for CD18-dependent human neutrophil adherence and transendothelial migration. J. Clin. Invest. 82:1746.
11. Smith, C. W., S. D. Marlin, R. Rothlein, C. Toman, and D. C. Anderson. 1989. Cooperative interactions of LFA-1 and MAC-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro. J. Clin. Invest. 83:2008.
12. Bevilacqua, M. P. 1993. Endothelial-leukocyte adhesion molecules. Ann. Rev. Immunl. 11:767.
13. Albelda, S. M. 1991. Endothelial and epithelial cell adhesion molecules. Am. J. Respir. Cell Mol. Biol. 4:195.
14. Sligh, J. E., C. M. Ballantyne, S. S. Rich, H. K. Hawkins, C. W. Smith, A. Bradley, and A. L. Beaudet. 1993. Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1. Proc. Natl. Acad. Sci. USA 90:8529.
15. Sarmiento, M. N., D. P. Dialynas, D. W. Lancki, K. A. Wall, M. I. Lorber, M. R. Loken, and F. W. Fitch. 1982. Cloned T lymphocytes and monoclonal antibodies as probes for cell surface molecules active in T cell-mediated cytolysis. Immunol. Rev. 68:135.
16. Springer, T., G. Galfre, D. S. Secher, and C. Milstein. 1978. Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur. J. Immunol. 8:539.
17. Takei, F. 1985. Inhibition of mixed lymphocyte response by a rat monoclonal antibody to a novel murine lymphocyte activation antigen (MALA-2). J. Immunol. 134:1403.
18. Horley, K. J., C. Carpenito, B. Baker, and F. Takei. 1989. Molecular cloning of murine intercellular adhesion molecule (ICAM-1). EMBO J. 8:2889.
19. Sanchez-Madrid, F., P. Simon, S, Thompson, and T. A. Springer. 1983. Mapping of antigenic and functional epitopes on the α- and β-subunits of two related mouse glycoproteins involved in cell interactions, LFA-21 and MAC-1. J. Exp. Med. 158:586.
20. Bullard, D. C., L. Qin, I. Lorenzo, W. M. Quinlan, N. A. Doyle, D. Vestweber, C. M. Doerschuk, and A. L. Beaudet. 1995. P-selectin/ICAM-1 double mutant mice show a complete block in peritoneal emigration of neutrophils. J. Clin. Invest. 95.-1782.
21. Wiebke, J. L., W. M. Quinlan, N. A. Doyle, J. E. Sligh, C. W. Smith, and C. M. Doerschuk. 1995. Lymphocyte accumulation during Pseudomonas aeruginosa-induced pneumonia in rodents does not require CD11a and ICAM-1. Am. J. Respir. Cell Mol. Biol. 12:513.
22. Zar, J. H. 1984. Bioastistical Analysis. 2nd Ed. Prentice-Hall, Inc., Englewood Cliffs, NJ, pp. 162-170.
23. Hollard, B. S., and M. D. Copenhaver. 1987. An improved sequentially rejective Bonferroni test procedure. Biometrics 43:417.
24. Albelda, S. M., C. M. Smith, and P. A. Ward. 1994. Adhesion molecules and inflammatory injury. FASEB J. 8:504.
25. Mulligan, M. S., G. P. Wilson, R. F. Todd, C. W. Smith, D. C. Anderson, A. A. Vaporciyan, and P. A. Ward. 1993. Role of β1, β2 integrins and ICAM-1 in lung injury after deposition of IgG and IgA immune complexes. J. Immunol. 150: 2407.
26. Mulligan, M. S., C. W. Smith, D. C. Anderson, R. F. Todd III, M. Miyasaka, T. Tamatani, T. B. Issekutz, and P. A. Ward. 1993. Role of leukocyte adhesion molecules in complement-induced lung injury. J. Immunol. 150:2401.
27. Lo, S. K., G. Van Seventer, S. Levin, and S. Wright. 1989. Two leukocyte receptors (CD11a/CD18 and CD11b/CD18) mediate transient adhesion to endothelium by binding to different ligands. J. Immunol. 143:3325.
28. Tosi, M. F., J. M. Starr, C. W. Smith, A. Hamedani, D. C. Gruenert, and M. D. Infeld. 1992. Induction of ICAM-1 expression on human airway epithelial cells by inflammatory cytokines: effect on neutrophil-epithelial cell adhesion. Am. J. Respir. Cell Mol. Biol. 7:214.
29. Wedmore, C. V., and T. J. Williams. 1981. Control of vascular permeability by polymorphonuclear leukocytes in inflammation. Nature 289:646.
30. King, P. D., E. T. Sandberg, A. Selvakumar, P. Fang, A. L. Beaudet, and B. Dupont. 1995. Novel isoforms of murine intercellular adhesion molecule-1 generated by alternative RNA splicing. J. Immunol. 154:6080.
31. Burns, A. B., F. Takei, and C. M. Doerschuk. 1994. Quanlitation of ICAM-1 expression in mouse lung during pneumonia. J. Immunol. 153:3189.
32. Kang, B.-H., J. D. Crapo, C. D. Wegner, L. G. Letts, and L.-Y. Chang. 1993. Intercellular adhesion molecule-1 expression on the alveolar epithelium and its modification by hypoxia. Am. J. Respir. Cell Mol. Biol. 9:350.
33. Bullard, D. C., E. T. Sandberg, K. Scharfletter-Kochaner, and A. L. Beaudet. 1996. Gene targeting for inflammatory cell adhesion molecules. Inflamm. Res. In press.
34. Ward, P. A. 1995. Adhesion molecule knockouts: one step forward and one step backward. J. Clin. Invest. 95:1425.
35. Kumasaka, T., W. M. Quinlan, N. A. Doyle, T. P. Condon, J. Sligh, F. Takei, A. L. Beuadet, C. F. Bennett, and C. M. Doerschuk. 1996. The role of ICAM-1 in endotoxin-induced pneumonia evaluated using ICAM-1 antisense, anti-ICAM-1 antibodies, and ICAM-1 mutant mice. J. Clin. Invest. 97:2362.
36. Winn, R. K., and J. M. Harlan. 1993. CD18-independent neutrophil and mononuclear leukocyte emigration into the peritoneum of rabbits. J. Clin. Invest. 92: 1168.
37. Wegner, C. D., R. H. Gundel, P. Reilly, N. Haynes, L. G. Letts, and R. Rothlein. 1990. Intercellular adhesion molecules-1 (ICAM-1) in the pathogenesis of asthma. Science 247:456.