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Volumn 2, Issue 2, 2002, Pages 120-128

Interleukin-2-mediated survival and proliferative signals are uncoupled in T lymphocytes that fail to divide after activation

Author keywords

Apoptosis; Cellular proliferation; Cytokines; T lymphocytes

Indexed keywords

GROWTH FACTOR; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B;

EID: 0036487917     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-6143.2002.020202.x     Document Type: Article
Times cited : (6)

References (35)
  • 1
    • 0034283927 scopus 로고    scopus 로고
    • T cell effector function and anergy avoidance are quantitatively linked to cell division
    • Wells AD, Walsh MC, Sankaran D, Turka LA. T cell effector function and anergy avoidance are quantitatively linked to cell division. J Immunol 2000; 165: 2432-2443.
    • (2000) J Immunol , vol.165 , pp. 2432-2443
    • Wells, A.D.1    Walsh, M.C.2    Sankaran, D.3    Turka, L.A.4
  • 2
    • 0031437624 scopus 로고    scopus 로고
    • Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response
    • Wells AD, Gudmundsdottir H, Turka LA. Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response. J Clin Invest 1997; 100: 3173-3183.
    • (1997) J Clin Invest , vol.100 , pp. 3173-3183
    • Wells, A.D.1    Gudmundsdottir, H.2    Turka, L.A.3
  • 3
    • 0033136945 scopus 로고    scopus 로고
    • Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: Effector function is linked to proliferative capacity
    • Gudmundsdottir H, Wells AD, Turka LA. Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: effector function is linked to proliferative capacity. J Immunol 1999; 162: 5212-5223.
    • (1999) J Immunol , vol.162 , pp. 5212-5223
    • Gudmundsdottir, H.1    Wells, A.D.2    Turka, L.A.3
  • 4
    • 0034163579 scopus 로고    scopus 로고
    • The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5
    • Lord JD, McIntosh BC, Greenberg PD, Nelson BH. The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5. J Immunol 2000; 164: 2533-2541.
    • (2000) J Immunol , vol.164 , pp. 2533-2541
    • Lord, J.D.1    McIntosh, B.C.2    Greenberg, P.D.3    Nelson, B.H.4
  • 5
    • 0033199317 scopus 로고    scopus 로고
    • Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death
    • Van Parijs L, Refaeli Y, Lord JD, Nelson BH, Abbas AK, Baltimore D. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity 1999; 11: 281-288.
    • (1999) Immunity , vol.11 , pp. 281-288
    • Van Parijs, L.1    Refaeli, Y.2    Lord, J.D.3    Nelson, B.H.4    Abbas, A.K.5    Baltimore, D.6
  • 6
    • 0027429761 scopus 로고
    • Ligation of CD28 receptor by B7 induces formation of D-3 phosphoinositides in T lymphocytes independently of T cell receptor/CD3 activation
    • Ward SG, Westwick J, Hall ND, Sansom DM. Ligation of CD28 receptor by B7 induces formation of D-3 phosphoinositides in T lymphocytes independently of T cell receptor/CD3 activation. Eur J Immunol 1993; 23: 2572-2577.
    • (1993) Eur J Immunol , vol.23 , pp. 2572-2577
    • Ward, S.G.1    Westwick, J.2    Hall, N.D.3    Sansom, D.M.4
  • 7
    • 0030890933 scopus 로고    scopus 로고
    • Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
    • Ahmed NN, Grimes HL, Bellacosa A, Chan TO, Tsichlis PN. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc Natl Acad Sci USA 1997; 94: 3627-3632.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3627-3632
    • Ahmed, N.N.1    Grimes, H.L.2    Bellacosa, A.3    Chan, T.O.4    Tsichlis, P.N.5
  • 8
    • 0031433335 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F
    • Brennan P, Babbage JW, Burgering BM, Groner B, Reif K, Cantrell DA. Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F. Immunity 1997; 7: 679-689.
    • (1997) Immunity , vol.7 , pp. 679-689
    • Brennan, P.1    Babbage, J.W.2    Burgering, B.M.3    Groner, B.4    Reif, K.5    Cantrell, D.A.6
  • 9
    • 0033537849 scopus 로고    scopus 로고
    • Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling
    • Craddock BL, Orchiston EA, Hinton HJ, Welham MJ. Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling. J Biol Chem 1999; 274: 10633-10640.
    • (1999) J Biol Chem , vol.274 , pp. 10633-10640
    • Craddock, B.L.1    Orchiston, E.A.2    Hinton, H.J.3    Welham, M.J.4
  • 10
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta SR, Dudek H, Tao X et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997; 91: 321-241
    • (1997) Cell , vol.91 , pp. 321-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3
  • 12
    • 0034646644 scopus 로고    scopus 로고
    • Akt/protein kinase B upregulates Bcl-2 expression through cAMP-response element-binding protein
    • Pugazhenthi S, Nesterova A, Sable C et al. Akt/protein kinase B upregulates Bcl-2 expression through cAMP-response element-binding protein. J Biol Chem 2000; 275: 10 761-10 766.
    • (2000) J Biol Chem , vol.275 , pp. 10761-10766
    • Pugazhenthi, S.1    Nesterova, A.2    Sable, C.3
  • 13
    • 0345476290 scopus 로고    scopus 로고
    • Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance
    • Wells AD, Li XC, Liy Y et al. Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. Nat Med 1999; 5: 1303-1307.
    • (1999) Nat Med , vol.5 , pp. 1303-1307
    • Wells, A.D.1    Li, X.C.2    Liy, Y.3
  • 14
    • 0028970662 scopus 로고
    • L displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice
    • L displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice. J Exp Med 1995; 182: 1973-1983.
    • (1995) J Exp Med , vol.182 , pp. 1973-1983
    • Grillot, D.A.1    Merino, R.2    Nunez, G.3
  • 15
    • 0028297141 scopus 로고
    • Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
    • Strasser A, Harris AW, Corcoran LM, Cory S. Bcl-2 expression promotes B- but not T-lymphoid development in scid mice. Nature 1994; 368: 457-460.
    • (1994) Nature , vol.368 , pp. 457-460
    • Strasser, A.1    Harris, A.W.2    Corcoran, L.M.3    Cory, S.4
  • 16
    • 0032475861 scopus 로고    scopus 로고
    • Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
    • Stambolic V, Suzuki A, de la Pompa JL et al. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 1998; 95: 29-39.
    • (1998) Cell , vol.95 , pp. 29-39
    • Stambolic, V.1    Suzuki, A.2    De la Pompa, J.L.3
  • 20
    • 0029938724 scopus 로고    scopus 로고
    • Regulation of cell division cycle progression by bcl-2 expression: A potential mechanism for inhibition of programmed cell death
    • Mazel S, Burtrum D, Petrie HT. Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death. J Exp Med 1996; 183: 2219-2226.
    • (1996) J Exp Med , vol.183 , pp. 2219-2226
    • Mazel, S.1    Burtrum, D.2    Petrie, H.T.3
  • 21
    • 0029843941 scopus 로고    scopus 로고
    • Cross talk between cell death and cell cycle progression: Bcl-2 regulates NFAT-mediated activation
    • Linette GP, Li Y, Roth K, Korsmeyer SJ. Cross talk between cell death and cell cycle progression: Bcl-2 regulates NFAT-mediated activation. Proc Natl Acad Sci USA 1996; 93: 9545-9552.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9545-9552
    • Linette, G.P.1    Li, Y.2    Roth, K.3    Korsmeyer, S.J.4
  • 22
    • 0030794452 scopus 로고    scopus 로고
    • The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry
    • Huang DC, O'Reilly LA, Strasser A, Cory S. The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry. EMBO J 1997; 16: 4628-4638.
    • (1997) EMBO J , vol.16 , pp. 4628-4638
    • Huang, D.C.1    O'Reilly, L.A.2    Strasser, A.3    Cory, S.4
  • 23
    • 0032502801 scopus 로고    scopus 로고
    • Homeostasis and self-tolerance in the immune system: Turning lymphocytes off
    • Van Parijs L, Abbas AK. Homeostasis and self-tolerance in the immune system: turning lymphocytes off. Science 1998; 280: 243-248.
    • (1998) Science , vol.280 , pp. 243-248
    • Van Parijs, L.1    Abbas, A.K.2
  • 24
    • 0032031457 scopus 로고    scopus 로고
    • Functional roles of Fas and Bcl2-regulated apoptosis of T lymphocytes
    • Van Parijs L, Biuckians A, Abbas AK. Functional roles of Fas and Bcl2-regulated apoptosis of T lymphocytes. J Immunol 1998; 160: 2065-2071.
    • (1998) J Immunol , vol.160 , pp. 2065-2071
    • Van Parijs, L.1    Biuckians, A.2    Abbas, A.K.3
  • 25
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance
    • Van Parijs L, Ibraghimov A, Abbas AK. The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity 1996; 4: 321-328.
    • (1996) Immunity , vol.4 , pp. 321-328
    • Van Parijs, L.1    Ibraghimov, A.2    Abbas, A.K.3
  • 26
    • 0032005484 scopus 로고    scopus 로고
    • The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens
    • Van Parijs L, Peterson DA, Abbas AK. The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity 1998; 8: 265-274.
    • (1998) Immunity , vol.8 , pp. 265-274
    • Van Parijs, L.1    Peterson, D.A.2    Abbas, A.K.3
  • 27
    • 0031007962 scopus 로고    scopus 로고
    • Elevated expression of Bcl-2 and Bcl-x by intestinal intraepithelial lymphocytes: Resistance to apoptosis by glucocorticoids and irradiation
    • et al. Hallam TA, Chilton DG, Gourley WK et al. Elevated expression of Bcl-2 and Bcl-x by intestinal intraepithelial lymphocytes: resistance to apoptosis by glucocorticoids and irradiation. Int Immunol 1997; 9: 945-953.
    • (1997) Int Immunol , vol.9 , pp. 945-953
    • Hallam, T.A.1    Chilton, D.G.2    Gourley, W.K.3
  • 29
    • 1442342360 scopus 로고    scopus 로고
    • Following the development of a CD4 T cell response in vivo: From activation to memory formation
    • Garcia S, DiSanto J, Stockinger B. Following the development of a CD4 T cell response in vivo: from activation to memory formation. Immunity 1999; 11: 163-171.
    • (1999) Immunity , vol.11 , pp. 163-171
    • Garcia, S.1    DiSanto, J.2    Stockinger, B.3
  • 30
    • 0028172867 scopus 로고
    • Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin
    • Nourse J, Firpo E, Flanagan WM et al. Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin. Nature 1994; 372: 570-573.
    • (1994) Nature , vol.372 , pp. 570-573
    • Nourse, J.1    Firpo, E.2    Flanagan, W.M.3
  • 31
    • 0033136697 scopus 로고    scopus 로고
    • Anchorage dependence of mitogen-induced G1 to S transition in primary T lymphocytes
    • Geginat J, Bossi G, Bender JR, Pardi R. Anchorage dependence of mitogen-induced G1 to S transition in primary T lymphocytes. J Immunol 1999; 162: 5085-5093.
    • (1999) J Immunol , vol.162 , pp. 5085-5093
    • Geginat, J.1    Bossi, G.2    Bender, J.R.3    Pardi, R.4
  • 32
    • 0032515027 scopus 로고    scopus 로고
    • Regulation of cell death protease caspase-9 by phosphorylation
    • Cardone MH, Roy N, Stennicke HR et al. Regulation of cell death protease caspase-9 by phosphorylation. Science 1998; 282: 1318-1321.
    • (1998) Science , vol.282 , pp. 1318-1321
    • Cardone, M.H.1    Roy, N.2    Stennicke, H.R.3
  • 34
    • 0033517189 scopus 로고    scopus 로고
    • NFkappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
    • Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. NFkappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 1999; 401: 82-85.
    • (1999) Nature , vol.401 , pp. 82-85
    • Ozes, O.N.1    Mayo, L.D.2    Gustin, J.A.3    Pfeffer, S.R.4    Pfeffer, L.M.5    Donner, D.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.