Restricted ability of human mast cell tryptase to activate proteinase-activated receptor-2 in rat aorta

Canadian Journal of Physiology and Pharmacology

Volumn 80, Issue 10, 2002, Pages 987-992

  Compton, Steven J ^a,b   McGuire, John J ^a   Saifeddine, Mahmoud ^a   Hollenberg, Morley D ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b CASTLE HILL HOSPITAL   (United Kingdom)

Author keywords

Cardiovascular system; PAR2; Protease; Tryptase

Indexed keywords

ACETYLCHOLINE; HEPARIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PEPTIDE; PHENYLEPHRINE; PROTEINASE ACTIVATED RECEPTOR 2; SERYLLEUCYLISOLEUCYLGLYCYLARGINYLLEUCINAMIDE; SIALIC ACID; SIALIDASE; TRYPSIN; TRYPTASE; UNCLASSIFIED DRUG; MCPT6 PROTEIN, RAT; OLIGOPEPTIDE; SERINE PROTEINASE; SERYL LEUCYL ISOLEUCYL GLYCYL ARGINYL LEUCINAMIDE; SERYL-LEUCYL-ISOLEUCYL-GLYCYL--ARGINYL-LEUCINAMIDE; THROMBIN RECEPTOR; TPSB1 PROTEIN, RAT; VASODILATOR AGENT;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY DILATATION; ARTICLE; BIOASSAY; CELL SURFACE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; MAST CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; RECEPTOR UPREGULATION; THORACIC AORTA; VASCULAR ENDOTHELIUM; VASCULAR RING; ANIMAL; DRUG POTENTIATION; ENZYMOLOGY; HUMAN; IN VITRO STUDY; MALE; METABOLISM; MUSCLE CONTRACTION; MUSCLE RELAXATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ANIMALS; AORTA, THORACIC; HUMANS; MALE; MAST CELLS; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; NEURAMINIDASE; OLIGOPEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, PAR-2; RECEPTORS, THROMBIN; SERINE ENDOPEPTIDASES; TRYPSIN; TRYPTASES; VASODILATION; VASODILATOR AGENTS;

EID: 0036444721     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y02-125     Document Type: Article

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