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Volumn 13, Issue 1, 2002, Pages 19-27

The angiopoietins and Tie2/Tek: Adding to the complexity of cardiovascular development

Author keywords

Angiogenesis; Angiopoietin; Development; Endothelial cell; Tie2

Indexed keywords

ANGIOPOIETIN; ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; INTERCELLULAR ADHESION MOLECULE 1; RECEPTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN;

EID: 0036444180     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1006/scdb.2001.0288     Document Type: Article
Times cited : (131)

References (58)
  • 1
    • 0033117167 scopus 로고    scopus 로고
    • Extracellular matrix-driven matrix metalloproteinase production in endothelial cells: Implications for angiogenesis
    • Haas TL, Madri JA (1999) Extracellular matrix-driven matrix metalloproteinase production in endothelial cells: Implications for angiogenesis. Trends Cardiovasc Med 9:70-77
    • (1999) Trends Cardiovasc Med , vol.9 , pp. 70-77
    • Haas, T.L.1    Madri, J.A.2
  • 2
    • 0035120643 scopus 로고    scopus 로고
    • Cellular interactions in vascular growth and differentiation
    • Nguyen LL, D'Amore PA (2001) Cellular interactions in vascular growth and differentiation. Int Rev Cytol 204:1-48
    • (2001) Int Rev Cytol , vol.204 , pp. 1-48
    • Nguyen, L.L.1    D'Amore, P.A.2
  • 3
    • 0034468383 scopus 로고    scopus 로고
    • Eph receptors and ephrin ligands, essential mediators of vascular development
    • Adam RH, Klein R (2001) Eph receptors and ephrin ligands, essential mediators of vascular development. Trends Cardiovasc Med 10:183-188
    • (2001) Trends Cardiovasc Med , vol.10 , pp. 183-188
    • Adam, R.H.1    Klein, R.2
  • 4
    • 0035318510 scopus 로고    scopus 로고
    • Tie receptors: New modulators of angiogenic and lymphangiogenic and angiogenic responses
    • Jones N, Iljin K, Dumont DJ, Alitalo K (2001) Tie receptors: New modulators of angiogenic and lymphangiogenic and angiogenic responses. Nat Rev Mol Cell Biol 2:257-267
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 257-267
    • Jones, N.1    Iljin, K.2    Dumont, D.J.3    Alitalo, K.4
  • 5
    • 0033047875 scopus 로고    scopus 로고
    • VEGFs, receptors and angiogenesis
    • Veikkola T, Alitalo K (1999) VEGFs, receptors and angiogenesis. Semin Cancer Biol 9:211-220
    • (1999) Semin Cancer Biol , vol.9 , pp. 211-220
    • Veikkola, T.1    Alitalo, K.2
  • 6
    • 0343920277 scopus 로고    scopus 로고
    • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    • Carmeliet P et al. (1996) Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380:435-439
    • (1996) Nature , vol.380 , pp. 435-439
    • Carmeliet, P.1
  • 7
    • 0034985151 scopus 로고    scopus 로고
    • A novel role for VEGF in endocardial cushion formation and its potential contribution to congenital heart defects
    • Dor Y, Camenisch TD, Itin A, Fishman GI, McDonald JA, Carmeliet P, Keshet E (2001) A novel role for VEGF in endocardial cushion formation and its potential contribution to congenital heart defects. Development 128:1531-1538
    • (2001) Development , vol.128 , pp. 1531-1538
    • Dor, Y.1    Camenisch, T.D.2    Itin, A.3    Fishman, G.I.4    McDonald, J.A.5    Carmeliet, P.6    Keshet, E.7
  • 9
    • 0030460424 scopus 로고    scopus 로고
    • Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
    • Davis S et al. (1996) Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 87:1161-1169
    • (1996) Cell , vol.87 , pp. 1161-1169
    • Davis, S.1
  • 10
    • 15144358851 scopus 로고    scopus 로고
    • Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
    • Maisonpierre PC et al. (1997) Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277:55-60
    • (1997) Science , vol.277 , pp. 55-60
    • Maisonpierre, P.C.1
  • 11
    • 13044292625 scopus 로고    scopus 로고
    • Angiopoietins 3 and 4: Diverging gene counterparts in mice and humans
    • Valenzuela DM et al. (1999) Angiopoietins 3 and 4: Diverging gene counterparts in mice and humans. Proc Natl Acad Sci USA 96:1904-1909
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1904-1909
    • Valenzuela, D.M.1
  • 12
    • 0026695259 scopus 로고
    • Tek, a novel tyrosin kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors
    • Dumont DJ, Yamaguchi TP, Conlon RA, Rossant J, Breitman ML (1992) Tek, a novel tyrosin kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors. Oncogene 7:1471-1480
    • (1992) Oncogene , vol.7 , pp. 1471-1480
    • Dumont, D.J.1    Yamaguchi, T.P.2    Conlon, R.A.3    Rossant, J.4    Breitman, M.L.5
  • 13
    • 0033570185 scopus 로고    scopus 로고
    • Angiopoietin-1 and -2 coiled coil domains mediate distinct homooligomerization patterns, but fibrinogen like domains mediate ligand activity
    • Procopio WN, Pelavin PI, Lee WM, Yeilding NM (1999) Angiopoietin-1 and -2 coiled coil domains mediate distinct homooligomerization patterns, but fibrinogen like domains mediate ligand activity. J Biol Chem 274:30196-30201
    • (1999) J Biol Chem , vol.274 , pp. 30196-30201
    • Procopio, W.N.1    Pelavin, P.I.2    Lee, W.M.3    Yeilding, N.M.4
  • 14
    • 0035860806 scopus 로고    scopus 로고
    • Angiopoietin-1, unlike angiopoietin-2, is incorporated into the extracellular matrix via its linker peptide region
    • Xu Y, Yu Q (2001) Angiopoietin-1, unlike angiopoietin-2, is incorporated into the extracellular matrix via its linker peptide region. J Biol Chem 276:34990-34998
    • (2001) J Biol Chem , vol.276 , pp. 34990-34998
    • Xu, Y.1    Yu, Q.2
  • 15
    • 0032541165 scopus 로고    scopus 로고
    • Chemotactic properties of angiopoietin-1, and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie2
    • Witzenbichler B, Maisonpierre PC, Jones P, Yancopoulos GD, Isner JM (1998) Chemotactic properties of angiopoietin-1, and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie2. J Biol Chem 273:18514-18521
    • (1998) J Biol Chem , vol.273 , pp. 18514-18521
    • Witzenbichler, B.1    Maisonpierre, P.C.2    Jones, P.3    Yancopoulos, G.D.4    Isner, J.M.5
  • 16
    • 0032714316 scopus 로고    scopus 로고
    • Angiopoietin-1 and its receptor tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells
    • Hayes AJ, Huang WQ, Mallah J, Yang D, Lippman ME, Li LY (1999) Angiopoietin-1 and its receptor tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells. Microvasc Res 58:224-237
    • (1999) Microvasc Res , vol.58 , pp. 224-237
    • Hayes, A.J.1    Huang, W.Q.2    Mallah, J.3    Yang, D.4    Lippman, M.E.5    Li, L.Y.6
  • 17
    • 0006677050 scopus 로고    scopus 로고
    • Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway
    • Kim I, Kim HG, So J-N, Kim JH, Kwak HJ, Koh GY (2000) Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Circ Res 86:24-29
    • (2000) Circ Res , vol.86 , pp. 24-29
    • Kim, I.1    Kim, H.G.2    So, J.-N.3    Kim, J.H.4    Kwak, H.J.5    Koh, G.Y.6
  • 18
    • 0031834338 scopus 로고    scopus 로고
    • Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt
    • Kontos CD, Stauffer TP, Yang WP, York JD, Huang L, Blanar MA, Meyer T, Peters KG (1998) Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt. Mol Cell Biol 18:4131-4140
    • (1998) Mol Cell Biol , vol.18 , pp. 4131-4140
    • Kontos, C.D.1    Stauffer, T.P.2    Yang, W.P.3    York, J.D.4    Huang, L.5    Blanar, M.A.6    Meyer, T.7    Peters, K.G.8
  • 20
    • 0342657703 scopus 로고    scopus 로고
    • Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion
    • Kim I, Kim HG, Moon SO, Chae SW, So JN, Koh KN, Ahn BC, Koh GY (2000) Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion. Circ Res 86:952-959
    • (2000) Circ Res , vol.86 , pp. 952-959
    • Kim, I.1    Kim, H.G.2    Moon, S.O.3    Chae, S.W.4    So, J.N.5    Koh, K.N.6    Ahn, B.C.7    Koh, G.Y.8
  • 21
    • 0033134622 scopus 로고    scopus 로고
    • Matrix metalloproteinases in angiogenesis: A moving target for therapeutic intervention
    • Stetler-Stevenson WG (1999) Matrix metalloproteinases in angiogenesis: A moving target for therapeutic intervention. J Clin Invest 103:1237-1241
    • (1999) J Clin Invest , vol.103 , pp. 1237-1241
    • Stetler-Stevenson, W.G.1
  • 22
    • 0032695794 scopus 로고    scopus 로고
    • Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration
    • Jones N, Master Z, Jones J, Bouchard D, Gunji Y, Sasaki H, Daly R, Alitalo K, Dumont DJ (1999) Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration. J Biol Chem 274:30896-30905
    • (1999) J Biol Chem , vol.274 , pp. 30896-30905
    • Jones, N.1    Master, Z.2    Jones, J.3    Bouchard, D.4    Gunji, Y.5    Sasaki, H.6    Daly, R.7    Alitalo, K.8    Dumont, D.J.9
  • 24
    • 0035503218 scopus 로고    scopus 로고
    • Dok-R plays a pivotal role in angiopoietin-1 mediated cell migration through activation of Pak
    • Master Z, Jones N, Tran J, Kerbel S, Dumont DJ (2001) Dok-R plays a pivotal role in angiopoietin-1 mediated cell migration through activation of Pak. EMBO J 20:5919-5928
    • (2001) EMBO J , vol.20 , pp. 5919-5928
    • Master, Z.1    Jones, N.2    Tran, J.3    Kerbel, S.4    Dumont, D.J.5
  • 26
    • 0033598172 scopus 로고    scopus 로고
    • Recruitment of dok-R to the EGF receptor through its PTB domain is required for attenuation of erk MAP kinase activation
    • Jones N, Dumont DJ (1999) Recruitment of dok-R to the EGF receptor through its PTB domain is required for attenuation of erk MAP kinase activation. Curr Biol 9:1057-1060
    • (1999) Curr Biol , vol.9 , pp. 1057-1060
    • Jones, N.1    Dumont, D.J.2
  • 27
    • 0028973594 scopus 로고
    • GRB2 and SH-PTP2; potentially important endothelial signaling molecules downstream of the TEK/TIE2 receptor tyrosine kinase
    • Huang L, Turck CW, Rao P, Peters KG (1995) GRB2 and SH-PTP2; potentially important endothelial signaling molecules downstream of the TEK/TIE2 receptor tyrosine kinase. Oncogene 11:2097-2103
    • (1995) Oncogene , vol.11 , pp. 2097-2103
    • Huang, L.1    Turck, C.W.2    Rao, P.3    Peters, K.G.4
  • 28
    • 0034648666 scopus 로고    scopus 로고
    • Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway
    • Kim I, Kim JH, Moon SO, Kwak HJ, Kim NG, Koh GY (2000) Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Oncogene 19:4549-4552
    • (2000) Oncogene , vol.19 , pp. 4549-4552
    • Kim, I.1    Kim, J.H.2    Moon, S.O.3    Kwak, H.J.4    Kim, N.G.5    Koh, G.Y.6
  • 29
    • 0028122465 scopus 로고
    • Dominant-negative and targeted null mutations in the endothelial receptor tyrosin kinase, tek, reveal a critical role in vasculogenesis of the embryo
    • Dumont DJ, Gradwohl G, Fong GH, Puri MC, Gertsenstein M, Auerbach A, Breitman ML (1994) Dominant-negative and targeted null mutations in the endothelial receptor tyrosin kinase, tek, reveal a critical role in vasculogenesis of the embryo. Genes Dev 8:1897-1909
    • (1994) Genes Dev , vol.8 , pp. 1897-1909
    • Dumont, D.J.1    Gradwohl, G.2    Fong, G.H.3    Puri, M.C.4    Gertsenstein, M.5    Auerbach, A.6    Breitman, M.L.7
  • 30
    • 0031845695 scopus 로고    scopus 로고
    • TIE1 and TIE2 receptor tyrosine kinases inversely regulate embryonic angiogenesis by the mechanism of intussusceptive microvascular growth
    • Patan S (1998) TIE1 and TIE2 receptor tyrosine kinases inversely regulate embryonic angiogenesis by the mechanism of intussusceptive microvascular growth. Microvasc Res 56:1-21
    • (1998) Microvasc Res , vol.56 , pp. 1-21
    • Patan, S.1
  • 32
    • 0032693760 scopus 로고    scopus 로고
    • Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development
    • Puri MC, Partanen J, Rossant J, Bernstein A (1999) Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development. Development 126:4569-4580
    • (1999) Development , vol.126 , pp. 4569-4580
    • Puri, M.C.1    Partanen, J.2    Rossant, J.3    Bernstein, A.4
  • 33
    • 0034984712 scopus 로고    scopus 로고
    • Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function
    • Jones N, Voskas D, Master Z, Sarao R, Jones J, Dumont DJ (2001) Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function. EMBO Rep 2:438-445
    • (2001) EMBO Rep , vol.2 , pp. 438-445
    • Jones, N.1    Voskas, D.2    Master, Z.3    Sarao, R.4    Jones, J.5    Dumont, D.J.6
  • 35
    • 0035101667 scopus 로고    scopus 로고
    • A combinatorial role of angiopoietin-1 and orphan receptor TIE1
    • Loughna S, Sato TN (2001) A combinatorial role of angiopoietin-1 and orphan receptor TIE1. Mol Cell 7:233-239
    • (2001) Mol Cell , vol.7 , pp. 233-239
    • Loughna, S.1    Sato, T.N.2
  • 39
    • 0032770343 scopus 로고    scopus 로고
    • Allelic and locus heterogeneity in inherited venous malformations
    • Calvert JT et al. (1999) Allelic and locus heterogeneity in inherited venous malformations. Hum Mol Genet 8:1279-1289
    • (1999) Hum Mol Genet , vol.8 , pp. 1279-1289
    • Calvert, J.T.1
  • 40
    • 0030460775 scopus 로고    scopus 로고
    • Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2
    • Vikkula M et al. (1996) Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2. Cell 87:1181-1190
    • (1996) Cell , vol.87 , pp. 1181-1190
    • Vikkula, M.1
  • 42
    • 0035134082 scopus 로고    scopus 로고
    • Angiopoietin-2 is implicated in the regulation of tumor angiogenesis
    • Yu Q, Stamenkovic I (2001) Angiopoietin-2 is implicated in the regulation of tumor angiogenesis. Am J Pathol 158:563-570
    • (2001) Am J Pathol , vol.158 , pp. 563-570
    • Yu, Q.1    Stamenkovic, I.2
  • 44
    • 0033902655 scopus 로고    scopus 로고
    • Expression of Tie1, Tie2, and angiopoietins 1, 2, and 4 in Kaposi's sarcoma and cutaneous angiosarcoma
    • Brown LF, Dezube BJ, Tognazzi K, Dvorak HF, Yancopoulos GD (2000) Expression of Tie1, Tie2, and angiopoietins 1, 2, and 4 in Kaposi's sarcoma and cutaneous angiosarcoma. Am J Pathol 156:2179-2183
    • (2000) Am J Pathol , vol.156 , pp. 2179-2183
    • Brown, L.F.1    Dezube, B.J.2    Tognazzi, K.3    Dvorak, H.F.4    Yancopoulos, G.D.5
  • 45
    • 0028670845 scopus 로고
    • Enhanced expression of the tie receptor tyrosin kinase messenger RNA in the vascular endothelium of metastatic melanomas
    • Kaipainen A, Vlaykova T, Hatva E, Bohling T, Jekunen A, Pyrhonen S, Alitalo K (1994) Enhanced expression of the tie receptor tyrosin kinase messenger RNA in the vascular endothelium of metastatic melanomas. Cancer Res 54:6571-6577
    • (1994) Cancer Res , vol.54 , pp. 6571-6577
    • Kaipainen, A.1    Vlaykova, T.2    Hatva, E.3    Bohling, T.4    Jekunen, A.5    Pyrhonen, S.6    Alitalo, K.7
  • 47
    • 0031737425 scopus 로고    scopus 로고
    • Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis
    • Stratmann A, Risau W, Plate KH (1998) Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis. Am J Pathol 153:1459-1466
    • (1998) Am J Pathol , vol.153 , pp. 1459-1466
    • Stratmann, A.1    Risau, W.2    Plate, K.H.3
  • 48
    • 13144254247 scopus 로고    scopus 로고
    • Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosin kinase Tie2
    • Lin P et al. (1998) Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosin kinase Tie2. Proc Natl Acad Sci USA 95:8829-8834
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8829-8834
    • Lin, P.1
  • 49
    • 0030726988 scopus 로고    scopus 로고
    • Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth
    • Lin P, Polverini P, Dewhirst M, Shan S, Rao PS, Peters K (1997) Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth. J Clin Invest 100:2072-2078
    • (1997) J Clin Invest , vol.100 , pp. 2072-2078
    • Lin, P.1    Polverini, P.2    Dewhirst, M.3    Shan, S.4    Rao, P.S.5    Peters, K.6
  • 50
    • 0033168916 scopus 로고    scopus 로고
    • Two independent mechanisms essential for tumor angiogenesis: Inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway
    • Siemeister G, Schirner M, Weindel K, Reusch P, Menrad A, Marme D, Martiny-Baron G (1999) Two independent mechanisms essential for tumor angiogenesis: Inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway. Cancer Res 59:3185-3191
    • (1999) Cancer Res , vol.59 , pp. 3185-3191
    • Siemeister, G.1    Schirner, M.2    Weindel, K.3    Reusch, P.4    Menrad, A.5    Marme, D.6    Martiny-Baron, G.7
  • 51
    • 8544253996 scopus 로고    scopus 로고
    • Analysis of Tie receptor tyrosin kinase in haemopoietic progenitor and leukaemia cells
    • Kukk E et al. (1997) Analysis of Tie receptor tyrosin kinase in haemopoietic progenitor and leukaemia cells. Br J Haematol 98:195-203
    • (1997) Br J Haematol , vol.98 , pp. 195-203
    • Kukk, E.1
  • 52
    • 0028867704 scopus 로고
    • The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells
    • Puri MC, Rossant J, Alitalo K, Bernstein A, Partanen J (1995) The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells. EMBO J 14:5884-5891
    • (1995) EMBO J , vol.14 , pp. 5884-5891
    • Puri, M.C.1    Rossant, J.2    Alitalo, K.3    Bernstein, A.4    Partanen, J.5
  • 55
    • 0035821293 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells
    • Hattori K et al. (2001) Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells. J Exp Med 193:1005-1014
    • (2001) J Exp Med , vol.193 , pp. 1005-1014
    • Hattori, K.1
  • 57
    • 0035860845 scopus 로고    scopus 로고
    • Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression
    • Kim I, Moon SO, Park SK, Chae SW, Koh GY (2001) Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression. Circ Res 89:477-479
    • (2001) Circ Res , vol.89 , pp. 477-479
    • Kim, I.1    Moon, S.O.2    Park, S.K.3    Chae, S.W.4    Koh, G.Y.5
  • 58
    • 0344418721 scopus 로고    scopus 로고
    • Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation
    • Yuan HT, Suri C, Yancopoulos GD, Woolf AS (1999) Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation. J Am Soc Nephrol 10:1722-1736
    • (1999) J Am Soc Nephrol , vol.10 , pp. 1722-1736
    • Yuan, H.T.1    Suri, C.2    Yancopoulos, G.D.3    Woolf, A.S.4


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