Selective modification at the N-terminal region of human growth hormone that shows antagonistic activity

Molecular and Cellular Endocrinology

Volumn 130, Issue 1-2, 1997, Pages 141-152

  Tchelet, A ^b   Vogel, T ^d   Helman, D ^a   Guy, R ^d   Neospouolus, C ^c   Goffin, V ^b   Djiane, J ^c   Gertler, A ^a,c  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b INSERM   (France)

^c CEMAGREF   (France)

^d Biotechnology General   (Israel)

Author keywords

Antagonist; Human growth hormone; In vitro biological activity; Lactogen; Receptors; Site directed mutagenesis; Somatogen

Indexed keywords

GROWTH HORMONE RECEPTOR; HORMONE RECEPTOR BLOCKING AGENT; HORMONE RECEPTOR STIMULATING AGENT; HUMAN GROWTH HORMONE; MUTANT PROTEIN; PROLACTIN RECEPTOR; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CIRCULAR DICHROISM; CONTROLLED STUDY; ESCHERICHIA COLI; GEL FILTRATION; HORMONE ACTION; HORMONE RECEPTOR INTERACTION; HORMONE STRUCTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING, COMPETITIVE; CATTLE; CELL DIVISION; CELL LINE; CLONING, MOLECULAR; ESCHERICHIA COLI; FEMALE; GROWTH HORMONE; HUMAN GROWTH HORMONE; HUMANS; MICE; PEPTIDE FRAGMENTS; PROTEIN FOLDING; RABBITS; RECEPTORS, PROLACTIN; RECEPTORS, SOMATOTROPIN; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 0030872848     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(97)00084-1     Document Type: Article

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