17 Prions of yeast as epigenetic phenomena: High protein "copy number" inducing protein "silencing"

Advances in Genetics

Volumn 46, Issue , 2002, Pages 485-525

  Wickner, Reed B ^a,b,c   Edskes, Herman K ^a,b,c   Roberts, B Tibor ^a,b,c   Pierc, Michael ^a,b,c   Baxa, Ulrich ^a,b,c  

^a Department of Dermatopathology   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; CHAPERONE; CYCLIC AMP; NITROGEN; RAS PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; URE2 PROTEIN, S CEREVISIAE;

AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; FUNGAL GENE; GENE SILENCING; GENETICS; METABOLISM; MOLECULAR GENETICS; PRION; PRION DISEASE; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; REVIEW; YEAST;

AMINO ACID SEQUENCE; AMYLOID; ANIMALS; CYCLIC AMP; GENE SILENCING; GENES, FUNGAL; MODELS, GENETIC; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; NITROGEN; PRION DISEASES; PRIONS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RAS PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; YEASTS;

EID: 0036366021     PISSN: 00652660     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0065-2660(02)46018-X     Document Type: Chapter

References (132)

1. Aigle M. Contribution a l'etude de l'heredite non-chromosomique de Saccharomyces cerevisiae facteur [URE3] et plasmides hybrides 1979 L'Universite Louis Pasteur de Strasbourg, Strasbourg France 95
2. Aigle M. Lacroute F. Genetical aspects of [URE3], a non-Mendelian, cytoplasmically inherited mutation in yeast Mol. Gen. Genet. 136 1975 327 335
3. Alper T. Cramp W.A. Haig D.A. Clarke M.C. Does the agent of scrapie replicate without nucleic acid? Nature 214 1967 764 766
4. Alper T. Haig D.A. Clarke M.C. The exceptionally small size of the scrapie agent Biochem. Biophys. Res. Commun. 22 1966 278 284
5. Atencio D. Yaffe M. MAS5 , a yeast homolog of DnaJ involved in mitochondrial import Mol. Cell. Biol. 12 1992 283 291
6. Beck T. Hall M.N. The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors Nature 402 1999 689 692
7. Becker J. Walter W. Yan W. Craig E.A. Functional interaction of cytosolic hsp70 and a DnaJ-related protein, Ydj1p, in protein translocation in vivo Mol. Cell. Biol. 16 1996 4378 4386
8. Begueret J. Turq B. Clave C. Vegetative incompatibility in filamentous fungi: het genes begin to talk Trends Genet. 10 1994 441 446
9. Beisson J. Sonneborn T.M. Cytoplasmic inheritance of the organization of the cell cortex in Paramecium aurelia Proc. Natl. Acad. Sci. USA 53 1965 275 282
10. Beisson-Schecroun J. Incompatibilte cellulaire et interactions nucleo-cytoplasmiques dans les phenomenes de barrage chez Podospora anserina Ann. Genet. 4 1962 3 50
11. Bell L.R. Horabin J.L. Schedl P. Cline T.W. Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila Cell 65 1991 229 239
12. Bessen R.A. Kocisko D.A. Raymond G.J. Nandan S. Landsbury P.T. Caughey B. Non-genetic propagation of strain-specific properties of scrapie prion protein Nature 375 1995 698 700
13. Bolton D.C. McKinley M.P. Prusiner S.B. Identification of a protein that purifies with the scrapie prion Science 218 1982 1309 1311
14. Bousset L. Beirhali H. Janin J. Melki R. Morera S. Structure of the globular region of the prion protein Ure2 from the yeast Saccharomyces cerevisiae Structure 9 2001 39 46
15. Bueler H. Aguzzi A. Sailer A. Greiner R.-A. Autenried P. Aguet M. Weissmann C. Mice devoid of PrP are resistant to Scrapie Cell 73 1993 1339 1347
16. Caplan A. Douglas M.G. Characterization of YDJ1: A yeast homolog of the bacterial dnaJ protein J. Cell Biol. 114 1991 609 621
17. Cardenas M.E. Cutler N.S. Lorenz M.C. Di Como C.J. Heitman J. The TOR signaling cascade regulates gene expression in response to nutrients Genes Dev. 13 1999 3271 3279
18. Carlson G.A. Kingsbury D.T. Goodman P.A. Coleman S. Marshall S.T. DeArmond S. Westaway D. Prusiner S.B. Linkagae of prion protein and scrapie incubation time genes Cell 46 1986 503 511
19. Chabry J. Caughey B. Chesebro B. Specific inhibition of in vitro formation of protease-resistant prion protein by synthetic peptides J. Biol. Chem. 273 1998 13203 13207
20. Chernoff Y.O. Derkach I.L. Inge-Vechtomov S.G. Multicopy SUP35 gene induces de-novo appearance of psi-like factors in the yeast Saccharomyces cerevisiae Curr. Genet. 24 1993 268 270
21. Chernoff Y.O. Galkin A.P. Lewitin E. Chernova T.A. Newnam G.P. Belenkly S.M. Evolutionary conservation of prion-forming abilities of the yeast Sup35 protein Mol. Microbiol. 35 2000 865 876
22. +] Science 268 1995 880 884
23. Chernoff Y.O. Newnam G.P. Kumar J. Allen K. Zink A.D. Evidence for a protein mutator in yeast: Role of the Hsp70-related chaperone Ssb in formation, stability and toxicity of the [PSI+] prion Mol. Cell. Biol. 19 1999 8103 8112
24. Chernoff Y.O. Ono B.-I. Dosage-dependent modifiers of PSI-dependent omnipotent suppression in yeast Brown A.J.P. Tuite M.F. McCarthy J.E.G. Protein Synthesis and Targeting in Yeast 1992 Springer-Verlag Berlin 101 107
25. Chesebro B. BSE and prions: Uncertainties about the agent Science 279 1998 42 43
26. Chesebro B. Race R. Wehrly K. Nishio J. Bloom M. Lechner D. Bergstrom S. Robbins K. Mayer L. Keith J.M. Garon C. Hasse A. Identification of scrapie prion protein-specific mRNA in scrapie-infected brain Nature 315 1985 331 333
27. Choi J.H. Lou W. Vancura A. A novel membrane-bound glutathione S-transferase functions in the statioinary phase of the yeast Saccharomyces cerevisiae J. Biol. Chem. 273 1998 19922 29915
28. Cooper T.G. Nitrogen metabolism in Saccharomyces cerevisiae Strathern J.N. Jones E.W. Broach J.R. The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression Vol. 2 1982 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY 39 99
29. Coschigano P.W. Magasanik B. The URE2 gene product of Saccharomyces cerevisiae plays an important role in the cellular response to the nitrogen source and has homology to glutathione S-transferases Mol. Cell. Biol. 11 1991 822 832
30. Coustou V. Deleu C. Saupe S. Begueret J. The protein product of the het-s heterokaryon incompatibility gene of the fungus Podospora anserina behaves as a prion analog Proc. Natl. Acad. Sci. USA 94 1997 9773 9778
31. Coustou V. Deleu C. Saupe S.J. Begueret J. Mutational analysis of the [Het-s] prion analog of Podospora anserina : A short N-terminal peptide allows prion propagation Genetics 153 1999 1629 1640
32. Cox B.S. PSI, a cytoplasmic suppressor of super-suppressor in yeast Heredity 20 1965 505 521
33. Cox B.S. A recessive lethal super-suppressor mutation in yeast and other PSI phenomena Heredity 26 1971 211 232
34. Cox B.S. Tuite M.F. McLaughlin C.S. The Psi factor of yeast: A problem in inheritance Yeast 4 1988 159 179
35. Craig E.A. The heat-shock response of Saccharomyces cerevisiae Jones E.W. Pringle J.R. Broach J.R. The Molecular and Cellular Biology of the Yeast Saccharomyces vol. 2 1992 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY 501 573
36. Deleu C. Clave C. Begueret J. A single amino acid difference is sufficient to elicit vegetative incompatibility in the fungus Podospora anserina Genetics 135 1993 45 52
37. DePace A.H. Santoso A. Hillner P. Weissman J.S. A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion Cell 93 1998 1241 1252
38. Derkatch I.L. Bradley M.E. Hong J.Y. Liebman S.W. Prions affect the appearance of other prions: the story of [ PIN ] Cell 106 2001 171 182
39. Derkatch I.L. Bradley M.E. Liebman S.W. Overexpression of the SUP45 gene encoding a Sup35p-binding protein inhibits the induction of the de novo appearance of the [ PSI +]prion Proc. Natl. Acad. Sci. USA 95 1998 2400 2405
40. Derkatch I.L. Bradley M.E. Masse S.V. Zadorsky S.P. Polozkov G.V. Inge-Vechtomov S.G. Liebman S.W. Dependence and independence of [PSI(+)] and [PIN(+)]: A two-prion system in yeast? EMBO J. 19 2000 1942 1952
41. Derkatch I.L. Bradley M.E. Zhou P. Chernoff Y.O. Liebman S.W. Genetic and environmental factors affecting the de novo appearance of the [PSI+] prion in Saccharomyces cerevisiae Genetics 147 1997 507 519
42. Derkatch I.L. Chernoff Y.O. Kushnirov V.V. Inge-Vechtomov S.G. Liebman S.W. Genesis and variability of [PSI] prion factors in Saccharomyces cerevisiae Genetics 144 1996 1375 1386
43. Dickinson A.G. Meikle V.M.H. Fraser H. Identification of a gene which controls the incubation period of some strains of scrapie in mice J. Comp. Pathol 78 1968 293 299
44. Doel S.M. McCready S.J. Nierras C.R. Cox B.S. The dominant PNM2- mutation which eliminates the [PSI] factor of Saccharomyces cerevisiae is the result of a missense mutation in the SUP35 gene Genetics 137 1994 659 670
45. Eaglestone S.S. Cox B.S. Tuite M.F. Translation termination efficiency can be regulated in Saccharomyces cerevisiae by environmental stress through a prion-mediated mechanism EMBO J. 18 1999 1974 1981
46. Eaglestone S.S. Ruddock L.W. Cox B.S. Tuite M.F. Guanidine hydrochloride blocks a critical step in the propagation of the prion-like determinant [ PSI +] of Saccharomyces cerevisiae Proc. Natl. Acad. Sci. USA 97 2000 240 244
47. Edskes H.K. Gray V.T. Wickner R.B. The [URE3] prion is an aggregated form of Ure2p that can be cured by overexpression of Ure2p fragments Proc. Natl. Acad. Sci. USA 96 1999 1498 1503
48. Edskes H.K. Hanover J.A. Wickner R.B. Mks1p is a regulator of nitrogen catabolism upstream of Ure2p in Saccharomyces cerevisiae Genetics 153 1999 585 594
49. Edskes H.K. Wickner R.B. A protein required for prion generation: [URE3] induction requires the Ras-regulated Mks1 protein Proc. Natl. Acad. Sci. USA 97 2000 6625 6629
50. Farquhar C.F. Somerville R.A. Bruce M.E. Straining the prion hypothesis Nature 391 1998 345 346
51. Feller A. Ramos F. Peirard A. Dubois E. Lys80p of Saccharomyces cerevisiae , previously proposed as a specific repressor of LYS genes, is a pleiotropic regulatory factor identical to Mks1p Yeast 13 1997 1337 1346
52. Fernandez-Bellot E. Guillemet E. Baudin-Baillieu A. Gaumer S. Komar A.A. Cullin C. Characterization of the interaction domains of Ure2p, a prion-like protein of yeast Biochem. J. 338 1999 403 407
53. Gajdusek D.C. Unconventional viruses and the origin and disappearance of Kuru Science 197 1977 943 960
54. Glover J.R. Kowal A.S. Shirmer E.C. Patino M.M. Liu J.-J. Lindquist S. Self-seeded fibers formed by Sup35, the protein determinant of [ PSI +], a heritable prion-like factor of S. cerevisiae Cell 89 1997 811 819
55. Griffith J.S. Self-replication and scrapie Nature 215 1967 1043 1044
56. Grimes G.W. Aufderheide K.J. Cellular Aspects of Pattern Formation: The Problem of Assembly 1991 Karger Basel
57. Grishok A. Pasquinelli A.E. Conte D. Li N. Parrish S. Ha I. Baillie D.L. Fire A. Ruvkun D. Mello C.C. Genes and mechanisms related to RNA interference requlate expression of the small temporal RNAs that control C. elegans developmental timing Cell 106 2001 23 34
58. Guerrier-Takada C. Gardiner K. Marsh T. Pace N. Altman S. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme Cell 35 1983 849 857
59. Hagemann A.T. Selker E.U. Control and function of DNA methylation in Neurospora crassa Russo V.E.A. Martienssen R.A. Riggs A.D. Epigenetic Mechanisms of Gene Regulation 1996 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY 335 344
60. Hardwick J.S. Kuruvilla F.G. Tong J.K. Shamji A.F. Schreiber S.L. Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the tor proteins Proc. Natl. Acad. Sci. USA 96 1999 14866 14870 [In Process Citation]
61. Hsiao K.K. Scott M. Foster D. Groth D.F. DeArmond S.J. Prusiner S.B. Spontaneous neurodegeneration in transgenic mice with mutant prion protein of Gerstmann-Straussler syndrome Science 250 1990 1587 1590
62. Jung G. Jones G. Wegrzyn R.D. Masison D.C. A role for cytosolic Hsp70 in yeast [PSI+] prion propagation and [PSI+] as a cellular stress Genetics 156 2000 559 570
63. Jung G. Masison D.C. Guanidine hydrochloride inhibits Hsp104 activity in vivo: A possible explanation for its effect in curing yeast prions Curr. Microbiol. 43 2001 7 10
64. King C.-Y. Tittmann P. Gross H. Gebert R. Aebi M. Wuthrich K. Prion-inducing domain 2–114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments Proc. Natl. Acad. Sci. USA 94 1997 6618 6622
65. Kochneva-Pervukhova N.V. Poznyakovski A.I. Smirnov V.N. Ter-Avanesyan M.D. C-terminal truncation of the Sup35 protein increases the frequency of de novo gneration of a prion-based [PSI+] determinant in Saccharmyces cerevisiae Curr. Genet. 34 1998 146 151
66. Kocisko D.A. Come J.H. Priola S.A. Chesebro B. Raymond G.J. Lansbury P.T. Caughey B. Cell-free formation of protease-resistant prion protein Nature 370 1994 471 474
67. Kocisko D.A. Priola S.A. Raymond G.J. Chesebro B. Landsbury P.T. Caughey B. Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier Proc. Natl. Acad. Sci. USA 92 1995 3923 3927
68. Krobitsch S. Lindquist S. Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins Proc. Natl. Acad. Sci. USA 97 2000 1589 1594
69. Kruger K. Grabowski P.J. Zaug A.J. Sands J. Gottschling D.E. Cech T.R. Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena Cell 31 1982 147 157
70. Kushnirov V.V. Kochneva-Pervukhova N.V. Cechenova M.B. Frolova N.S. Ter-Avanesyan M.D. Prion properties of the Sup35 protein of yeast Pichia methanolica EMBO J. 19 2000 324 331
71. Lacroute F. Non-Mendelian mutation allowing ureidosuccinic acid uptake in yeast J. Bacteriol. 106 1971 519 522
72. Leibowitz M.J. Wickner R.B. Pet18: A chromosomal gene required for cell growth and for the maintenance of mitochondrial DNA and the killer plasmid of yeast Mol. Gen. Genet. 165 1978 115 121
73. Li L. Lindquist S. Creating a protein-based element of inheritance Science 287 2000 661 664
74. Liebman S.W. Sherman F. Extrachromosomal [PSI+] determinant suppresses nonsense mutations in yeast J. Bacteriol. 139 1979 1068 1071
75. Liebman S.W. Stewart J.W. Sherman F. Serine substitutions caused by an ochre suppressor in yeast J. Mol. Biol. 94 1975 595 610
76. Liu J.J. Lindquist S. Oligopeptide-repeat expansions modulate “protein-only” inheritance in yeast Nature 400 1999 573 576
77. Lu Z. Cyr D.M. Protein folding activity of Hsp70 is modified differentially by the Hsp40 co-chaperones Sis1 and Ydj1 J. Biol. Chem. 273 1998 27824 27830
78. Lund P.M. Cox B.S. Reversion analysis of [psi-] mutations in Saccharomyces cerevisiae Genet. Res. 37 1981 173 182
79. Maddelein M.-L. Wickner R.B. Two Prion-Inducing Regions of Ure2p are Non-Overlapping Mol. Cell. Biol. 19 1999 4516 4524
80. Magasanik B. Regulation of nitrogen utilization Jones E.W. Pringle J.R. Broach J.R. The Molecular and Cellular Biology of the Yeast Saccharomyces vol. 2 1992 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY 283 317
81. Manson J.C. Jamieson E. Baybutt H. Tuzi N.L. Barron R. McConnell I. Somerville R. Ironside J. Will R. Sy M.-S. Melton D.W. Hope J. Bostock C. A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy EMBO J. 18 1999 6855 6864
82. Masison D.C. Maddelein M.-L. Wickner R.B. The prion model for [URE3] of yeast: Spontaneous generation and requirements for propagation Proc. Natl. Acad. Sci. USA 94 1997 12503 12508
83. Masison D.C. Wickner R.B. Prion-inducing domain of yeast Ure2p and protease resistance of Ure2p in prion-containing cells Science 270 1995 93 95
84. Matsuura A. Anraku Y. Characterization of the MKS1 gene, a new negative regulator of the ras-cyclic AMP pathway in Saccharomyces cerevisiae Mol. Gen. Genet. 238 1993 6 16
85. Matzke M. Matzke A.J. Kooter J.M. RNA guiding gene silencing Science 293 2001 1080 1083
86. Meacham G.C. Browne B.L. Zhang W. Kellermayer R. Bedwell D.M. Cyr D.M. Mutations in the yeast Hsp40 chaperone protein Ydj1 cause defects in Axl1 biogenesis and pro-a-factor processing J. Biol. Chem. 274 1999 34396 34402
87. Moriyama H. Edskes H.K. Wickner R.B. [URE3] prion propagation in Saccharomyces cerevisiae : Requirement for chaperone Hsp104 and curing by overexpressed chaperone Ydj1p Mol. Cell. Biol. 20 2000 8916 8922
88. Nelson R.J. Ziegelhoffer T. Nicolet C. Werner-Washburne M. Craig E.A. The translation machinery and 70 kd heat shock protein cooperate in protein synthesis Cell 71 1992 97 105
89. Newnam G.P.R.D. Wegrzyn S.L.L. Chernoff Y.O. Antagonistic interactions between yeast chaperones Hsp104 and Hsp70 in prion curing Mol. Cell. Biol. 19 1999 1325 1333
90. Novick A. Weiner M. Enzyme induction as an all-or-none phenomenon Proc. Natl. Acad. Sci. USA 43 1957 553 566
91. Oesch B. Westaway D. Walchli M. McKinley M.P. Kent S.B. Aebersold R. Barry R.A. Tempst P. Templow D.B. Hood L.E. Prusiner S.B. Weissmann C. A cellular gene encodes scrapie PrP 27–30 protein Cell 40 1985 735 746
92. Osherovich L.Z. Weissman J.S. Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [ PSI +] prion Cell 106 2001 183 194
93. Palmer E. Wilhelm J. Sherman F. Phenotypic suppression of nonsense mutants in yeast by aminoglycoside antibiotics Nature 277 1979 148 150
94. Parsell D.A. Kowal A.S. Singer M.A. Lindquist S. Protein disaggregation mediated by heat-shock protein Hsp104 Nature 372 1994 475 478
95. Patino M.M. Liu J.-J. Glover J.R. Lindquist S. Support for the prion hypothesis for inheritance of a phenotypic trait in yeast Science 273 1996 622 626
96. +] determinant is mediated by oligomerization of the SUP35 –encoded polypeptide chain release factor EMBO J. 15 1996 3127 3134
97. Paushkin S.V. Kushnirov V.V. Smirnov V.N. Ter-Avanesyan M.D. In vitro propagation of the prion-like state of yeast Sup35 protein Science 277 1997 381 383
98. Perrett S. Freeman S.J. Butler P.J.G. Fersht A.R. Equilibrium folding properties of the yeast prion protein determinant Ure2 J. Mol. Biol. 290 1999 331 345
99. Pfund C. Lopez-Hoyo N. Ziegelhoffer T. Schilke B.A. Lopez-Buesa P. Walter W.A. Wiedmann M. Craig E.A. The molecular chaperone Ssb from Saccharomyces cerevisiae is a component of the ribosome-nascent chain complex EMBO J. 17 1998 3981 3989
100. Prusiner S.B. Novel proteinaceous infectious particles cause scrapie Science 216 1982 136 144
101. Prusiner S.B. Prions Proc. Natl. Acad. Sci. USA 95 1998 13363 13383
102. Prusiner S.B. Prion Biology and Diseases 1999 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY
103. Prusiner S.B. Scott M. Foster D. Pan K.-M. Groth D. Mirenda C. Torchia M. Yang S.-L. Serban D. Carlson G.A. Hoppe P.C. Westaway D. DeArmond S.J. Transgenic studies implicate interactions between homologous PrP isoforms in scrapie prion replication Cell 63 1990 673 686
104. Rai R. Genbauffe F. Lea H.Z. Cooper T.G. Transcriptional regulation of the DAL5 gene in Saccharomyces cerevisiae J. Bacteriol. 169 1987 3521 3524
105. Rizet G. Les phenomenes de barrage chez Podospora anserina : Analyse genetique des barrages entre les souches s et S Rev. Cytol. Biol. Veg. 13 1952 51 92
106. Santoso A. Chien P. Osherovich L.Z. Weissman J.S. Molecular basis of a yeast prion species barrier Cell 100 2000 277 288
107. Saupe S.J. Molecular genetics of heterokaryon incompatibility in filamentous ascomycetes Microbiol. Mol. Biol. Rev. 64 2000 489 502
108. Schlumpberger M. Willie H. Baldwin M.A. Butler D.A. Herskowitz I. Prusiner S.B. The prion domain of yeast Ure2p induces autocatalytic formation of amyloid fibers by a recombinant fusion protein Protein. Sci. 9 2000 440 451
109. Singh A.C. Helms C. Sherman F. Mutation of the non-Mendelian suppressor [PSI] in yeast by hypertonic media Proc. Natl. Acad. Sci. USA 76 1979 1952 1956
110. Sipe J.D. Amyloidosis Annu. Rev. Biochem. 61 1992 947 975
111. Sondheimer N. Lindquist S. Rnq1: An epigenetic modifier of protein function in yeast Mol. Cell 5 2000 163 172
112. Sparrer H.E. Santoso A. Szoka F.C. Weissman J.S. Evidence for the prion hypothesis: Induction of the yeast [PSI+] factor by in vitro-converted Sup35 protein Science 289 2000 595 599
113. Speransky V. Taylor K.L. Edskes H.K. Wickner R.B. Steven A. Prion filament networks in [URE3] cells of Saccharomyces cerevisiae J. Cell Biol. 153 2001 1327 1335
114. Stansfield I. Jones K.M. Kushnirov V.V. Dagkesamanskaya A.R. Poznyakovski A.I. Paushkin S.V. Nierras C.R. Cox B.S. Ter-Avanesyan M.D. Tuite M.F. The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae EMBO J. 14 1995 4365 4373
115. Stone D.E. Craig E.A. Self-regulation of 70 kilodalton heat shock proteins in Saccharomyces cerevisiae Mol. Cell. Biol. 10 1990 1622 1632
116. Talloczy Z. Mazar R. Georgopoulos D.E. Ramos F. Leibowitz M.J. The [KIL-d] element specifically regulates viral gene expression in yeast Genetics 155 2000 601 609
117. Talloczy Z. Menon S. Neigeborn L. Leibowitz M.J. The [KIL-d] cytoplasmid genetic element of yeast results in epigenetic regulation of viral M double-stranded RNA gene expression Genetics 150 1998 21 30
118. Tamm I. Eggers H.J. Specific inhibition of replication of animal viruses Science 142 1963 24 33
119. Taylor K.L. Cheng N. Williams R.W. Steven A.C. Wickner R.B. Prion domain initiation of amyloid formation in vitro from native Ure2p Science 283 1999 1339 1343
120. TerAvanesyan A. Dagkesamanskaya A.R. Kushnirov V.V. Smirnov V.N. The SUP35 omnipotent suppressor gene is involved in the maintenance of the non-Mendelian determinant [psi+] in the yeast Saccharomyces cerevisiae Genetics 137 1994 671 676
121. True H.L. Lindquist S.L. A yeast prion provides a mechanism for genetic variation and phenotypic diversity Nature 407 2000 477 483
122. Tuite M.F. Lund P.M. Futcher A.B. Dobson M.J. Cox B.S. McLaughlin C.S. Relationship of the [psi] factor with other plasmids of Saccharomyces cerevisiae Plasmid 8 1982 103 111
123. Tuite M.F. Mundy C.R. Cox B.S. Agents that cause a high frequency of genetic change from [ psi +] to [ psi -] in Saccharomyces cerevisiae Genetics 98 1981 691 711
124. Turcq B. Deleu C. Denayrolles M. Begueret J. Two allelic genes responsible for vegetative incompatibility in the fungus Podospora anserina are not essential for cell viability Mol. Gen. Genet. 288 1991 265 269
125. Turoscy V. Cooper T.G. Ureidosuccinate is transported by the allantoate transport system in Saccharomyces cerevisiae J. Bacteriol. 169 1987 2598 2600
126. Umland T.C. Taylor K.L. Rhee S. Wickner R.B. Davies D.R. The crystal structure of the nitrogen catabolite regulatory fragment of the yeast prion protein Ure2p Proc. Natl. Acad. Sci. USA 98 2001 1459 1464
127. serUCA Nucleic Acids Res. 9 1981 3077 3088
128. Westaway D. DeArmond S.J. Cayetano-Canlas J. Groth D. Foster D. Yang S.-L. Torchia M. Carlson G.A. Prusiner S.B. Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins Cell 76 1994 117 129
129. Wickner R.B. Mutants of the killer plasmid of Saccharomyces cerevisiae dependent on chromosomal diploidy for expression and maintenance Genetics 82 1976 273 285
130. Wickner R.B. Evidence for a prion analog in S. cerevisiae: The [URE3] non-Mendelian genetic element as an altered URE2 protein Science 264 1994 566 569
131. Wickner R.B. Viruses of yeasts, fungi and parasitic microorganisms Fields B.N. Knipe D.M. Howley P.M. Fields Virology vol. 1 1996 Raven New York 557 585
132. Zhouravleva G. Frolova L. LeGoff X. LeGuellec R. Inge-Vectomov S. Kisselev L. Philippe M. Termination of translation in eukaryotes is governed by two interacting polypeptide chain release factors, eRF1 and eRF3 EMBO J. 14 1995 4065 4072