Mutational analysis of the [Het-s] prion analog of Podospora anserina: A short N-terminal peptide allows prion propagation

Genetics

Volumn 153, Issue 4, 1999, Pages 1629-1640

  Coustou, Virginie ^a   Deleu, Carole ^b   Saupe, Sven J ^a,c   Bégueret, Joël ^a  

^a Institut de Biochimie et Genetique Cellulaires   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; PRION PROTEIN;

ALLELISM; AMINO TERMINAL SEQUENCE; ARTICLE; CELL DEATH; CELL GROWTH; DELETION MUTANT; GENE EXPRESSION; GENE LOCUS; GENE MUTATION; HETEROKARYON; NONHUMAN; PHENOTYPE; PODOSPORA ANSERINA; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; ASCOMYCOTA; BASE SEQUENCE; DNA PRIMERS; MUTAGENESIS; PRIONS;

EID: 0032711226     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. BEGUERET, J., B. TURCQ and C. CLAVE, 1994 Vegetative incompatibility in filamentous fungi: het genes begin to talk. Trends Genet. 10: 441-446.
2. BELCOUR, L., 1976 Loss of a cytoplasmic determinant through formation of protoplasts in Podospora. Neurospora Newsl. 23: 26-27.
3. BELCOUR, L., and J. BERNET, 1969 Sur la mise en évidence d'un gène dont la mutation supprime spécifiquement certaines manifestations d'incompatibilité chez le Podospora anserina. C. R. Acad. Sci. Paris 269: 712-714.
4. BERGES, T., and C. BARREAU, 1989 Heat-shock at an elevated temperature improves transformation efficiency of protoplasts from Podospora anserina. J. Gen. Microbiol. 135: 601-604.
5. BLABER, M., X. ZHANG and B. W. MATTHEWS, 1993 Structural basis of amino acid α helix propensity. Science 260: 1637-1640.
6. CARROL, A. M., J. A. SWEIGARD and B. VALENT-CENTRAL, 1994 Improved vectors for selecting resistance to hygromycin. Fungal Genet. Newsl. 41: 22.
7. CHERNOFF, Y. O., S. L. LINDQUIST, B. ONO, S. G. INGE-VECHHTOMOV and S. W. LIEBMAN, 1995 Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]. Science 268: 880-884.
8. COUSTOU, V., C. DELEU, S. SAUPE and J. BEGUERET, 1997 The protein product of the het-s heterokaryon incompatibility gene of the fungus Podospora anserina behaves as a prion analog. Proc. Natl. Acad. Sci. USA 64: 9773-9778.
9. DELEU, C., C. CLAVE and J. BEGUERET, 1993 A single amino acid difference is sufficient to elicit vegetative incompatibility in the fungus Podospora anserina. Genetics 135: 45-52.
10. ESSER, K., 1974 Podospora anserina, pp. 531-551 in Handbook of Genetics, edited by R. C. KING. Plenum Press, New -York.
11. FRISHMAN, D., and P. ARGOS, 1996 Incorporation of non-local interactions in protein secondary structure prediction from the amino acid sequence. Protein Eng. 9: 133-142.
12. GLOVER, J. R., A. S. KOWAL, E. C. SCHIRMER, M. M. PATINO, J. LIU et al., 1997 Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae. Cell 89: 811-819.
13. GRIFFITHS, A. J. F., 1982 Null mutants of the A and a mating type of Neurospora crassa. Can. J. Genet. Cytol. 24: 167-176.
14. HORWICH, A. L., and J. S. WEISSMAN, 1997 Deadly conformations-protein misfolding in prion disease. Cell 89: 499-510.
15. KING, C., P. TITTMANN, H. GROSS, R. GEBERT, M. AEBI et al., 1997 Prion-inducing domain 2-114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments. Proc. Natl. Acad. Sci. USA 94: 6618-6622.
16. KUNZ, B. A., M. K. PIERCE, J. R. MIS and C. N. GIROUX, 1987 DNA sequence analysis of the mutational specificity of u.v. light in SUP4-o gene of yeast. Mutagenesis 2: 445-453.
17. KUSHNIROV, V. V., and M. D. TER-AVANESYAN, 1998 Structure and replication of yeast prions. Cell 94: 13-16.
18. LECELLIER, G., and P. SILAR, 1994 Rapid methods for nucleic acids extraction from Petri dish-grown mycelia. Curr. Genet. 25: 122-123.
19. LINDQUIST, S., 1997 Mad cows meet psi-chotic yeast: the expansion of the prion hypothesis. Cell 89: 495-498.
20. MADDELEIN, M. L., and R. B. WICKNER, 1999 Two prion-inducing of Ure2p are nonoverlapping. Mol. Cell. Biol. 19: 4516-4524.
21. MASISON, D. C., and R. WICKNER, 1995 Prion-inducing domain of yeast Ure2p and protease resistance of Ure2p in prion-containing cells. Science 270: 93-95.
22. MASISON, D. C., M. L. MADDELEIN and R. WICKNER, 1997 The prion model for [URE3] of yeast: spontaneous generation and requirements for propagation. Proc. Natl. Acad. Sci. USA 94: 12503-12508.
23. NEWMEYER, D., 1970 A suppressor of heterokaryon-incompatibility associated with mating type in Neurospora crassa. Can. J. Genet. Cytol. 12: 9914-9926.
24. PACE, C. N., and J. M. SCHOLTZ, 1998 A helix propensity scale based on experimental studies of peptides and proteins. Biophys. J. 75: 422-427.
25. PATINO, M. M., J. LIU, J. R. GLOVER and S. LINDQUIST, 1996 Support for the prion hypothesis for inheritance of a phenotypic trait in yeast. Science 273: 622-626.
26. PAUSHKIN, S. V., V. V. KUSHNIROV, V. N. SMIRNOV and M. D. TER-AVANESYAN, 1996 Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor. EMBO J. 15: 3127-3134.
27. PAUSHKIN, S. V., V. V. KUSHNIROV, V. N. SMIRNOV and M. D. TER-AVANESYAN, 1997 In vitro propagation of the prion-like state of yeast Sup35 protein. Science 18: 381-383.
28. PRUSINER, S. B., 1998 Prions. Proc. Natl. Acad. Sci. USA 95: 13363-13383.
29. PUNT, P. J., M. A. DINGEMANSE, B. J. M. JACOBS-MEIJSING, P. H. POUWELS and C. A. M. J. J. VAN DEN HONDEL, 1988 Isolation and characterization of the glyceraldehyde-3-phosphate dehydrogenase gene of Aspergillus nidulans. Gene 69: 49-57.
30. RIZET, G., 1952 Les phénomènes de barrage chez Podospora anserina, I. Analyse génétique des barrages entre souches S et s. Rev. Cytol. Biol. Veg. 13: 51-93.
31. SAUPE, S., L. STENBERG, K. T. SHIU, A. J. F. GRIFFITHS and N. L. GLASS, 1996 The molecular nature of mutations in the mt A-1 gene of the Neurospora crassa A idiomorph and their relation to mating-type function. Mol. Gen. Genet. 250: 115-122.
32. SMITH, M. L., C. J. YANG, R. L. METZENBERG and N. L. GLASS, 1996 Escape from het-6 incompatibility in Neurospora crassa partial diploids involves preferential deletion within the ectopic segment. Genetics 144: 523-531.
33. TAYLOR, K. L., N. CHENG, R. W. WILLIAMS, A. C. STEVEN and R. B. WICKNER, 1999 Prion domain initiation of amyloid formation in vitro from native ure2p. Science 283: 1339-1343.
34. TER-AVANESYAN, M. D., A. R. DAGKESAMANKAYA, V. V. KUSHNIROV and V. N. SMIRNOV, 1994 The SUP35 omnipotent suppressor gene is involved in the maintenance of the non-mendelian determinant [psi+] in the yeast Saccharomyces cerevisiae. Genetics 137: 671-676.
35. THUAL, C., A. A. KOMAR, L. BOUSSET, E. FERNANDEZ-BELLOT, C. CULLIN et al., 1999 Structural characterization of the Saccharomyces cerevisiae prion-like protein Ure2. J. Biol. Chem. 274: 13666-13674.
36. TURCQ, B., C. DELEU, M. DENAYROLLES and J. BEGUERET, 1991 Two allelic genes responsible for vegetative incompatibility in the fungus Podospora anserina are not essential for cell viability. Mol. Gen. Genet. 288: 265-269.
37. WICKNER, R., 1994 [URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae. Science 264: 566-569.