Enhancing the anticancer efficacy of camptothecin using biotinylated poly(ethyleneglycol) conjugates in sensitive and multidrug-resistant human ovarian carcinoma cells

Cancer Chemotherapy and Pharmacology

Volumn 50, Issue 2, 2002, Pages 143-150

  Minko, Tamara ^a,b,c,e,f   Paranjpe, Pankaj V ^a,b,c,e,f   Qiu, Bo ^a,b,c,e,f   Lalloo, Anita ^a,b,c,e,f   Won, Roney ^a,b,c,e,f   Stein, Stanley ^a,b,c,d,e,f   Sinko, Patrick J ^a,b,c,e,f  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^c NJ USA   (United States)

^d RUTGERS UNIVERSITY   (United States)

^e RUTGERS UNIVERSITY   (United States)

^f RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Camptothecin; Human ovarian carcinoma; Poly(ethyleneglycol) biotin conjugates; Sodium dependent multivitamin transporter

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CAMPTOTHECIN; CASPASE 3; CASPASE 9; DNA TOPOISOMERASE; MACROGOL; PROTEIN BCL 2;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOTINYLATION; CANCER CELL; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELLULAR IMMUNITY; CONCENTRATION RESPONSE; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DOWN REGULATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SENSITIVITY; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; EVALUATION; GENE OVEREXPRESSION; GENETIC CODE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MULTIDRUG RESISTANCE; OVARY CARCINOMA; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BIOLOGICAL TRANSPORT; BIOTINYLATION; CAMPTOTHECIN; CARRIER PROTEINS; CASPASES; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BCL-2; HUMANS; MEMBRANE GLYCOPROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; POLYETHYLENE GLYCOLS; PROTEIN BIOSYNTHESIS; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; SOLUBILITY; SYMPORTERS; TUMOR CELLS, CULTURED;

EID: 0036354863     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-002-0463-1     Document Type: Article

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