메뉴 건너뛰기




Volumn 132, Issue 8, 2000, Pages 661-668

The Lyme disease vaccine: Conception, development, and implementation

Author keywords

[No Author keywords available]

Indexed keywords

LYME DISEASE VACCINE; OUTER MEMBRANE PROTEIN;

EID: 0034681975     PISSN: 00034819     EISSN: None     Source Type: Journal    
DOI: 10.7326/0003-4819-132-8-200004180-00009     Document Type: Review
Times cited : (50)

References (74)
  • 2
  • 6
    • 0029959724 scopus 로고    scopus 로고
    • The recombinant outer surface protein A (lipOspA) of Borrelia burgdorferi: A Lyme disease vaccine
    • Wallich R, Kramer MD, Simon MM. The recombinant outer surface protein A (lipOspA) of Borrelia burgdorferi: a Lyme disease vaccine. Infection. 1996; 24:396-7.
    • (1996) Infection , vol.24 , pp. 396-397
    • Wallich, R.1    Kramer, M.D.2    Simon, M.M.3
  • 7
    • 0031729329 scopus 로고    scopus 로고
    • A cost-of-illness study of Lyme disease in the United States
    • Maes E, Lecomte P, Ray N. A cost-of-illness study of Lyme disease in the United States. Clin Ther. 1998;20:993-1008.
    • (1998) Clin Ther. , vol.20 , pp. 993-1008
    • Maes, E.1    Lecomte, P.2    Ray, N.3
  • 8
    • 0029963104 scopus 로고    scopus 로고
    • Three species of borrelia burgdorferi sensu lato (b. Burgdorieri sensu stricto, b. Afzelii, and b. Garinii) identified from cerebrospinal fluid isolates by pulsed-field gel electrophoresis and PCR
    • Busch U, Hizo-Teufel C, Boehmer R, Fingerle V, Nitschko H, Wilske B, et al. Three species of Borrelia burgdorferi sensu lato (B. burgdorieri sensu stricto, B. afzelii, and B. garinii) identified from cerebrospinal fluid isolates by pulsed-field gel electrophoresis and PCR. J Clin Microbiol. 1996;34:1072-8.
    • (1996) J Clin Microbiol. , vol.34 , pp. 1072-1078
    • Busch, U.1    Hizo-Teufel, C.2    Boehmer, R.3    Fingerle, V.4    Nitschko, H.5    Wilske, B.6
  • 9
    • 0030034399 scopus 로고    scopus 로고
    • Identification of an uncultivable borrelia species in the hard tick amblyomma americanum: Possible agent of a Lyme disease-like illness
    • Barbour AG, Maupin GO, Teltow GJ, Carter G, Piesman J. Identification of an uncultivable Borrelia species in the hard tick Amblyomma americanum: possible agent of a Lyme disease-like illness. J Infect Dis. 1996;173:403-9.
    • (1996) J Infect Dis. , vol.173 , pp. 403-409
    • Barbour, A.G.1    Maupin, G.O.2    Teltow, G.J.3    Carter, G.4    Piesman, J.5
  • 10
    • 0025896014 scopus 로고
    • Perspective on the development of vaccines against Lyme disease
    • Edelman R. Perspective on the development of vaccines against Lyme disease. Vaccine. 1991;9:531-2.
    • (1991) Vaccine , vol.9 , pp. 531-532
    • Edelman, R.1
  • 11
    • 0024676260 scopus 로고
    • National surveillance of Lyme disease, 1987-1988
    • Tsai TF, Bailey RE, Moore PS. National surveillance of Lyme disease, 1987-1988. Conn Med. 1989;53:324-6.
    • (1989) Conn Med. , vol.53 , pp. 324-326
    • Tsai, T.F.1    Bailey, R.E.2    Moore, P.S.3
  • 12
    • 0032574936 scopus 로고    scopus 로고
    • Underreporting of Lyme disease [Letter]
    • Young JD. Underreporting of Lyme disease [Letter]. N Engl J Med. 1998;338: 1629.
    • (1998) N Engl J Med. , vol.338 , pp. 1629
    • Young, J.D.1
  • 15
    • 0030218954 scopus 로고    scopus 로고
    • Immunity to Lyme disease: Protection, pathology and persistence
    • Seiler KP, Weiss JJ. Immunity to Lyme disease: protection, pathology and persistence. Curr Opin Immunol. 1996;8:503-9.
    • (1996) Curr Opin Immunol. , vol.8 , pp. 503-509
    • Seiler, Kp.1    Weiss, J.J.2
  • 16
    • 0027288183 scopus 로고
    • Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi
    • Kalish RA, Leong JM, Steere AC. Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi. Infect Immun. 1993;61:2774-9.
    • (1993) Infect Immun. , vol.61 , pp. 2774-2779
    • Kalish, R.A.1    Leong, J.M.2    Steere, A.C.3
  • 17
    • 0028114190 scopus 로고
    • The T helper cell response in Lyme arthritis: Differential recognition of Borrelia burgdorferi outer surface protein A in patients with treatment-resistant or treatment-responsive Lyme arthritis
    • Lengl-Janssen B, Strauss AF, Steere AC, Kamradt T, The T helper cell response in Lyme arthritis: differential recognition of Borrelia burgdorferi outer surface protein A in patients with treatment-resistant or treatment-responsive Lyme arthritis. J Exp Med. 1994;180:2069-78.
    • (1994) J Exp Med. , vol.180 , pp. 2069-2078
    • Lengl-Janssen, B.1    Strauss, A.F.2    Steere, A.C.3    Kamradt, T.4
  • 18
    • 0343863944 scopus 로고
    • Southern Connecticut Department of Health. Connecticut Epidemiology
    • Lyme disease: Connecticut. Southern Connecticut Department of Health. Connecticut Epidemiology. 1995;15:13-6.
    • (1995) Lyme Disease: Connecticut , vol.15 , pp. 13-16
  • 20
    • 0029917502 scopus 로고    scopus 로고
    • Increased cerebrospinal fluid levels of glial fibrillary acidic protein (GFAp) in Lyme neuroborreliosis
    • Dotevall L, Rosengren LE, Hagberg L. Increased cerebrospinal fluid levels of glial fibrillary acidic protein (GFAp) in Lyme neuroborreliosis. Infection. 1996;24:125-9.
    • (1996) Infection , vol.24 , pp. 125-129
    • Dotevall, L.1    Rosengren, L.E.2    Hagberg, L.3
  • 23
    • 0025242171 scopus 로고
    • Amoxicillin plus probenecid versus doxycycline for treatment of erythema migrans borreliosis
    • Dattwyler RJ, Volkman DJ, Conaty SM, Platkin SP, Luft BJ. Amoxicillin plus probenecid versus doxycycline for treatment of erythema migrans borreliosis. Lancet. 1990;336:1404-6.
    • (1990) Lancet , vol.336 , pp. 1404-1406
    • Dattwyler, R.J.1    Volkman, D.J.2    Conaty, S.M.3    Platkin, S.P.4    Luft, B.J.5
  • 26
    • 0031917278 scopus 로고    scopus 로고
    • Borreliacidal factor in the blood of the western fence lizard (Sceloporus occidentalis)
    • Lane RS, Quistad GB. Borreliacidal factor in the blood of the western fence lizard (Sceloporus occidentalis). J Parasitol. 1998;84:29-34.
    • (1998) J Parasitol , vol.84 , pp. 29-34
    • Lane, R.S.1    Quistad, G.B.2
  • 29
    • 0022479177 scopus 로고
    • Passive immunization of hamsters against experimental infection with the Lyme disease spirochete
    • Johnson RC, Kodner C, Russell M. Passive immunization of hamsters against experimental infection with the Lyme disease spirochete. Infect Immun. 1986;53:713-4.
    • (1986) Infect Immun. , vol.53 , pp. 713-714
    • Johnson, R.C.1    Kodner, C.2    Russell, M.3
  • 30
    • 0023025241 scopus 로고
    • Active immunization of hamsters against experimental infection with Borrelia burgdorferi
    • Johnson RC, Kodner C, Russell M. Active immunization of hamsters against experimental infection with Borrelia burgdorferi. Infect Immun. 1986; 54:897-8.
    • (1986) Infect Immun. , vol.54 , pp. 897-898
    • Johnson, R.C.1    Kodner, C.2    Russell, M.3
  • 33
    • 0027230563 scopus 로고
    • Cross-reactivity between Borrelia burgdorferi flagellin and a human axonal 64,000 molecular weight protein
    • Sigal LH. Cross-reactivity between Borrelia burgdorferi flagellin and a human axonal 64,000 molecular weight protein. J Infect Dis. 1993;167:1372-8.
    • (1993) J Infect Dis. , vol.167 , pp. 1372-1378
    • Sigal, L.H.1
  • 34
    • 0024785684 scopus 로고
    • Molecular mimicry and lyme borreliosis: A shared antigenic determinant between Borrelia burgdorferi and human tissue
    • Aberer E, Brunner C, Suchanek G, Klade H, Barbour A, Stanek G, et al. Molecular mimicry and Lyme borreliosis: a shared antigenic determinant between Borrelia burgdorferi and human tissue. Ann Neurol. 1989;26:732-7.
    • (1989) Ann Neurol. , vol.26 , pp. 732-737
    • Aberer, E.1    Brunner, C.2    Suchanek, G.3    Klade, H.4    Barbour, A.5    Stanek, G.6
  • 35
    • 0024362494 scopus 로고
    • Lyme disease
    • Steere AC. Lyme disease. N Engl J Med. 1989;321:586-96.
    • (1989) N Engl J Med. , vol.321 , pp. 586-596
    • Steere, A.C.1
  • 36
    • 0032061808 scopus 로고    scopus 로고
    • NMR studies of borrelia burgdorferi OspA, a 28kDa protein containing a single-layer beta-sheet
    • Pham TN, Koide S. NMR studies of Borrelia burgdorferi OspA, a 28kDa protein containing a single-layer beta-sheet. J Biomol NMR. 1998;11:407-14.
    • (1998) J Biomol NMR , vol.11 , pp. 407-414
    • Pham, T.N.1    Koide, S.2
  • 37
    • 0022999139 scopus 로고
    • Antigens of Borrelia burgdorferi recognized during Lyme disease: Appearance of a new immunoglobulin M response and expansion of the immunoglobulin G response late in the illness
    • Craft JE, Fischer DK, Shimamoto GT, Steere AC. Antigens of Borrelia burgdorferi recognized during Lyme disease: appearance of a new immunoglobulin M response and expansion of the immunoglobulin G response late in the illness. J Clin Invest. 1986;78:934-9.
    • (1986) J Clin Invest. , vol.78 , pp. 934-939
    • Craft, J.E.1    Fischer, D.K.2    Shimamoto, G.T.3    Steere, A.C.4
  • 39
    • 0025734145 scopus 로고
    • Kinetics of Borrelia burgdorferi dissemination and evolution of disease after intradermal inoculation of mice
    • Barthold SW, Persing DH, Armstrong AL, Peeples RA. Kinetics of Borrelia burgdorferi dissemination and evolution of disease after intradermal inoculation of mice. Am J Pathol. 1991;139:263-73.
    • (1991) Am J Pathol. , vol.139 , pp. 263-273
    • Barthold, S.W.1    Persing, D.H.2    Armstrong, A.L.3    Peeples, R.A.4
  • 40
    • 0026073406 scopus 로고
    • Lyme borreliosis: Host responses to Borrelia burgdorferi
    • Szczepanski A, Benach JL. Lyme borreliosis: host responses to Borrelia burgdorferi. Microbiol Rev. 1991;55:21-34.
    • (1991) Microbiol Rev. , vol.55 , pp. 21-34
    • Szczepanski, A.1    Benach, J.L.2
  • 41
    • 0028131929 scopus 로고
    • Borrelia burgdorferi antigens that are targeted by antibody-dependent, complement-mediated killing in the rhesus monkey
    • Aydintug MK, Gu Y, Philipp MT. Borrelia burgdorferi antigens that are targeted by antibody-dependent, complement-mediated killing in the rhesus monkey. Infect Immun. 1994;62:4929-37.
    • (1994) Infect Immun. , vol.62 , pp. 4929-4937
    • Aydintug, M.K.1    Gu, Y.2    Philipp, M.T.3
  • 42
    • 0023832955 scopus 로고
    • Immunoblot analysis of immunoglobulin G response to the Lyme disease agent (Borrelia burgdorferi) in experimentally and naturally infected dogs
    • Greene RT, Walker RL, Nicholson WL, Heidner HW, Levine JF, Burgess EC, et al. Immunoblot analysis of immunoglobulin G response to the Lyme disease agent (Borrelia burgdorferi) in experimentally and naturally infected dogs. J Clin Microbiol. 1988;26:648-53.
    • (1988) J Clin Microbiol. , vol.26 , pp. 648-653
    • Greene, R.T.1    Walker, R.L.2    Nicholson, W.L.3    Heidner, H.W.4    Levine, J.F.5    Burgess, E.C.6
  • 43
    • 0027478543 scopus 로고
    • Mode of inoculation of lhe Lyme disease agent Borrelia burgdorferi influences infection and immune responses in inbred strains of mice
    • Gern L, Schaible UE, Simon MM. Mode of inoculation of lhe Lyme disease agent Borrelia burgdorferi influences infection and immune responses in inbred strains of mice. J Infect Dis. 1993;167:971-5.
    • (1993) J Infect Dis. , vol.167 , pp. 971-975
    • Gern, L.1    Schaible, U.E.2    Simon, M.M.3
  • 44
    • 0026446362 scopus 로고
    • The hamster immune response to tick-transmitted Borrelia burgdorferi differs from the response to needle-inoculated, cultured organisms
    • Roehrig JT, Piesman J, Hunt AR, Keen MG, Happ CM, Johnson BJ. The hamster immune response to tick-transmitted Borrelia burgdorferi differs from the response to needle-inoculated, cultured organisms. J Immunol. 1992;149: 3648-53.
    • (1992) J Immunol. , vol.149 , pp. 3648-3653
    • Roehrig, J.T.1    Piesman, J.2    Hunt, A.R.3    Keen, M.G.4    Happ, C.M.5    Johnson, B.J.6
  • 45
    • 0029036568 scopus 로고
    • Circumvention of outer surface protein A immunity by host-adapted Borrelia burgdorferi
    • Barthold SW, Fikrig E, Bockenstedt LK, Persing DH. Circumvention of outer surface protein A immunity by host-adapted Borrelia burgdorferi. Infect Immun. 1995;63:2255-61.
    • (1995) Infect Immun. , vol.63 , pp. 2255-2261
    • Barthold, S.W.1    Fikrig, E.2    Bockenstedt, L.K.3    Persing, D.H.4
  • 47
    • 0030025949 scopus 로고
    • Borrelia burgdorferi OspA is an arthropod-specific transmission blocking Lyme disease vaccine
    • de Silva AM, Telford SR 3d, Brunet LR, Barthold SW, Fikrig E. Borrelia burgdorferi OspA is an arthropod-specific transmission blocking Lyme disease vaccine. J Exp Med. 1995;183:271-5.
    • (1995) J Exp Med. , vol.183 , pp. 271-275
    • De Silva, A.M.1    Telford S.R. III2    Brunet, L.R.3    Barthold, S.W.4    Fikrig, E.5
  • 49
    • 0025202254 scopus 로고
    • Protection of mice against the Lyme disease agent by immunizing with recombinant OsaA
    • Fikrig E, Barthold SW, Kantor FS, Flavell RA. Protection of mice against the Lyme disease agent by immunizing with recombinant OsaA. Science. 1990;250:553-6.
    • (1990) Science , vol.250 , pp. 553-556
    • Fikrig, E.1    Barthold, S.W.2    Kantor, F.S.3    Flavell, R.A.4
  • 50
    • 0026507230 scopus 로고
    • Long-term protection of mice from Lyme disease by vaccination with OspA
    • Fikrig E, Barthold SW, Kantor FS, Flavell RA. Long-term protection of mice from Lyme disease by vaccination with OspA. Infect Immun. 1992;60: 773-7.
    • (1992) Infect Immun. , vol.60 , pp. 773-777
    • Fikrig, E.1    Barthold, S.W.2    Kantor, F.S.3    Flavell, R.A.4
  • 51
    • 0025333897 scopus 로고
    • Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice
    • Schaible UE, Kramer MD, Eickmann K, Modolell M, Museteanu C, Simon MM. Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice. Proc Nat Acad Sci U S A. 1990;87:3768-72.
    • (1990) Proc Nat Acad Sci U S A , vol.87 , pp. 3768-3772
    • Schaible, U.E.1    Kramer, M.D.2    Eickmann, K.3    Modolell, M.4    Museteanu C, S.M.M.5
  • 52
    • 0029053627 scopus 로고
    • Abilities of OspA proteins from different seroprotective groups of Borrelia burgdorferi to protect hamsters from infection
    • Lovrich SD, Callister SM, DuChateau BK, Lim LC, Winfrey J, Day SP, et al. Abilities of OspA proteins from different seroprotective groups of Borrelia burgdorferi to protect hamsters from infection. Infect Immun. 1995;63:2113-9.
    • (1995) Infect Immun. , vol.63 , pp. 2113-2119
    • Lovrich, S.D.1    Callister, S.M.2    DuChateau, B.K.3    Lim, L.C.4    Winfrey, J.5    Day, S.P.6
  • 54
    • 0030733650 scopus 로고    scopus 로고
    • The outer surface protein A (OspA) vaccine against Lyme disease: Efficacy in the rhesus monkey
    • Philipp MT, Lobet Y, Bohm RP, Roberts ED, Dennis VA, Gu Y, et al. The outer surface protein A (OspA) vaccine against Lyme disease: efficacy in the rhesus monkey. Vaccine. 1997;15 1872-87.
    • (1997) Vaccine , pp. 151872-151887
    • Philipp, M.T.1    Lobet, Y.2    Bohm, R.P.3    Roberts, E.D.4    Dennis, V.A.5    Gu, Y.6
  • 55
    • 0025976063 scopus 로고
    • Antiborrelial activity of serum from rats injected with the Lyme disease spirochete
    • Pavia CJ, Kissel V, Bittker S, Cabello F, Levine S. Antiborrelial activity of serum from rats injected with the Lyme disease spirochete. J Infect Dis. 1991; 163:656-9.
    • (1991) J Infect Dis. , vol.163 , pp. 656-659
    • Pavia, C.J.1    Kissel, V.2    Bittker, S.3    Cabello, F.4    Levine, S.5
  • 56
    • 0028086479 scopus 로고
    • Fc-and non-Fc-mediated phagocytosis of Borrelia burgdorferi by macrophages
    • Montgomery RR, Nathanson MH, Malawista SE. Fc-and non-Fc-mediated phagocytosis of Borrelia burgdorferi by macrophages. J Infect Dis. 1994; 170:890-3.
    • (1994) J Infect Dis. , vol.170 , pp. 890-893
    • Montgomery, R.R.1    Nathanson, M.H.2    Malawista, S.E.3
  • 61
    • 0028236921 scopus 로고
    • Safety and immunogenicity of a recombinant outer surface protein A Lyme vaccine
    • Keller D, Koster FT, Marks DH, Hosbach P, Erdile LF, Mays JP. Safety and immunogenicity of a recombinant outer surface protein A Lyme vaccine. JAMA. 1994;271:1764-8.
    • (1994) JAMA , vol.271 , pp. 1764-1768
    • Keller, D.1    Koster, F.T.2    Marks, D.H.3    Hosbach, P.4    Erdile, L.F.5    Mays, J.P.6
  • 62
    • 0028787662 scopus 로고
    • Safety and immunogenicity of an outer surface protein A vaccine in subjects with previous Lyme disease
    • Schoen RT, Meurice F, Brunei CM, Cretella S, Krause DS, Craft JE, et al. Safety and immunogenicity of an outer surface protein A vaccine in subjects with previous Lyme disease. J Infect Dis. 1995;172:1324-9.
    • (1995) J Infect Dis. , vol.172 , pp. 1324-1329
    • Schoen, R.T.1    Meurice, F.2    Brunei, C.M.3    Cretella, S.4    Krause, D.S.5    Craft, J.E.6
  • 65
    • 0032560790 scopus 로고    scopus 로고
    • A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease
    • Sigal LM, Zahradnik JM, Lavin P, Patella SJ, Bryant G, Haselby R, et al. A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease. N Engl J Med. 1998;339:216-22.
    • (1998) N Engl J Med. , vol.339 , pp. 216-222
    • Sigal, L.M.1    Zahradnik, J.M.2    Lavin, P.3    Patella, S.J.4    Bryant, G.5    Haselby, R.6
  • 68
    • 0033055807 scopus 로고    scopus 로고
    • Alternative vaccination schedules (0, 1, and 6 months versus 0, 1, and 12 months) for a recombinant OspA Lyme disease vaccine
    • Van Hoecke C, Lebacq E, Beran J, Parenti D. Alternative vaccination schedules (0, 1, and 6 months versus 0, 1, and 12 months) for a recombinant OspA Lyme disease vaccine. Clin Infect Dis. 1999;28:1260-4.
    • (1999) Clin Infect Dis. , vol.28 , pp. 1260-1264
    • Van Hoecke, C.1    Lebacq, E.2    Beran, J.3    Parenti, D.4
  • 70
    • 0031789703 scopus 로고    scopus 로고
    • Heterogeneity of borrelia burgdorferi sensu lato demonstrated by an ospA-type-specific pcr in synovial fluid from patients with lyme arthritis
    • (Berl)
    • Vasiliu V, Herzer P, Rossler D, Lehnert G, Wilske B. Heterogeneity of Borrelia burgdorferi sensu lato demonstrated by an ospA-type-specific PCR in synovial fluid from patients with Lyme arthritis. Med Microbiol Immunol (Berl). 1998;187:97-102.
    • (1998) Med Microbiol Immunol , vol.187 , pp. 97-102
    • Vasiliu, V.1    Herzer, P.2    Rossler, D.3    Lehnert, G.4    Wilske, B.5
  • 71
    • 0026608004 scopus 로고
    • Borrelia burgdorferi strain 25015: Characterization of outer surface protein A and vaccination against infection
    • Fikrig E, Barthold SW, Persing DH, Sun X, Kantor FS, Flavell RA. Borrelia burgdorferi strain 25015: characterization of outer surface protein A and vaccination against infection. J Immunol. 1992;148:2256-60.
    • (1992) J Immunol. , vol.148 , pp. 2256-2260
    • Fikrig, E.1    Barthold, S.W.2    Persing, D.H.3    Sun, X.4    Kantor, F.S.5    Flavell, R.A.6
  • 72
    • 34548520182 scopus 로고    scopus 로고
    • Recommendations for the use of Lyme disease vaccine. Recommendations of the advisory committee on immunization practices (ACIP)
    • Recommendations for the use of Lyme disease vaccine. Recommendations of the Advisory Committee on Immunization Practices (ACIP) MMWR Morb Mortal WkIy Rep. 1999;48:1-17.
    • (1999) Mmwr Morb Mortal Wkiy Rep. , vol.48 , pp. 1-17
  • 73
    • 0343640806 scopus 로고    scopus 로고
    • Evaluation of an OspA Lyme disease vaccine in children aged 5-1 5 years [abstract]
    • Denver, CO
    • Beran J, Van Hoecke C, Boutriau D. Evaluation of an OspA Lyme disease vaccine in children aged 5-1 5 years [Abstract]. Denver, CO: Infectious Disease Soc of America; 1998:75.
    • Infectious Disease Soc of America , vol.1998 , pp. 75
    • Beran, J.1    Van Hoecke, C.2    Boutriau, D.3
  • 74
    • 0033605724 scopus 로고    scopus 로고
    • Lyme disease vaccine
    • Lyme disease vaccine. Med Lett Drugs Ther. 1999;41:29-30.
    • (1999) Med Lett Drugs Ther , vol.41 , pp. 29-30


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.