Memory CD8+ T cells undergo peripheral tolerance

Immunity

Volumn 17, Issue 1, 2002, Pages 73-81

  Kreuwel, Huub T C ^a   Aung, Sandra ^a   Silao, Cheryl ^a   Sherman, Linda A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNE DISEASE; CANCER; CONTROLLED STUDY; CROSS TOLERANCE; IMMUNOTHERAPY; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0036337603     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(02)00337-0     Document Type: Article

References (52)

1. T cell priming versus T cell tolerance induced by synthetic peptides
2. Peptide antigen treatment of naive and virus-immune mice: Antigen-specific tolerance versus immunopathology
3. + T cells
4. Control of neonatal tolerance to tissue antigens by peripheral T cell trafficking
5. Progression of autoimmune diabetes driven by avidity maturation of a T-cell population
6. Distinct kinetics of cytokine production and cytolysis in effector and memory T cells after viral infection
7. Systemic administration of agonist peptide blocks the progression of spontaneous CD8-mediated autoimmune diabetes in transgenic mice without bystander damage
8. Impact of negative selection of the T cell repertoire reactive to a self-peptide: A large fraction of T cell clones escapes clonal deletion
9. Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation
10. In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines
11. Functional differences between memory and naive CD8 T cells
12. Kinetic analysis of oral tolerance: Memory lymphocytes are refractory to oral tolerance
13. -) to TCR/CD8 signaling in response to antigen
14. CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo
15. Tracing and characterization of the low-avidity self-specific T cell repertoire
16. Following the development of a CD4 T cell response in vivo: From activation to memory formation
17. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
18. Crosstolerance: A pathway for inducing tolerance to peripheral tissue antigens
19. The use of HLA A2.1/p53 tetramers to visualize the impact of self tolerance on the TCR repertoire
20. Phenotypic and functional analysis of CD8+ T cells undergoing peripheral deletion in response to crosspresentation of self-antigen
21. Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes
22. T cell tolerance by clonal elimination in the thymus
23. Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes
24. + T cell response
25. Tolerance in T cell receptor transgenic mice involves deletion of non mature CD4+8- thymocytes
26. Peptide-induced deletion of CD8 T cells in vivo occurs via apoptosis in situ
27. + T cells
28. + T cell deletion induced by crosspresentation of self-antigens and favors autoimmunity
29. + T cells in vivo
30. T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides
31. + T cells
32. + T cells
33. T cell receptor Vb use predicts reactivity and tolerance to MlsA-encoded antigens
34. T cell deletion follows chronic antigen specific T cell activation in vivo
35. Tumor antigens are constitutively presented in the draining lymph nodes
36. Preferential localization of effector memory cells in nonlymphoid tissue
37. + T cells induced by low avidity engagement of T cell receptor
38. + T cell mediated spontaneous diabetes in neonatal mice
39. Ontogeny of T cell tolerance to peripherally expressed antigens
40. + T cell tolerance to peripherally expressed antigens
41. Characterization of CD8+ T lymphocytes that persist after peripheral tolerance to a self antigen expressed in the pancreas
42. Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice
43. Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: Role of anti-self (virus) immune response
44. + T cells are hyperreactive to antigenic challenge in vitro
45. MHC class I-restricted determinant on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity
46. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
47. T cell tolerance based on avidity thresholds rather than complete deletion allows maintenance of maximal repertoire diversity
48. + T cells without selection of higher affinity TCR
49. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice
50. + T cells to antigen stimulation in vivo
51. Ly-6C is a marker of memory CD8+ T cells
52. Kinetics of the response of naive and memory CD8 T cells to antigen: Similarities and differences