Nitrate and the GATA factor AreA are necessary for in vivo binding of NirA, the pathway-specific transcriptional activator of Aspergillus nidulans

Molecular Microbiology

Volumn 44, Issue 2, 2002, Pages 573-583

  Narendja, Frank ^a   Goller, Sabine P ^a   Wolschek, Markus ^a,b   Strauss, Joseph ^a  

^a UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

NITRATE; PROTEIN NIRA; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AREA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ALLELE; ARTICLE; ASPERGILLUS NIDULANS; BACTERIAL STRAIN; CHROMATIN STRUCTURE; CONTROLLED STUDY; GENE CONTROL; GENE INDUCTION; NITRATE METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN FUNCTION; REGULATORY MECHANISM; TRANSACTIVATION; TRANSCRIPTION INITIATION;

ASPERGILLUS NIDULANS; BASE SEQUENCE; BINDING SITES; CONSENSUS SEQUENCE; DNA-BINDING PROTEINS; FUNGAL PROTEINS; NITRATES; PROMOTER REGIONS (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; ZINC FINGERS;

ASPERGILLUS; BACTERIA (MICROORGANISMS); EMERICELLA NIDULANS;

EID: 0036231908     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2002.02911.x     Document Type: Article

References (53)

1. Suppressible alleles in a wide domain regulatory gene in Aspergillus nidulans
2. Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression
3. Comparative kinetics and reciprocal inhibition of nitrate and nitrite uptake in roots of non-induced and induced barley seedlings
4. Proline-independent binding of PUT3 transcriptional activator protein detected by footprinting in vivo
5. The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors
6. Nitrate uptake in Aspergillus nidulans and involvement of the third gene of the nitrate assimilation gene cluster
7. nirA, the pathway-specific regulatory gene of nitrate assimilation in Aspergillus nidulans, encodes a putative GAL4-type zinc finger protein and contains four introns in highly conserved regions
8. Molecular cloning and functional characterization of the pathway-specific regulatory gene nirA, which controls nitrate assimilation in Aspergillus nidulans
9. The Aspergillus nidulans transcription factor AlcR forms a stable complex with its half-site DNA: A NMR study
10. Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression
11. Nitrogen GATA factors participate in transcriptional regulation of vacuolar protease genes in Saccharomyces cerevisiae
12. Nitrate transport: A key step in nitrate assimilation
13. Folding of the gluco-corticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation
14. Interaction between major nitrogen regulatory protein NIT2 and pathway-specific regulatory factor NIT4 is required for their synergistic activation of gene expression in Neurospora crassa
15. Aspergillus nidulans contains a single actin gene which has unique intron locations and encodes a gamma-actin
16. Specific DNA binding of GAL4, a positive regulatory protein of yeast
17. 6 activator with a unique DNA recognition mode, requires inducer for in vivo binding
18. A rapid method for chromatin structure analysis in the filamentous fungus Aspergillus nidulans
19. Functional interaction of GATA1 with erythroid Kruppel-like factor and Sp1 at defined erythroid promoters
20. Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene
21. Structure of a HAP1-DNA complex reveals dramatically asymmetric DNA binding by a homodimeric protein
22. Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation
23. Detection of leucine-independent DNA site occupancy of the yeast Leu3p transcriptional activator in vivo
24. How does the GAL4 transcription factor recognize the appropriate DNA binding sitesin vivo?
25. The regulatory gene areA mediating nitrogen metabolite repression in Aspergillus nidulans. Mutations affecting specificity of gene activation alter a loop residue of a putative zinc finger
26. The relationship of regulatory proteins and DNase I hypersensitive sites in the yeast GAL1-10 genes
27. The GATA factor AreA is essential for chromatin remodelling in a eukaryotic bidirectional promoter
28. NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1
29. A small single-'finger' peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex
30. The zinc binuclear cluster activator AlcR is able to bind to single sites but requires multiple repeated sites for synergistic activation of the alcA gene in Aspergillus nidulans
31. Nitrogen metabolite signalling involves the C-terminus and the GATA domain of the Aspergillus transcription factor AREA and the 3′ untranslated region of its mRNA
32. Mutational analysis of the C-terminal region of AREA, the transcription factor mediating nitrogen metabolite repression in Aspergillus nidulans
33. The genetics of Aspergillus nidulans
34. Transformation of Aspergillus based on the hygromycin B resistance marker from Escherichia coli
35. Functional elements in the promoter region of the Aspergillus nidulans gpdA gene encoding glyceraldehyde-3-phosphate dehydrogenase
36. The intergenic region between the divergently transcribed niiA and niaD genes of Aspergillus nidulans contains multiple NirA binding sites which act bidirectionally
37. Subtle hydrophobic interactions between the seventh residue of the zinc finger loop and the first base of an HGATAR sequence determine promoter-specific recognition by the Aspergillus nidulans GATA factor AreA
38. The fungal GATA factors
39. Regulation of nitrate assimilation in Aspergillus nidulans
40. Comparative amino acid sequence analysis of the C6 zinc cluster family of transcriptional regulators
41. In vivo DNA-binding properties of a yeast transcription activator protein
42. The solution structure of a fungal AREA protein-DANN complex: An alternative binding mode for the basic carboxyl tail of GATA factors
43. The regulator of nitrate assimilation in ascomycetes is a dimer which binds a nonrepeated, asymmetrical sequence
44. The function of CreA, the carbon catabolite repressor of Aspergillus nidulans, is regulated at the transcriptional and post-transcriptional level
45. Structure-function aspects in the nitric oxide synthases
46. Transformation by integration in Aspergillus nidulans
47. Mutations to constitutivity and derepression are separate and separable in a regulatory gene of Aspergillus nidulans
48. crnA encodes a nitrate transporter in Aspergillus nidulans
49. Apparent genetic redundancy facilitates ecological plasticity for nitrate transport
50. Mutational analysis of AREA, a transcriptional activator mediating nitrogen metabolite repression in Aspergillus nidulans and a member of the 'streetwise' GATA family of transcription factors
51. In situ detection of protein-DNA interactions in filamentous fungi byin vivo footprinting
52. The negative-acting NMR regulatory protein of Neurospora crassa binds to and inhibits the DNA-binding activity of the positive-acting nitrogen regulatory protein NIT2