The zinc binuclear cluster activator AlcR is able to bind to single sites but requires multiple repeated sites for synergistic activation of the alcA gene in Aspergillus nidulans

Journal of Biological Chemistry

Volumn 272, Issue 36, 1997, Pages 22859-22865

  Panozzo, Cristina ^a   Capuano, Véronique ^a   Fillinger, Sabine ^b   Felenbok, Béatrice ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b AGROPARISTECH   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; ZINC;

ARTICLE; ASPERGILLUS NIDULANS; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; ENZYME ACTIVITY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REGULON; TRANSACTIVATION; TRANSCRIPTION REGULATION;

ASPERGILLUS NIDULANS; BINDING SITES; DNA, RECOMBINANT; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; PROMOTER REGIONS (GENETICS); TRANSCRIPTION FACTORS; ZINC;

ALCA; ASPERGILLUS; EMERICELLA NIDULANS;

EID: 0030983924     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.36.22859     Document Type: Article

References (40)

1. Fillinger, S., and Felenbok, B. (1996) Mol. Microbiol. 20, 475-488
2. Gwynne, D. I., Buxton, F. P., Sibley, S., Davies, R. W., Lockington, R. A., Scazzocchio, C., and Sealy-Lewis, H. M. (1987) Gene (Amst.) 51, 205-216
3. Pateman, J. H., Doy, C. H., Olson, J. E., Norris, U., Creaser, E. H., and Hynes, M. (1983) Proc. R. Soc. Lond. B Biol. Sci. 217, 243-264
4. Pickett, M., Gwynne, D. I., Buxton, F. P., Elliott, R., Davies, R. W., Lockington, R. A., Scazzocchio, C.. and Sealy-Lewis, H. M. (1987) Gene (Amst.) 51, 217-226
5. Creaser, E. H., Porter, R. L., Britt, K. A., Pateman, J. A., and Doy, C. H. (1984) Biochem. J. 225, 449-454
6. Lockington, R. A., Scazzocchio, C., Sequeval, D., Mathieu, M., and Felenbok, B. (1987) Mol. Microbiol. 1, 275-281
7. Felenbok, B., Sequeval, D., Mathieu, M., Sibley, S., Gwynne, D. I., and Davies, R. W. (1988) Gene (Amst.) 73, 385-396
8. Bailey, C., and Arst, H. N., Jr. (1975) Eur. J. Biochem. 51, 573-577
9. Dowzer, C. E. A., and Kelly, J. M. (1991) Mol. Cell. Biol. 11, 5701-5709
10. Mathieu, M., and Felenbok, B. (1994) EMBO J. 13, 4022-4027
11. Kulmburg, P., Sequeval, D., Lenouvel, F., Mathieu, M., and Felenbok, B. (1992) Mol. Cell. Biol. 12, 1932-1939
12. Kulmburg, P., Judewicz, N., Mathieu, M., Lenouvel, F., Sequeval, D., and Felenbok, B. (1992) J. Biol. Chem. 267, 21146-21153
13. Kulmburg, P., Mathieu, M., Dowzer, C. E. A., Kelly, J., and Felenbok, B. (1993) Mol. Microbiol. 7, 847-857
14. Fillinger, S., Panozzo, C., Mathieu, M., and Felenbok, B. (1995) FEBS Lett. 368, 547-550
15. Kulmburg, P., Prangé, T., Mathieu, M., Sequeval, D., Scazzocchio, C., and Felenbok, B. (1991) FEBS Lett. 280, 11-16
16. Sequeval, D., and Felenbok, B. (1994) Mol. Gen. Genet. 242, 33-39
17. Lenouvel, F., Nikolaev, I., and Felenbok, B. (1997) J. Biol. Chem. 272, 15521-15526
18. Felenbok. B. (1991) J. Biotechnol. 17, 11-18
19. Cove, D. J. (1966) Biochim. Biophys. Acta. 113, 51-56
20. Sealy-Lewis, H. M., and Fairhurst, V. (1992) Curr. Genet. 22, 293-296
21. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
22. Kunkel, T. A., Roberts, J. D., and Zabour, R. A. (1987) Methods Enzymol. 154, 367-382
23. Giniger, E., and Ptashne, M. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 382-386
24. Xu, H. E., Kodadek, T., and Johnston, S. A. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7677-7680
25. Felenbok, B., and Sealy-Lewis, H. (1994) in Genetics and Physiology of Aspergillus nidulans (Martinelli, S., and Kinghorn, J. R., eds) Vol. 29, pp. 141-179, Elsevier Scientific, Amsterdam
26. Scherling, P., and Holmberg, S. (1996) Nucleic Acids Res. 24, 4599-4607
27. Hu, J. C., O'Shea, E. K, Kim, P. S., and Sauer, R. T. (1990) Science 250, 1400-1403
28. Fillinger, S. (1996) Identification et étude fonctionnelle de nouveaux gènes appartenant au régulon éthanol chez Aspergillus nidulans, Ph.D. thesis, University of Paris-Sud, Orsay, France
29. Liang, S. D., Marmorstein, R., Harrisson, S. C., and Ptashne, M. (1996) Mol. Cell. Biol. 16, 3773-3780
30. Langdon, T., Sheerins, A., Ravagnani, A., Gielkens, M., Caddick, M. X., and Arst, H. N., Jr. (1995) Mol. Microbiol. 17, 877-888
31. Cheng, C., Kacherovsky, N., Dombek, K. M., Camier, S., Thukral, S. K., Rhim, E., and Young, E. T. (1994) Mol. Cell. Biol. 14, 3842-3852
32. Zhang, L., and Guarente, L. (1996) EMBO J 15, 4676-4681
33. Rastinejad, F., Perlmann, T., Evans, R. M., and Sigler, P. B. (1995) Nature 375, 203-211
34. Lin, Y.-S., Carey, M., Ptashne, M., and Green, M. R. (1990) Nature 345, 359-361
35. Carey, M., Lin, Y.-S., Green, M. R., and Ptashne, M. (1990) Nature 345, 361-364
36. Roeder, R. G. (1996) Trends Biochem. Sci. 21, 327-335
37. Verrijzer, C. P., and Tjian, R. (1996) Trends Biochem. Sci. 21, 338-342
38. Kaiser, K., and Meisterernst, M. (1996) Trends Biochem. Sci. 21, 342-345
39. Marmorstein, R., Carey, M., Ptashne, M., and Harrison, S. C. (1992) Nature 356, 408-414
40. Marmorstein, R., and Harrison, S. C. (1994) Genes Dev. 8, 2504-2512