Interaction between major nitrogen regulatory protein NIT2 and pathway- specific regulatory factor NIT4 is required for their synergistic activation of gene expression in Neurospora crassa

Molecular and Cellular Biology

Volumn 18, Issue 7, 1998, Pages 3983-3990

  Feng, Bo ^a   Marzluf, George A ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

REGULATOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; GENE ACTIVATION; GENE EXPRESSION REGULATION; MOLECULAR RECOGNITION; NEUROSPORA CRASSA; NITROGEN METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

NEUROSPORA; NEUROSPORA CRASSA;

EID: 0031807264     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.7.3983     Document Type: Article

References (36)

1. Arceci, R. J., A. A. J. King, M. C. Simon, S. H. Orkin, and D. B. Wilson. 1993. Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart. Mol. Cell. Biol. 13:2235-2246.
2. Ballario, P., P. Vittorioso, A. Magrelli, C. Talora, A. Cabibbo, and G. Macino. 1996. White collar-1, a central regulator of blue light responses in Neurospora, is a zinc finger protein. EMBO J. 15:1650-1657.
3. Cheng, X., M. J. Reginato, N. C. Andrews, and M. A. Lazar. 1997. The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2. Mol. Cell. Biol. 17:1407-1416.
4. Chiang, T. Y., and G. A. Marzluf. 1994. DNA recognition by the NIT2 nitrogen regulatory protein: importance of the number, spacing, and orientation of GATA core elements and their flanking sequences upon NIT2 binding. Biochemistry 33:576-582.
5. Chiang, T.-Y., and G. A. Marzluf. 1995. Binding affinity and functional significance of NIT2 and NIT4 binding sites in the promoter of the highly regulated nit-3 gene, which encodes nitrate reductase in Neurospora crassa. J. Bacteriol. 177:6093-6099.
6. Chiang, T. Y., R. Rai, T. G. Cooper, and G. A. Marzluf. 1994. DNA binding site specificity of the Neurospora global nitrogen regulatory protein NIT2: analysis with mutated binding sites. Mol. Gen. Genet. 245:512-516.
7. Crosthwaite, S. K., J. C. Dunlap, and J. J. Loros. 1997. Neurospora wc-1 and wc-2: transcription, photoresponses, and the origins of circadian rhythmicity. Science 276:763-769.
8. Davis, R. H., and F. J. deSerres. 1970. Genetic and microbiological research techniques for Neurospora crassa. Methods Enzymol. 17A:79-143.
9. Ebbole, D. 1990. Vectors for construction of translational fusions to β-galactosidase. Neurospora Newsl. 37:15-16.
10. Exley, G. E., J. D. Colandene, and R. H. Garrett. 1993. Molecular cloning, characterization, and nucleotide sequence of nit-6, the structural gene for nitrite reductase in Neurospora crassa. J. Bacteriol. 175:2379-2392.
11. 10a. Feng, B., H. Haas, and G. A. Marzluf. Unpublished observations.
12. Fu, Y. H., B. Feng, S. Evans, and G. A. Marzluf. 1995. Sequence-specific DNA binding by NIT4, the pathway-specific regulatory protein which mediates nitrate induction in Neurospora. Mol. Microbiol. 15:935-942.
13. Fu, Y. H., and G. A. Marzluf. 1987. Molecular cloning and analysis of the regulation of nit-3, the structural gene for nitrate reductase in Neurospora crassa. Proc. Natl. Acad. Sci. USA 84:8243-8247.
14. Garrett, R. H., and E. J. Cove. 1967. Formation of NADPH-nitrate reductase activity in vitro from Aspergillus nidulans niaD and cnx mutants. Mol. Gen. Genet. 149:179-186.
15. Kaushal, S., J. W. Schneider, B. Nadal-Ginard, and V. Mahdavi. 1994. Activation of the myogenic lineage by MEF2A, a factor that induces and cooperates with myoD. Science 266:1236-1240.
16. Kawana, M., M.-E. Lee, E. E. Quertermous, and T. Quertermous. 1995. Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene. Mol. Cell. Biol. 15:4225-4231.
17. Keleher, C. A., M. Redd, J. Schultz, M. Carlson, and A. D. Johnson. 1992. Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68:709-719.
18. Ko, L. J., and J. D. Engel. 1993. DNA-binding specificities of the GATA transcription factor family. Mol. Cell. Biol. 13:4011-4022.
19. Lee, Y.-H., S. C. Williams, M. Baer, E. Sterneck, F. J. Gonzalez, and P. F. Johnson. 1997. The ability of C/EBPβ but not C/EBPα to synergize with an SpI protein is specified by the leucine zipper and activation domain. Mol. Cell. Biol. 17:2038-2047.
20. Linden, H., and G. Macino. 1997. White collar 2, a partner in blue light signal transduction, controlling expression of light-regulated genes in Neurospora crassa. EMBO J. 16:98-107.
21. Marzluf, G. A. 1993. Regulation of sulfur and nitrogen metabolism in filamentous fungi. Annu. Rev. Microbiol. 47:31-55.
22. Marzluf, G. A. 1997. Genetic regulation of nitrogen metabolism in the fungi. Microbiol. Mol. Biol. Rev. 61:17-32.
23. Merika, M., and S. H. Orkin. 1993. DNA-binding specificity of GATA family transcription factors. Mol. Cell. Biol. 13:3999-4010.
24. Merika, M., and S. H. Orkin. 1995. Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins SP1 and EKLF. Mol. Cell. Biol. 15:2437-2447.
25. Molkentin, J. D., B. L. Black, J. F. Martin, and E. N. Olson. 1995. Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins. Cell 83:1125-1136.
26. Omichinski, J. G., G. M. Clore, O. Schaad, G. Felsenfeld, C. Trainor, E. Appella, S. J. Stahl, and A. M. Gronenborn. 1993. NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1. Science 261:438-446.
27. Orkin, S. H. 1992. GATA-binding transcription factors in hematopoietic cells. Blood 80:575-581.
28. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
29. Smith, D. B., and K. S. Johnson. 1988. Single-step purification of polypeptides expressed in E. coli as fusion with glutathione S-transferase. Gene 67: 31-40.
30. Tsang, A. P., J. E. Visvader, C. A. Turner, Y. Fujiwara, C. Yu, M. J. Weiss, M. Crossley, and S. H. Orkin. 1997. FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell 90:109-119.
31. Vollmer, S. J., and C. Yanofsky. 1986. Efficient cloning of genes of Neurosporn crassa. Proc. Natl. Acad. Sci. USA 83:4869-4873.
32. Xiao, X., Y. H. Fu, and G. A. Marzluf. 1995. The negative-acting NMR regulatory protein of Neurospora crassa binds to and inhibits the DNA-binding activity of the positive-acting nitrogen regulatory protein NIT2. Biochemistry 34:8861-8868.
33. Yamashiro, C. T., D. J. Ebbole, B.-U. Lee, R. E. Brown, C. Bourland, L. Madi, and C. Yanofsky. 1996. Characterization of rco-1 of Neurospora crassa, a pleiotropic gene affecting growth and development that encodes a homolog of Tup1 of Saccharomyces cerevisiae. Mol. Cell. Biol. 16:6218-6228.
34. Young, J. L., G. Jarai, Y. H. Fu, and G. A. Marzluf. 1990. Nucleotide sequence and analysis of nmr, a negative-acting regulatory gene in the nitrogen circuit of Neurospora crassa. Mol. Gen. Genet. 222:120-128.
35. Yuan, G.-F., Y.-H. Fu, and G. A. Marzluf. 1991. nit-4, a pathway-specific regulatory gene of Neurospora crassa, encodes a protein with a putative binuclear zinc DNA-binding domain. Mol. Cell. Biol. 11:5735-5745.
36. Zhou, L. W., H. Haas, and G. A. Marzluf. Submitted for publication.