Regulation of telomerase expression in human lymphocytes

Springer Seminars in Immunopathology

Volumn 24, Issue 1, 2002, Pages 23-33

  Weng, Nan Ping ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; RNA DIRECTED DNA POLYMERASE; TELOMERASE;

AGING; CELL DIFFERENTIATION; CELL DIVISION; CELL MATURATION; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION REGULATION; HUMAN; LEUKEMIA; LYMPHOCYTE; LYMPHOID TISSUE; LYMPHOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; SOMATIC CELL; TELOMERE;

AGING; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; LEUKEMIA; LYMPHOCYTES; MODELS, BIOLOGICAL; TELOMERASE;

EID: 0036196371     PISSN: 03444325     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00281-001-0093-4     Document Type: Review

References (56)

1. Telomere states and cell fates
2. Extension of life-span by introduction of telomerase into normal human cells
3. Telomerase activity in normal and malignant hematopoietic cells
4. Telomerase regulation during entry into the cell cycle in normal human T cells
5. Secondary structure of vertebrate telomerase RNA
6. Telomerase activity in B-cell non-Hodgkin lymphoma
7. The RNA component of human telomerase
8. Telomerase activation. One step on the road to cancer?
9. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
10. The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
11. Human telomerase contains evolutionarily conserved catalytic and structural subunits
12. Mortality and immortality at the cellular level. A review
13. Activation of telomerase in human lymphocytes and hematopoietic progenitor cells
14. Functional requirement of p23 and Hsp90 in telomerase complexes
15. Up-regulation of telomerase in human B lymphocytes occurs independently of cellular proliferation and with expression of the telomerase catalytic subunit
16. Telomerase is up-regulated in human germinal center B cells in vivo and can be re-expressed in memory B cells activated in vitro
17. Telomerase activity is induced by the stimulation to antigen receptor in human peripheral lymphocytes
18. Telomerase activity is induced in human peripheral B lymphocytes by the stimulation to antigen receptor
19. Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit
20. Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types
21. Specific association of human telomerase activity with immortal cells and cancer
22. Expression of TERT in early premalignant lesions and a subset of cells in normal tissues
23. Human lymphocyte telomerase is genetically regulated
24. Telomerase activity in preleukemia and acute myelogenous leukemia
25. Telomerase is controlled by protein kinase Cα in human breast cancer cells
26. Studies of the molecular mechanisms in the regulation of telomerase activity
27. Telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTER phosphorylation and nuclear translocation
28. Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytes
29. Germinal center development
30. + T cell clonal expansion is associated with telomerase up-regulation and telomere length preservation: A mechanism for rescue from replicative senescence
31. Expression of mouse telomerase catalytic subunit in embryos and adult tissues
32. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
33. Reversing time: Origin of telomerase
34. Telomerase catalytic subunit homologs from fission yeast and human
35. Telomerase activation in normal B lymphocytes and non-Hodgkin's lymphomas
36. Telomerase activity in Hodgkin's disease
37. Clinical implications of telomerase activity levels in acute leukemia
38. The flow cytometric analysis of telomere length in antigen-specific CD8(+) T cells during acute Epstein-Barr virus infection
39. Expression profile of the putative catalytic subunit of the telomerase gene
40. Involvement of 14-3-3 proteins in nuclear localization of telomerase
41. Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with Age
42. Decreased expression of telomerase-associated RNAs in the proliferation of stem cells in comparison with continuous expression in malignant tumors
43. Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage
44. Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts
45. Regulation of telomerase by alternate splicing of human tel-omerase reverse transcriptase (hTERT) in normal and neoplastic ovary, endometrium and myometrium
46. Regulation of telomerase RNA template expression in human T lymphocyte development and activation
47. Regulated expression of telomerase activity in human T lymphocyte development and activation
48. Telomere lengthening and telomerase activation during human B cell differentiation
49. Regulation of telomere length and telomerase in T and B cells: A mechanism for maintaining replicative potential
50. Tales of tails: Regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation, and aging
51. Telomerase activity in human germline and embryonic tissues and cells
52. Telomerase activity and telomere length in lymphocytes from patients with cutaneous T-cell lymphoma
53. Interferon alpha down-regulates telomerase reverse transcriptase and telomerase activity in human malignant and nonmalignant hematopoietic cells
54. Telomerase activity in plasma cell dyscrasias
55. Up-regulation of telomerase activity in human lymphocytes
56. Telomere shortening and apoptosis in telomerase-inhibited human tumor cells