Ex vivo generation of CD34+ cells from CD34- hematopoietic cells

Blood

Volumn 94, Issue 12, 1999, Pages 4053-4059

  Nakamura, Yoshihiko ^b   Ando, Kiyoshi ^a   Chargui, Jamel ^b   Kawada, Hiroshi ^b   Sato, Tadayuki ^b   Tsuji, Takashi ^b   Hotta, Tomomitsu ^b   Kato, Shunichi ^b  

^a TOKAI UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CYTOKINE; FLT3 LIGAND; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 6; METHYLCELLULOSE; STEM CELL FACTOR; THROMBOPOIETIN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; COLONY FORMING CELL; CONTROLLED STUDY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; XENOGRAFT; XENOTRANSPLANTATION;

EID: 0032785840     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.12.4053     Document Type: Article

References (21)

1. - progenitor cells. Blood 77:1218, 1991
2. Civin C, Alemeida-Porada G, Lee M, Olweus J, Terstappen L, Zanjani E: Sustained, retransplantable, multilineage engraftment of highly purified adult human bone marrow stem cells in vivo. Blood 88:4102, 1996
3. Krause DS, Fackler MJ, Civin CI, May WS: CD34: Structure, biology, and clinical utility. Blood 87:1, 1996
4. Yabe H, Yabe M, Hattori K, Hinohara T, Morimoto T, Nakamura Y, Noma M, Takei M, Kobayashi N, Tsuji K, Kato S: Successful engraftment of allogeneic CD34-enriched marrow cell transplantation from HLA-mismatched parental donors. Bone Marrow Transplant 17:985, 1996
5. Osawa M, Hanada K, Hamada H, Nakauchi H: Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273:242, 1996
6. Goodell M, Brose K, Paradis G, Conner A, Mulligan R: Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 183:1797, 1996
7. Goodell M, Rosenzweig M, Kim H, Marks D, DeMaria M, Paradis G, Grupp S, Seiff C, Mulligan R, Johnson R: Dye effex studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med 3:1337, 1997
8. + cells. Exp Hematol 26:353, 1998
9. Bhatia M, Bonnet D, Murdoch B, Gan O, Dick J: A newly discovered class of human hematopoietic cells with SCID-repopulating activity. Nat Med 4:1038, 1998
10. - progenitor cells in long-term cultures and semisolid assays. Blood 81:2916, 1993
11. - progenitors to maintain primitive function and immunophenotype in vitro. Exp Hematol 26:612, 1998
12. Xu M, Tsuji K, Ueda T, Mukouyama Y, Hara T, Yang F, Ebihara Y, Malsuoka S, Manabe A, Ito M, Miyajima A, Nakahata T: Stimulation of mouse and human primitive hematopoiesis by murine embryonic aorta-gonad-mesonephros-derived stromal cell lines. Blood 92:2032, 1998
13. Kawada H, Ando K, Tsuji T, Nakamura Y, Itagaki H, Shimakura Y, Inokuchi S, Kato S, Hotta T: Rapid ex vivo expansion of human umbilical cord hematopoietic progenitors using a novel culture system. Exp Hematol 27:904, 1999
14. Tsuji T, Ogasawara H, Aoki Y, Tsurumaki Y, Kodama H: Characterization of murine stromal cell clones established from bone marrow and spleen. Leukemia 10:803, 1996
15. - population of primitive human hematopoietic cells by using newly developed filter system. Blood 92:147b, 1998 (abstr, suppl 1)
16. Simmons DL, Satterthwaite AB, Tenen DG, Seed B: Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells. J Immunol 148:267, 1992
17. Inoko H, Ohta M: PCR-RFLP, in Hui KM, Bidwell JL (eds): Handbook of HLA Typing Techniques. Boca Raton, FL, CRC, 1993, p 9
18. Hogan CJ, Shpall EJ, McNulty O, Dick JE, Shultz LD, Keller G: Engraftment and development of human CD34(+)-enriched cells from umbilical cord blood in NOD/LtSz-scid/scid mice. Blood 90:85, 1997
19. Louache F, Debili N, Marandin A, Coulombel L, Vainchenker W: Expression of CD4 by human hematopoietic progenitors. Blood 84: 3344, 1994
20. Dexter TM, Allen TD, Lajtha LG: Conditions controlling the proliferation of hemopoietic stem cells in vitro. J Cell Physiol 91:335, 1977
21. Dorshkind K: Regulation of hemopoiesis by bone marrow stromal cells and their products. Annu Rev Immunol 8:111, 1990