Design, synthesis and biological evaluation of novel β-substituted indol-3-yl ethylamido melatoninergic analogues

Journal of Pharmacy and Pharmacology

Volumn 54, Issue 1, 2002, Pages 147-156

  Iakovou, K ^a   Varvaresou, A ^a   Kourounakis, A P ^b   Stead, K ^d   Sugden, D ^c   Tsotinis, A ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOBUTANECARBOXYLIC ACID[2 (1 CYCLOBUTANECARBONYL 1H INDOL 3 YL) 2 OXOETHYL]AMIDE; CYCLOBUTANECARBOXYLIC ACID[2 (1 METHYL 1H INDOL 3 YL) 2 OXOETHYL]AMIDE; CYCLOBUTANECARBOXYLIC ACID[2 (1H INDOL 3 YL) 2 OXOETHYL]AMIDE; CYCLOBUTANECARBOXYLIC ACID[2 HYDROXY 2 (1 METHYL 1H INDOL 3 YL)ETHYL]AMIDE; CYCLOPROPANECARBOXYLIC ACID[2 (1 CYCLOPROPANECARBONYL 1H INDOL 3 YL) 2 OXOETHYL]AMIDE; CYCLOPROPANECARBOXYLIC ACID[2 (1 METHYL 1H INDOL 3 YL) 2 OXOETHYL]AMIDE; CYCLOPROPANECARBOXYLIC ACID[2 (1H INDOL 3 YL) 2 OXOETHYL]AMIDE; CYCLOPROPANECARBOXYLIC ACID[2 HYDROXY 2 (1 METHYL 1H INDOL 3 YL)ETHYL]AMIDE; INDOLE DERIVATIVE; LIPID; MELATONIN; MELATONIN DERIVATIVE; MELATONIN RECEPTOR; N [2 (1 METHYL 1H INDOL 3 YL) 2 OXOETHYL]ACETAMIDE; N [2 (1 METHYL 1H INDOL 3 YL) 2 OXOETHYL]BENZAMIDE; N [2 (1 METHYL 1H INDOL 3 YL) 2 OXOETHYL]BUTYRAMIDE; N [2 (1 METHYL 1H INDOL 3 YL) 2 OXOETHYL]PROPIONAMIDE; N [2 (1H INDOL 3 YL) 2 OXOETHYL]ACETAMIDE; N [2 (1H INDOL 3 YL) 2 OXOETHYL]BUTYRAMIDE; N [2 (1H INDOL 3 YL) 2 OXOETHYL]PROPIONAMIDE; N [2 HYDROXY 2 (1 METHYL 1H INDOL 3 YL)ETHYL]ACETAMIDE; N [2 HYDROXY 2 (1 METHYL 1H INDOL 3 YL)ETHYL]BUTYRAMIDE; N [2 HYDROXY 2 (1 METHYL 1H INDOL 3 YL)ETHYL]PROPIONAMIDE; UNCLASSIFIED DRUG;

AGONIST; ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; LIPID PEROXIDATION; LIVER MICROSOME; MELANOPHORE; NONHUMAN; PHYSICAL CHEMISTRY; RAT; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; XENOPUS;

ANIMALS; ANTIOXIDANTS; FEMALE; INDOLES; LIPID PEROXIDATION; MELATONIN; MICROSOMES, LIVER; RATS; RATS, INBRED F344; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, MELATONIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036162418     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357021771869     Document Type: Article

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