The antidepressant drug fluoxetine is an inhibitor of human ether-a-go-go-related gene (HERG) potassium channels

Journal of Pharmacology and Experimental Therapeutics

Volumn 300, Issue 2, 2002, Pages 543-548

  Thomas, Dierk ^a   Gut, Bernd ^a   Wendt Nordahl, Gunnar ^a   Kiehn, Johann ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; FLUOXETINE; POTASSIUM CHANNEL; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT;

ARTICLE; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; GENE EXPRESSION; HEART PROARRHYTHMIA; HUMAN; IC 50; MEMBRANE POTENTIAL; PRIORITY JOURNAL; SYNCOPE; TACHYCARDIA; VOLTAGE CLAMP; XENOPUS;

ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BIOTRANSFORMATION; CATION TRANSPORT PROTEINS; CLONING, MOLECULAR; DNA-BINDING PROTEINS; ELECTROPHYSIOLOGY; ETHER-A-GO-GO POTASSIUM CHANNELS; FLUOXETINE; HUMANS; MEMBRANE POTENTIALS; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; TRANS-ACTIVATORS; XENOPUS LAEVIS;

EID: 0036151533     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.300.2.543     Document Type: Article

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