Collagenase-1 and collagenase-3 synthesis in normal and early experimental osteoarthritic canine cartilage: An immunohistochemical study

Journal of Rheumatology

Volumn 25, Issue 8, 1998, Pages 1585-1594

  Fernandes, Julio C ^a,b   Martel Pelletier, Johanne ^a,b,c   Lascau Coman, Viorica ^a   Moldovan, Florina ^a   Jovanovic, Dragan ^a   Raynauld, Jean Pierre ^a,b   Pelletier, Jean Pierre ^a,b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Department of Surgery ^*

^c CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Cartilage; Collagenase 1; Collagenase 3; Experimental model; Osteoarthritis

Indexed keywords

COLLAGEN; COLLAGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; COLLAGEN DEGRADATION; CONTROLLED STUDY; DOG; ENZYME LOCALIZATION; ENZYME SPECIFICITY; ENZYME SYNTHESIS; FEMUR CONDYLE; IMMUNOHISTOCHEMISTRY; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; TIBIA;

ANIMALS; CARTILAGE; COLLAGENASES; DOGS; IMMUNOHISTOCHEMISTRY; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 13; OSTEOARTHRITIS;

EID: 0031928795     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Mayne R. Cartilage collagens. What is their function, and are they involved in articular disease? Arthritis Rheum 1989;32:241-6.
2. Eyre DR, Wu JJ, Apone S. A growing family of collagens in articular cartilage: identification of 5 genetically distinct types. J Rheumatol 1987;14:25-7.
3. Watt SL, Lunstrum GP, McDonough AM, Keene DR, Burgeson RE, Morris NP. Characterization of collagen types XII and XIV from fetal bovine cartilage. J Biol Chem 1992;267:20093-9.
4. Pelletier JP, Martel-Pelletier J, Howell DS. Etiopathogenesis of osteoarthritis. In: Koopman WJ, editor. Arthritis and allied conditions. A textbook of rheumatology. 13th ed. Baltimore: Williams & Wilkins; 1997:1969-84.
5. Dean DD. Proteinase-mediated cartilage degradation in osteoarthritis. Semin Arthritis Rheum 1991;20:2-11.
6. 2-terminal portion of the smaller fragment released from both collagens. Biochemistry 1976;15:787-92.
7. Cole AA, Chubinskaya S, Schumacher BL, et al. Chondrocyte matrix metalloproteinase-8. Human articular chondroctyes express neutrophil collagenase. J Biol Chem 1996;271:11023-6.
8. Chubinskaya S, Huch K, Mikecz K, et al. Chondrocyte matrix metalloproteinase-8: up-regulation of neutrophil collagenase by interleukin-1β in human cartilage from knee and ankle joints. Lab Invest 1996;74:232-40.
9. Reboul P, Pelletier JP, Tardif G, Cloutier JM, Martel-Pelletier J. The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes: a role in osteoarthritis. J Clin Invest 1996;97:2011-9.
10. Ohuchi E, Imai K, Fujii Y, Sato H, Seiki M, Okada Y. Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. J Biol Chem 1997;272:2446-51.
11. Mitchell PG, Magna HA, Reeves LM, et al. Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J Clin Invest 1996;97:761-8.
12. Knaüper V, Lopez-Otin C, Smith B, Knight G, Murphy G. Biochemical characterization of human collagenase-3. J Biol Chem 1996;271:1544-50.
13. Brandt KD. Insights into the natural history of osteoarthritis provided by the cruciate-deficient dog. An animal model of osteoarthritis. Ann NY Acad Sci 1994;732:199-205.
14. Adams MA, Pelletier JP. Canine anterior cruciate ligament transection model of osteoarthritis. In: Greenwald RA Diamond HS, editors. CRC Handbook of animal models for the rheumatic diseases. Volume II. Boca Raton: CRC Press; 1990:57-81.
15. Pelletier JP, Faure MP, Di Battista JA, Wilhelm S, Visco D, Martel-Pelletier J. Coordinate synthesis of stromelysin, interleukin-1, and oncogene proteins in experimental osteoarthritis. An immunohistochemical study. Am J Pathol 1993;142:95-105.
16. Pelletier JP, Mineau F, Faure MP, Martel-Pelletier J. Imbalance between the mechanisms of activation and inhibition of metalloproteases in the early lesions of experimental osteoarthritis. Arthritis Rheum 1990;33:1466-76.
17. Pelletier JP, Martel-Pelletier J, Altman RD, Ghandur-Mnaymneh L, Howell DS, Woessner JF Jr. Collagenolytic activity and collagen matrix breakdown of the articular cartilage in the Pond-Nuki dog model of osteoarthritis. Arthritis Rheum 1983;26:866-74.
18. Martel-Pelletier J, Pelletier JP. Wanted - the collagenase responsible for the destruction of the collagen network in human cartilage. Br J Rheumatol 1996;35:818-20.
19. Pelletier JP, Mineau F, Raynauld JP, Woessner JF Jr, Gunja-Smith Z, Martel-Pelletier J. Intraarticular injections with methylprednisolone acetate reduce osteoarthritic lesions in parallel with chondrocyte stromelysin synthesis in experimental osteoarthritis. Arthritis Rheum 1994;37:414-23.
20. Mankin HJ, Dorfman H, Lippiello L, Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am 1971;53:523-37.
21. Moldovan F, Martel-Pelletier J, Hambor J, Cloutier JM, Pelletier JP. Collagenase-3 (MMP-13) is preferentially localized in situ in the deeper layer of human arthritic cartilage. In vitro mimicking effect by TGF-β. Arthritis Rheum 1997;40:1653-61.
22. Billinghurst RC, Dahlberg L, Ionescu M, et al. Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage. J Clin Invest 1997;99:1534-45.
23. Hollander AP, Pidoux I, Reiner A, Rorabeck B, Bourne R, Poole RA. Damage to type II in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration. J Clin Invest 1995;96:2859-69.
24. Nguyen Q, Mort JS, Roughley PJ. Preferential mRNA expression of prostromelysin relative to procollagenase and in situ localization in human articular cartilage. J Clin Invest 1992;89:1189-97.
25. Martel-Pelletier J, McCollum R, Fujimoto N, Obata K, Cloutier JM, Pelletier JP. Excess of metalloproteases over tissue inhibitor of metalloprotease may contribute to cartilage degradation in osteoarthritis and rheumatoid arthritis. Lab Invest 1994;70:807-15.
26. Pelletier JP, Di Battista JA, Roughley PJ, McCollum R, Martel-Pelletier J. Cytokines and inflammation in cartilage degradation. In: Moskowitz RW, editor. Osteoarthritis. Edition of Rheumatic Disease Clinics of North America. Philadelphia: W.B. Saunders; 1993:545-68.
27. Mort JS, Dodge GR, Roughley PJ, et al. Direct evidence for active metalloproteinases mediating matrix degradation in interleukin 1-stimulated human articular cartilage. Matrix 1993;13:95-102.
28. Pelletier JP, McCollum R, Cloutier JM, Martel-Pelletier J. Synthesis of metalloproteases and interleukin 6 (IL-6) in human osteoarthritic synovial membrane is an IL-1 mediated process. J Rheumatol 1995;22:109-14.
29. Zafarullah M, Pelletier JP, Cloutier JM, Martel-Pelletier J. Elevated metalloproteinase and tissue inhibitor of metalloproteinase mRNA in human osteoarthritic synovia. J Rheumatol 1993;20:693-7.
30. Pelletier JP, Martel-Pelletier J. Evidence for the involvement of interleukin 1 in human osteoarthritic cartilage degradation: protective effect of NSAID. J Rheumatol 1989;16:19-27.
31. Jovanovic D, Caron JP, Martel-Pelletier J, Fernandes JC, Ricketts T, Pelletier JP. The therapeutic effects of tenidap in canine experimental osteoarthritis: relationship with biochemical markers. J Rheumatol 1997;24:916-25.
32. Fernandes JC, Caron JP, Martel-Pelletier J, et al. Effects of tenidap on the progression of osteoarthritic lesions in a canine experimental model: suppression of metalloprotease and IL-1 activity. Arthritis Rheum 1997;40:284-94.
33. Harvey AK, Hrubey PS, Chandrasekhar S. Transforming growth factor-beta inhibition of interleukin-1 activity involves down-regulation of interleukin-1 receptors on chondrocytes. Exp Cell Res 1991;195:376-85.
34. Edwards DR, Murphy G, Reynolds JJ, et al. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J 1987;6:1899-904.
35. Johansson N, Westermarck J, Leppä S, et al. Collagenase 3 (matrix metalloproteinase 13) gene expression by HaCaT keratinocytes is enhanced by tumor necrosis factor-α and transforming growth factor-β. Cell Growth Differ 1997;8:243-50.
36. Morales TI, Roberts AB. Transforming growth factor beta regulates the metabolism of proteoglycans in bovine cartilage organ cultures. J Biol Chem 1988;263:12828-31.
37. Centrella M, Horowitz MC, Wozney JM, McCarthy TL. Transforming growth factor-β gene family members and bone. Endocr Rev 1994;15:27-39.
38. Noda M, Vogel R. Fibroblast growth factor enhances type b1 transforming growth factor gene expression in osteoblast-like cells. J Cell Biol 1989:109:2529-35.
39. Taketazu F, Kato M, Gobi A, et al. Enhanced expression of transforming growth factor-βs and transforming growth factor-β type II receptor in the synovial tissues of patients with rheumatoid arthritis. Lab Invest 1994;70:620-30.
40. Fava R, Olsen N, Keski-Oja J, Moses H, Pincus T. Active and latent forms of transforming growth factor β activity in synovial effusions. J Exp Med 1989;169:291-6.
41. Müssener A, Funa K, Kleinau S, Klareskog L. Dynamic expression of transforming growth factor-betas (TGF-beta) and their type I and type II receptors in the synovial tissue of arthritic rats. Clin Exp Immunol 1997;107:112-9.
42. Martel-Pelletier J, Hilal G, Pelletier JP, Ranger P, Lajeunesse D. Evidence for increased metabolic activity in human osteoarthritic subchondral bone expiants [abstract]. Arthritis Rheum 1997;40 Suppl:S182.