Pathophysiology of osteoarthritis

Osteoarthritis and Cartilage

Volumn 7, Issue 4, 1999, Pages 371-373

  Martel Pelletier, J ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; CYTOKINE; GELATINASE; TISSUE INHIBITOR OF METALLOPROTEINASE;

CARTILAGE; CONFERENCE PAPER; CYTOKINE PRODUCTION; ENZYME ACTIVATION; HUMAN; OSTEOARTHRITIS; OSTEOPHYTE; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0033166456     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1053/joca.1998.0214     Document Type: Conference Paper

References (16)

1. Pelletier JP, Martel-Pelletier J, Howell DS. Etiopathogenesis of osteoarthritis. In: Koopman WJ, Ed. Arthritis and Allied Conditions. A Textbook of Rheumatology. Baltimore: Williams & Wilkins 1997:1969-84.
2. Martel-Pelletier J, Faure MP, McCollum R, Mineau F, Cloutier JM, Pelletier JP. Plasmin, plasminogen activators and inhibitor in human osteoarthritic cartilage. J Rheumatol 1991;18:1863-71.
3. van de Loo FA, Joosten LA, van Lent PL, Arntz OJ, van den Berg WB. Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Effect of in situ blocking in murine antigen- and zymosan-induced arthritis. Arthritis Rheum 1995;38:164-72.
4. Plows D, Probert L, Georgopoulos S, Alexopoulou L, Kollias G. The role of tumour necrosis factor (TNF) in arthritis: Studies in transgenic mice. Rheumatol Eur 1995;Suppl 2:51-4.
5. Lotz M, Moats T, Villiger PM. Leukemia inhibitory factor is expressed in cartilage and synovium and can contribute to the pathogenesis of arthritis. J Clin Invest 1992;90:888-96.
6. Carroll GJ, Bell MC. Leukaemia inhibitory factor stimulates proteoglycan resorption in porcine articular cartilage. Rhaumatol Int 1993;13:5-8.
7. Jovanovic D, Di Battista JA, Martel-Pelletier J, Jolicoeur FC, He Y, Zhang M, et al. Interleukin-16 (IL-17) stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages. J Immunol 1998;160:3513-21.
8. Attur MG, Patel RN, Abramson SB, Amin AR. Interleukin-17 up-regulation of nitric oxide production in human osteoarthritis cartilage. Arthritis Rheum 1997;40:1050-3.
9. Pelletier JP, Mineau F, Ranger P, Tardif G, Martel-Pelletier J. The increased synthesis of inducible nitric oxide inhibits IL-1Ra synthesis by human articular chondrocytes: Possible role in osteoarthritic cartilage degradation. Osteoarthritis Cartilage 1996; 4:77-84.
10. Tetsuka T, Daphna-Iken D, Miller BW, Guan Z, Baier LD, Morrison AR. Nitric oxide amplifies interleukin 1-induced cyclooxygenase-2 expression in rat mesangial cells. J Clin Invest 1996;97:2051-6.
11. Amin AR, Attur MG, Patel RN, Thakker GD, Marshall PJ, Rediske J, et al. Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide. J Clin Invest 1997;99:1231-7.
12. Pelletier JP, Jovanovic D, Fernandes JC, Manning PT, Connor JR, Currie MG, et al. Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase. Arthritis Rheum 1998;41:1275-86.
13. Radin EL, Paul IL, Tolkoff MJ. Subchondral changes in patients with early degenerative joint disease. Arthritis Rheum 1970;13:400-5.
14. Radin EL, Rose RM. Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop 1986;213:34-40.
15. Westacott CI, Webb GR, Warnock MG, Sims JV, Elson CJ. Alteration of cartilage metabolism by cells from osteoarthritic bone. Arthritis Rheum 1997;40:1282-91.
16. Hilal G, Martel-Pelletier J, Pelletier JP, Ranger P, Lajeunesse D. Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: Possible role in subchondral bone sclerosis. Arthritis Rheum 1998;41:891-9.