Dietary modulation of age-related changes in cerebral pro-oxidant status

Neurochemistry International

Volumn 40, Issue 2, 2002, Pages 123-130

  Bondy, Stephen C ^a   Yang, Y Ellen ^a   Walsh, Thomas J ^a   Gie, Yuan Wen ^b   Lahiri, Debomoy K ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging brain; Coenzyme Q; Diet; Lipoic acid; Melatonin; Tocopherol; Ubiquinone

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; MELATONIN; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; THIOCTIC ACID; UBIQUINONE;

AGING; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENVIRONMENTAL EXPOSURE; MACROMOLECULE; MALE; METABOLISM; MOTOR ACTIVITY; MOUSE; NONHUMAN; ONSET AGE; OXIDATION; PRIORITY JOURNAL; RECALL; SENESCENCE;

AGING; ALPHA-TOCOPHEROL; ANALYSIS OF VARIANCE; ANIMALS; ANTIOXIDANTS; CEREBRAL CORTEX; DIET; GLUTATHIONE; MALE; MELATONIN; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MITOCHONDRIA; MOTOR ACTIVITY; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN SPECIES; SYNAPTOSOMES; THIOCTIC ACID; UBIQUINONE;

ANIMALIA;

EID: 0036139535     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(01)00084-5     Document Type: Article

References (44)

1. Neurohormone melatonin prevents cell damage: Effect on gene expression for antioxidant enzymes
2. Modification of physical movement in old C57BL/6 mice by DHEA and melatonin supplementation
3. Kyotorphin (l-tyrosyl-L-arginine) as a possible substrate for inducible nitric oxide synthase in rat glial cells
4. Flow cytometric studies of oxidative product formation by neutrophils: A graded dose response to membrane stimulation
5. Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MTPT) induced loss of striatal dopaminergic neurons in aged mice
6. Disruption of the potential across the synaptosomal plasma membrane and mitochondria by neurotoxic agents
7. Dietary alpha-tocopherol content modulates responses to moderate ethanol consumption
8. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of dye-binding
9. Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone
10. Particulates as contributory factors in neurodegenerative disease
11. Combined effect of lipoic acid and doxorubicin in murine leukemia
12. The effects of dietary restriction on mitochondrial dysfunction in aging
13. (R)-α-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage and increased metabolic rate
14. Long term dietary strawberry, spinach or vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficits
15. Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation
16. Effects of melatonin on neophobic responses in different strains of mice
17. Sensitive and rapid quantitation of oxygen reactive species in rat synaptosomes
18. Persistent protein damage despite reduced oxygen radical formation in the aging rat brain
19. Oxidative damage and cerebral aging
20. Evaluation of the probe 2′,7′-dichlorofluorescin diacetate as an indicator of reactive oxygen species formation and oxidative stress
21. Melatonin suppresses iron-induced neurodegeneration in rat brain
22. Effect of melatonin on lipid peroxidation induced by oxygen radicals
23. Effects of vitamin E on the blastogenic response of splenocytes and lipofuscin contents in the hearts and brains of aged mice
24. Melatonin affords protection against kainate-induced in vitro lipid peroxidation in brain
25. Oxidative damage caused by free radicals during catecholamine autoxidation: Protective effects of o-methylation and melatonin
26. Age-dependent change of NO synthase activity in the rat brain
27. An early stage mechanism of the age-associated mitochondrial dysfunction in the brain of SAMP8 mice, an age-associated neurodegeneration model
28. Effects of long-term administration of melatonin and a putative antagonist on the aging rat
29. Neuroprotection by the metabolic antioxidant alpha-lipoic acid
30. Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide
31. Pineal control of aging: Effect of melatonin and pineal grafting on aging mice
32. The role of the neurohormone melatonin against macromolecular oxidative damage
33. Mechanisms of brain injury with deep hypothermic circulatory arrest and protective effects of coenzyme Q10
34. Mitochondria, oxidative stress and aging
35. Effects of age and dietary antioxidants on cerebral electron transport chain activity
36. Heterogeneity of cellular glutathione among cells derived from a murine fibrosarcoma or a human renal cell carcinoma detected by flow cytometric analysis
37. Excess protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease
38. Role of mitochondria and oxidative stress in the aging process
39. Melatonin alters the metabolism of beta amyloid precursor protein in the neuroendocrine cell line PC 12
40. Phenoxyl radical-induced thiol-dependent generation of reactive oxygen species: Implications for benzene toxicity
41. Alpha-tocopherol in cerebrospinal fluid of subjects on high dose vitamin E in the DATATOP study
42. Reduction in the number of NADPH-diaphorase-positive cells in the cerebral cortex and striatum in aged rats
43. Antagonistic effect of melatonin against cyanide-induced seizures and acute lethality in mice
44. Restricted uptake of dietary coenzyme Q is in contrast to the unrestricted uptake of alpha-tocopherol into rat organs and cell