Cell compartmentalization in redox signaling

IUBMB Life

Volumn 52, Issue 1-2, 2001, Pages 7-16

  Pani, G ^a   Bedogni, B ^a   Colavitti, R ^a   Anzevino, R ^a   Borrello, S ^a   Galeotti, T ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Apoptosis; Mitochondria; MnSOD; Oncogenes; Rac 1; Reactive oxygen species; Signal transduction

Indexed keywords

RAS PROTEIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; CELL COMPARTMENTALIZATION; CELL DIVISION; CELL FUNCTION; CONFERENCE PAPER; CYTOSOL; MITOCHONDRION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; RESPIRATORY CHAIN; SENESCENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; APOPTOSIS; CELL AGING; CELL COMPARTMENTATION; CELL RESPIRATION; HUMANS; MITOCHONDRIA; NADPH OXIDASE; OXIDATION-REDUCTION; OXIDATIVE STRESS; RAS PROTEINS; SIGNAL TRANSDUCTION; SUPEROXIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036138276     PISSN: 15216543     EISSN: None     Source Type: Journal    
DOI: 10.1080/15216540252774702     Document Type: Conference Paper

References (66)

1. Free radicals as mediators of tissue injury and disease
2. Enzymic mechanisms of superoxide production
3. Reactive oxygen intermediates as apparently widely used messangers in the activation of the NFκB transcription factor and HIV
4. Oxygen radicals and signaling
5. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation
6. Reactive oxygen species and programmed cell death
7. NADPH oxidase and the respiratory burst
8. Regulation of tyrosine phosphorylation in neutrophils by the NADPH oxidase. Role of reactive oxygen intermediates
9. Inhibition of CD45 during neutrophil activation
10. 2 and vanadate in vitro
11. Identification of a superoxide generating NADPH oxidase system in human fibroblasts
12. Functional expression of NADPH oxidase components (alpha- and beta-subunits of cytochrome b558 and 45-kDa flavoprotein) by intrinsic human glomerular mesangial cells
13. Cell transformation by the superoxide-generating oxidase Mox1
14. Epidermal Growth Factor induced generation of hydrogen peroxide
15. 2 for plateled-derived growth factor signal transduction
16. Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes
17. Insulin-stimulated intracellular hydrogen peroxide production in rat epididymal fat cells
18. Endogenous oxygen radicals modulate protein tyrosine phosphorylation and JNK-1 activation in lectin-stimulated thymocytes
19. IL-2 gene expression and NF-κB activation through CD28 requires reactive oxygen production by 5-lipoxygenase
20. 2 in angiotensin II-induced vascular hypertrophy
21. Regulation of reactive oxygen species generation in fibroblasts by rac1
22. Rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-κB activation
23. 2 terminal-kinase
24. Rho family GTPases: The cytoskeleton and beyond
25. Ras effectors and their role in mitogenesis and oncogenesis
26. Rac mediates growth factor-induced arachidonic acid release
27. Tumor necrosis factor-alpha generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade
28. Suppression of Ras-induced apoptosis by the Rac GTPase
29. An essential role for Rac in Ras transformation
30. Mitochondrial free radical generation, oxidative stress and aging
31. Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF
32. Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate
33. Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis
34. A role for reactive oxygen species in endothelial cell anoikis
35. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
36. Superoxide in apoptosis
37. Tumor necrosis factor, other cytokines and disease
38. Dissection of TNF receptor 1 effector functions, JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
39. Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity
40. Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor
41. Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death
42. Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-κB and expression of ICAM-1
43. Role for mitochondrial oxidants as regulators of cellular metabolism
44. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1
45. Ras genes
46. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB
47. Requirement of NF-κB activation to suppress p53-independent apoptosis induced by oncogenic Ras
48. Apoptosis in cancer
49. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
50. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
51. Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells
52. New insights into tumor suppression PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
53. The tumor suppressor PTEN/MMAC1 dephosphorylates the lipid secon messanger phosphatidilinositol 3,4,5 triphosphate
54. Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
55. p19ARF links the tumour suppressor p53 to Ras
56. A model for p53-induced apoptosis
57. Deregulated manganese superoxide disrnutase expression and resistance to oxidative injury in p53-deficient cells
58. Opposing functions of Ki- and Ha-Ras genes in the regulation of redox signals
59. A redox signaling mechanism for density-dependent inhibition of cell growth
60. Suppression of intracellular Cu-Zn SOD results in enhanced motility and metastasis of Meth A sarcoma cells
61. Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts
62. Differential gene expression in p53-mediated apoptosis-resistant vs. apoptosis-sensitive tumor cell lines
63. Involvement of p85 in p53-dependent apoptotic response to oxidative stress
64. Redox regulation of activators
65. Cdc25 inhibition and cell cycle arrest by a synthetic thioalkyl vitamin K analogue